Laura Hilton

How are HIV services in the UK and Ireland managing care home residents living with HIV?

Benjamin Moshy, Tristan Barber, Maithili Varadarajan, Marta Boffito et autres

PURPOSE: The average age of people living with HIV in Europe is rising and with it the likelihood of entering long-term care. Little is known about the characteristics of people living with HIV in care homes and how their HIV care is …

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Long-term efficacy and safety of a treatment strategy for HIV infection using protease inhibitor monotherapy: 8-year routine clinical care follow-up from a randomised, controlled, open-label pragmatic trial (PIVOT)

Nicholas I. Paton, Alejandro Arenas‐Pinto, Wendy Hadley, David Stacey et autres

Background: Treatment-simplification strategies are important tools for patient-centred management. We evaluated long-term outcomes from a PI monotherapy switch strategy. Methods: Eligible participants attending 43 UK treatment centres had a viral load (VL) below 50 copies/ml for at least 24 weeks on combination …

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Optimized glucuronidation of dual pharmacology β-2 agonists/M3 antagonists for the treatment of COPD

Laura Hilton, Rachel Osborne, Amy S. Kenyon, Helen Baldock et autres

‘Inhalation by design’ concepts were developed to create novel dual pharmacology β-2 agonists-M3 antagonists, for the treatment of chronic obstructive pulmonary disorder. A key feature of this work is the combination of balanced potency and pharmacological duration with optimised glucuronidation through the …

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Inhalation by design: Dual pharmacology β-2 agonists/M3 antagonists for the treatment of COPD

Lyn H. Jones, Helen Baldock, Mark E. Bunnage, Jane L. Burrows et autres

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