Mohammed Ghunaim

Clinical Discovery and Molecular Analysis of Two Novel MSH2 Gene Mutations (p.Ala771Gly and p.Val797Gly) in Saudi Colorectal Cancer Patients: Potential Implications for Tumorigenesis

Mahmood Rasool, Absarul Haque, Mohammed Alharthi, Tainus Ali et autres

Background and Aims: Colorectal cancer (CRC) is a serious global health problem, ranking first in men and third in women among all cancers worldwide. The genetic basis for CRC remains unclear in most cases; therefore, the present study aimed to investigate the …

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Safety and equity in scaling minimally invasive surgery worldwide in 109 countries using cholecystectomy as a tracer procedure: a prospective cohort study

Sivesh K. Kamarajah, Omar Kouli, Wee Han Ng, Riinu Pius et autres

BACKGROUND: Minimally invasive surgery is rapidly expanding globally, yet there is insufficient knowledge of how to scale this technology safely and equitably across diverse health systems. We aimed to identify health-system factors associated with safe implementation of minimally invasive surgery globally, using …

Surgical outcomes of simultaneous vs. staged resection in colorectal cancer with liver metastases: a systematic review and meta-analysis

Mohammed Ghunaim, Ghaday M. Alrefaei, Raghad H. Alsharif, Alaa Mousli et autres

BACKGROUND AND OBJECTIVE: Colorectal cancer is among the most common global malignancies. Approximately 25% of patients present with liver metastases at diagnosis. Debate persists over whether to choose simultaneous or staged resection due to the varying evidence regarding outcomes and patient eligibility …

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ABO blood types can play a role in determining the aggressiveness of thyroid cancer in adult patients: a single-centre retrospective study

Mohammed Ghunaim, Zainab A Alkhalifah, Alwa Almontashri, Mohammed Aljehani et autres

BACKGROUND: Thyroid cancer is the most common endocrine malignancy. Previous research has linked the ABO blood group system to the risk and progression of different types of cancer. However, the association between specific blood groups and thyroid cancer risk and disease aggressiveness …

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Quality of life in different types of bariatric surgeries: A cross-sectional study

Mohammed Ghunaim, Rakan Abu Alqam, Hussain A Alkhalifah, Zainab A Alkhalifah et autres

Abstract Background: In recent decades, obesity emerged as a prominent health issue. Its treatments range from restrictive diet to invasive surgical procedures, the latter gaining popularity in patients with morbid obesity. However, outcomes between different procedures still range. This study was conducted …

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A systematic review and meta-analysis of randomized controlled trials for the management of ventral hernia: biologic versus synthetic mesh

Anas Alzahrani, Nawaf Alhindi, Sultan Alotaibi, Khalid F Alzibali et autres

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A prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts

Laura Bravo, Joana F F Simoes, Victor Roth Cardoso, Adewale Adisa et autres

BACKGROUND: Pulmonary complications are the most common cause of death after surgery. This study aimed to derive and externally validate a novel prognostic model that can be used before elective surgery to estimate the risk of postoperative pulmonary complications and to support …

Global access to technologies to support safe and effective inguinal hernia surgery: prospective, international cohort study

Maria Picciochi, Adesoji Ademuyiwa, Adewale Adisa, Anita Eseenam Agbeko et autres

Technological advancement is important to improve healthcare quality and safety, especially in surgery1. For patients with an inguinal hernia, mesh and minimally invasive surgery are the two main technologies that have improved healthcare quality and safety2,3. The use of mesh is proven …

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Access to and quality of elective care: a prospective cohort study using hernia surgery as a tracer condition in 83 countries

Aslıhan Dönmez, Aakansha Giri Goswami, Aashna Raheja, Aayush Bhadani et autres

BACKGROUND: Timely and safe elective health care facilitates return to normal activities for patients and prevents emergency admissions. Surgery is a cornerstone of elective care and relies on complex pathways. This study aimed to take a whole-system approach to evaluating access to …

A Newly Reported Late Complication of Endoscopic Fundoplication: A Case Report

Walid Bukhari, Hager Aref, Mohammed Ghunaim, Ahmed Elaryan

Endoscopic methods are emerging as a possible adjunct to surgery in the management of gastroesophageal reflux disease. Initially, endoscopic treatment has failed because of inefficient suturing devices, and although over many years it proved to be safe, it still can result in …

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Burnout among surgeons before and during the SARS-CoV-2 pandemic: an international survey

Mostafa Shalaby, Ahmed M. ElSheikh, Hosam Hamed, Ahmed Elsheik et autres

BACKGROUND: SARS-CoV-2 pandemic has had many significant impacts within the surgical realm, and surgeons have been obligated to reconsider almost every aspect of daily clinical practice. METHODS: This is a cross-sectional study reported in compliance with the CHERRIES guidelines and conducted through …

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Postoperative outcomes in distal pancreatectomy: A single-center experience

Mohammed H. Alharthi, Esraa Abdulrahman Alshehrani, Alaa M. Awlia, Moaz W. Abualfaraj et autres

Abstract Context: With the development of new advanced diagnostic modalities, distal pancreatectomy is nowadays performed more frequently. Pancreatic surgeries are considered overall highly morbid, with fistula development being the most serious and feared complication. Aim: This study aims to review a tertiary …

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