Shu‐Juan Xie

The lncRNA Brip1os Orchestrates IFN-γ–Mediated Inflammatory-Myogenic Crosstalk to Promote Muscle Regeneration

Yi Luo, Jia-Dong Zhang, Wei-Cai Chen, Wan-Xin Chen et autres

cn (code pays fourni par la source)

Correction: RNA‑binding protein CCDC137 activates AKT signaling and promotes hepatocellular carcinoma through a novel non‑canonical role of DGCR8 in mRNA localization

Shuang Tao, Shu‐Juan Xie, Diao Li-ting, Guo Lv et autres

Following publication of the original article [1], the authors identified an error in Fig. 1e due to an unintentional oversight during figure assembly.The same loading control images were mistakenly used for both sample 11 and sample 12.

cn (code pays fourni par la source)

RNA modification-mediated aberrant alternative splicing: An underlying driver of disease pathogenesis

Jin Zeng, Li‐Ting Diao, Shu‐Juan Xie, Zhen‐Dong Xiao

RNA modification and alternative splicing are central mechanisms in the regulation of eukaryotic gene expression. RNA modifications, which occur in a variety of chemical forms, exert widespread influences on RNA structure, stability and function. Meanwhile, alternative splicing significantly contributes to proteomic diversity …

cn (code pays fourni par la source)

Deep Learning Retrieval and Prediction of Summer Average Near-Surface Air Temperature in China with Vegetation Regionalization

Wen‐Ting Lu, Zhefan Li, Ya Wen, Shu‐Juan Xie et autres

Retrieving and predicting summer average near-surface air temperature (SANSAT) across China remain challenging due to the country’s complex topography and heterogeneous vegetation cover. This study proposes an innovative deep learning framework that incorporates vegetation regionalization to achieve high-precision spatiotemporal temperature retrieval and …

cn, Rwanda (code pays fourni par la source)

Stage-specific requirement for METTL3-dependent m6A epitranscriptomic regulation during myogenesis

Ye-Ya Tan, Yangwen Ou, Qiao Zuo, Yi Luo et autres

Abstract The regulatory role of N6-methyladenosine (m6A) modification in skeletal muscle myogenesis and muscle homeostasis remains poorly characterized, particularly regarding the functional significance of methyltransferase-like 3 (METTL3), the catalytic subunit of the m6A methyltransferase complex (MTC), in myogenic regulation. Through systematic investigation …

cn (code pays fourni par la source)

Simplifying the protocol for low-pollution-risk, efficient mouse myoblast isolation and differentiation

Yi Luo, Jia-Dong Zhang, Weicai Chen, Wanxin Chen et autres

Summary Myoblasts are the primary effector cells that play crucial roles in myogenesis and muscle regeneration following injury. However, isolating purified primary myoblasts from murine skeletal muscle poses challenges for junior researchers. Here, we present a simplified, low-risk, and optimized protocol for …

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CRISPR/Cas13 sgRNA‐Mediated RNA–RNA Interaction Mapping in Live Cells with APOBEC RNA Editing

Li‐Ting Diao, Shu‐Juan Xie, Wan‐Yi Xu, Hai‐Hui Zhang et autres

Current research on long non-coding RNA (lncRNA) has predominantly focused on identifying their protein partners and genomic binding sites, leaving their RNA partners largely unknown. To address this gap, the study has developed a method called sarID (sgRNA scaffold assisted RNA-RNA interaction …

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A Polarization-Reconfigurable Magnetoelectric Dipole Antenna for 5G Millimeter-Wave Application

Shu‐Juan Xie, Weidong Chen, Xiang Zhang, Chang Chen

This paper presents a polarization-reconfigurable magneto electric (ME) dipole antenna with a wide axial ratio (AR) bandwidth and good gain for 5G millimeter-wave (MMW) applications. The radiation structure of the antenna is a ME dipole composed of four vertical metallic pins and …

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LncRNA 4930581F22Rik promotes myogenic differentiation by regulating the ERK/MAPK signaling pathway

Wei-Cai Chen, Wanxin Chen, Ye-Ya Tan, Ying-Jun Xu et autres

The skeletal muscle is the largest organ in mammals and is the primary motor function organ of the body. Our previous research has shown that long non-coding RNAs (lncRNAs) are significant in the epigenetic control of skeletal muscle development. Here, we observed …

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The NLRP3 molecule influences the therapeutic effects of mesenchymal stem cells through Glut1-mediated energy metabolic reprogramming

Jingrou Chen, Shu‐Juan Xie, Dongbo Qiu, Maosheng Xie et autres

INTRODUCTION: Numerous studies demonstrated that NLRP3 has been implicated in the pathogenesis of inflammatory bowel disease (IBD). Mesenchymal stem cells (MSCs) regulated the NLRP3 inflammasome, which has emerged as a novel therapeutic approach for treating IBD. OBJECTIVES: The exact role of NLRP3 …

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Pseudouridine synthase 1 promotes hepatocellular carcinoma through mRNA pseudouridylation to enhance the translation of oncogenic mRNAs

Yanxia Hu, Li‐Ting Diao, Ya‐Rui Hou, Guo Lv et autres

BACKGROUND AND AIMS: Pseudouridine is a prevalent RNA modification and is highly present in the serum and urine of patients with HCC. However, the role of pseudouridylation and its modifiers in HCC remains unknown. We investigated the function and underlying mechanism of …

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RNA-binding protein CCDC137 activates AKT signaling and promotes hepatocellular carcinoma through a novel non-canonical role of DGCR8 in mRNA localization

Shuang Tao, Shu‐Juan Xie, Li‐Ting Diao, Guo Lv et autres

BACKGROUND: RNA binding proteins (RBPs)-regulated gene expression play a vital role in various pathological processes, including the progression of cancer. However, the role of RBP in hepatocellular carcinoma (HCC) remains much unknown. In this study, we aimed to explore the contribution of …

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