Charlotta Karner

HTA119 Mapping a Path to Standardized Evidence Quality Tools Across EU HTA Agencies and NICE: Is EU Joint Clinical Assessment Guidance Falling Behind?

Boris Mayer, Charlotta Karner, Grammati Sarri, Andreas P Freitag

Abrocitinib, tralokinumab and upadacitinib for treating moderate-to-severe atopic dermatitis

Steven J Edwards, Charlotta Karner, Tracey Jhita, Samantha Barton et autres

Background: Atopic dermatitis is a chronic relapsing inflammatory skin condition. One of the most common skin disorders in children, atopic dermatitis typically manifests before the age of 5 years, but it can develop at any age. Atopic dermatitis is characterised by dry, …

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Prognostic tools for identification of high risk in people with Crohn’s disease: systematic review and cost-effectiveness study

Steven J Edwards, Samantha Barton, Mariana Bacelar, Charlotta Karner et autres

BACKGROUND: Crohn's disease is a lifelong condition that can affect any segment of the gastrointestinal tract. Some people with Crohn's disease may be at higher risk of following a severe course of disease than others and being able to identify the level …

Clinical estimates informing the model

Steven J Edwards, Samantha Barton, Mariana Bacelar, Charlotta Karner et autres

Time to surgery curves

Steven J Edwards, Samantha Barton, Mariana Bacelar, Charlotta Karner et autres

Cost-effectiveness results

Steven J Edwards, Samantha Barton, Mariana Bacelar, Charlotta Karner et autres

Drug price discount scenarios

Steven J Edwards, Samantha Barton, Mariana Bacelar, Charlotta Karner et autres

Risk of developing a complication or need for surgery based on number of positive biomarkers in the IBDX tool

Steven J Edwards, Samantha Barton, Mariana Bacelar, Charlotta Karner et autres

Time to relapse truncated curves

Steven J Edwards, Samantha Barton, Mariana Bacelar, Charlotta Karner et autres

Cost-effectiveness acceptability curve

Steven J Edwards, Samantha Barton, Mariana Bacelar, Charlotta Karner et autres

Results of the review of prognostic test accuracy and clinical impact

Steven J Edwards, Samantha Barton, Mariana Bacelar, Charlotta Karner et autres

Search strategies and list of excluded studies for literature review to inform estimates of clinical effectiveness of induction (step up and top down) and maintenance treatment

Steven J Edwards, Samantha Barton, Mariana Bacelar, Charlotta Karner et autres