Ziad Affas

Loeffler's Endomyocarditis With Embolic Stroke Secondary to Chronic Eosinophilic Leukemia With Therapy-Related Molecular Features

Sushmithaa Ramesh, Nadia Yousif, Ziad Affas, John Bajouka et autres

BACKGROUND: Loeffler's endomyocarditis is a severe manifestation of hypereosinophilia characterized by eosinophil-mediated myocardial injury, mural thrombus formation, and endomyocardial fibrosis. While often idiopathic, it may arise from clonal eosinophilic disorders carrying higher risk of end-organ damage. CASE SUMMARY: /L) with cytopenias prompted …

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Quadrivalvular Enterococcus faecalis Infective Endocarditis in a Patient With Complex Comorbidities

John Bajouka, C Matti, Ghaid Touza, Ziad Affas et autres

BACKGROUND: Panvalvular infective endocarditis (IE) involving all 4 cardiac valves is extremely rare, with a high mortality. Management is complex when surgical intervention is precluded by severe comorbidities. CASE SUMMARY: An 81-year-old woman with end-stage renal disease and metastatic bronchial carcinoma presented …

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Percutaneous Retrieval Strategies Following Left Atrial Appendage Occluder and Peri-Device Leak Closure Embolization

Wadie David, Ziad Affas, John Bajouka, Keyshla Pagán Morales et autres

BACKGROUND: Percutaneous LAAO is an established stroke-prevention strategy in atrial fibrillation patients unsuitable for long-term anticoagulation. Device embolization is uncommon but can cause severe complications requiring urgent intervention. ABSTRACT OF THE CASE: We report 2 related cases of device embolization associated with …

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26-CCC-18772-ACC TRAPPED IN THE TRABECULAE: LESSONS FROM LV NONCOMPACTION CARDIOMYOPATHY WITH RECURRENT STROKE AND SEVERE HEART FAILURE

Leonardo S. Romero-Barajas, Ziad Affas, Christian E. Machado

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Prophylactic Beta-Blocker Therapy in Patients Who Underwent Primary Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction With Preserved Left Ventricular Ejection Fraction: A Systematic Review and Meta-Analysis

Ziad Affas, Keyur Patel, Omr R Abuzahrieh, Saman Al Barznji et autres

The role of prophylactic beta-blocker therapy in patients treated with primary percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI) who have mildly reduced or preserved left ventricular ejection fraction (LVEF) remains a subject of debate. This systematic review and meta-analysis aimed …

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Health Care Resource Utilization for Patients With Suspected Myocardial Infarction

Joseph M. Miller, Bernard Cook, Satheesh Gunaga, Raef Fadel et autres

Importance: Evaluation for myocardial infarction (MI) in emergency departments (EDs) is a common, resource-intensive process. High-sensitivity cardiac troponin I (hs-cTnI) assays have become a key tool in rapidly ruling out MI, with the potential to reduce health care resource utilization. Objective: To …

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500.12 Cardiac Critical Care in a Community Setting: Cardiologist-Led vs. Intensivist-Led Outcomes

Mohammed Walji, Ziad Affas, Chris Jacob, Jelena Arnautovic

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Rapid Acute Coronary Syndrome Evaluation Over One Hour With High-Sensitivity Cardiac Troponin I: A United States-Based Stepped-Wedge, Randomized Trial

Joseph Miller, Bernard Cook, Chaun M. Gandolfo, Nicholas L. Mills et autres

STUDY OBJECTIVE: The real-world effectiveness and safety of a 0/1-hour accelerated protocol using high-sensitivity cardiac troponin (hs-cTn) to exclude myocardial infarction (MI) compared to routine care in the United States is uncertain. The objective was to compare a 0/1-hour accelerated protocol for …

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Abstract P155: Identifying Inpatient and Outpatient Factors That Reduce Heart Failure Exacerbation Readmissions

Sumeet Aujla, Kutiba Tabbaa, Ziad Affas, Samer Dubaisi et autres

Acute heart failure 30-day readmissions are associated with increased patient morbidity and mortality. Our aim is to identify systemic factors that can reduce heart failure readmissions, including the implementation of a heart failure care coordination team. We assessed the hypothesis that individualized …

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Mavacamten a Novel DiseaseSpecific Treatment for Hypertrophic Obstructive Cardiomyopathy: A Meta-Analysis and Systematic Review

Ziad Affas, Ghaid Touza, Rowaid Touza, Saif Affas et autres

The purpose of this study was to conduct a systematic evaluation and outcome assessment of published and on-going studies of mavacamten therapy to treat Hypertrophic cardiomyopathy (HCM). HCM is a common genetically based cardiac disease with an estimated prevalence of 1 in …

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Continuous positive airway pressure reduces the incidence of atrial fibrillation in patients with obstructive sleep apnea: A Meta-Analysis and Systematic Review

Ziad Affas, Saif Affas, Kutiba Tabbaa

INTRODUCTION: Obstructive sleep apnea (OSA) and atrial fibrillation (AF) are disorders that have increased in the United States during recent years. Earlier investigations have shown that underlying undiagnosed and unmanaged OSA plays a significant role in high rates and also as a …

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