Fengsheng Chen

Research on Short Term Power Load Forecasting Method Based on Large Language Model

Jing Ke, Zhongan Yu, Zihao Deng, Fengsheng Chen

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β-sitosterol suppresses malignant biological behaviors and glycolysis via modulating YBX1-hnRNP K interaction in non-small cell lung cancer

Guolu Ma, Jianyu Feng, Jianying Zeng, Rongxin Liao et autres

Non-small cell lung cancer (NSCLC) is the most prevalent form of lung malignancy. As a type of phytosterol, β-sitosterol shares structural similarities with cholesterol and has been shown to possess multiple pharmacological properties. This study aimed to investigate how β-sitosterol influences the …

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ARHGAP21 enhances metastasis in hepatocellular carcinoma by inhibiting ubiquitination of filamin A

Huijun Yao, Ziping Xie, Xingyu Tao, Xingyi Zhong et autres

Rho GTPase-activating protein 21 (ARHGAP21) plays a role in the occurrence and development of certain cancers, but its function in hepatocellular carcinoma (HCC) remains unclear. In this study, elevated ARHGAP21 expression was observed in both HCC cell lines and tissues and correlated …

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Corrigendum to “Erianin serves as an NFATc1 inhibitor to prevent breast cancer-induced osteoclastogenesis and bone destruction” Adv. Res. 69 (2025) 399-411]

Jiehuang Zheng, Weili He, Yan Chen, Lihong Li et autres

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Intelligent Planning Method for "Head Link" of Feeder Considering Pipeline-Grid Coupling : Intelligent Planning of Distribution Network

Chenkang Tang, Zhongan Yu, Fengsheng Chen

In view of the lack of planning methods for the transformation of the "head link" problem of feeders in the existing research, the solution of this problem still needs to be realized manually. To this end, this paper proposes an intelligent transformation …

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Ammonium tetrathiomolybdate attenuates acetaminophen-induced acute liver failure by inhibiting the TRPV4/Calcium/NF-κB signaling pathway

Lingzhi Long, Huijun Yao, Zhiqin Zhu, Ziping Xie et autres

Acute liver failure (ALF), characterized by fulminant hepatic necrosis and excessive inflammatory-oxidative cascades, remains a critical clinical challenge with limited therapeutic options. This study investigates the therapeutic potential of ammonium tetrathiomolybdate (ATTM)-a copper-chelating agent with multimodal anti-inflammatory and antioxidant properties-in acetaminophen (APAP)-induced …

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THSWD upregulates the LTF/AMPK/mTOR/Becn1 axis and promotes lysosomal autophagy in hepatocellular carcinoma cells by regulating gut flora and metabolic reprogramming

Zhiqin Zhu, Shi Zuo, Zhiqi Zhu, Chen Wang et autres

THSWD has the effect of reducing inflammation, improving microcirculation, and regulating immune status in patients with hepatocellular carcinoma. Regardless of its clear therapeutic effect, the underlying mechanism of action against hepatocellular carcinoma is not clear. To identify critical gut microbiota and its …

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EFNA4-enhanced deubiquitination of SLC7A11 inhibits ferroptosis in hepatocellular carcinoma

Zhiqin Zhu, Yangfeng Du, Lingzhi Long, Ziping Xie et autres

EFNA4, a member of the Ephrin-A ligand family, may influence hepatocellular carcinoma cells through two distinct mechanisms: one reliant on specific Eph receptor binding and the other independent of receptor involvement. However, EFNA4's influence on HCC via non-Eph receptor pathways remains unclear. …

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Kaempferol Remodels Liver Monocyte Populations and Treats Hepatic Fibrosis in Mice by Modulating Intestinal Flora and Metabolic Reprogramming

Zhiqin Zhu, Zhiqi Zhu, Zhenyi Shi, Chen Wang et autres

Changes in gut flora are associated with liver fibrosis. The interactions of host with intestinal flora are still unknown, with little research investigating such interactions with comprehensive multi-omics data. The present work analyzed and integrated large-scale multi-omics transcriptomics, microbiome, metabolome, and single-cell …

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PMSM control based on nonsingular fast terminal sliding mode

Jiawei Liu, Zhongan Yu, Fengsheng Chen

Addressing the challenges of load torque fluctuations and the limitations of conventional control systems, such as excessive overshoot and sluggish response times, in the speed regulation of permanent magnet synchronous motors (PMSMs), this study introduces an enhanced variable speed attainment rate and …

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EFNA5 suppresses cell proliferation and tumor metastasis in hepatoma via epithelial-to-mesenchymal transition

Zhiqin Zhu, Shulu Hu, Yangfeng Zhang, Xiuqiong Wu et autres

BACKGROUND: EphrinA5 belongs to a subclass of ephrin ligands. Abnormal signal transduction of EFNA5 shows a relationship to the development of various tumors. In this study, we explored the level of EFNA5 in hepatoma cells and the influence of up regulation of …

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Intelligent Planning Method for “Big Branch” of Feeder Considering Pipeline-Grid Coupling Intelligent Planning of Distribution Network

Zhongan Yu, Fengsheng Chen

Due to the lack of effective intelligent planning methods, distribution networks planning has to heavily rely on manual planning, resulting in low efficiency. Here, we propose an intelligent planning method for “big branch” problem. Firstly, a coupling model between the pipeline and …

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