Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Bożena Gabryel, Hkw Law, Angelo De Milito, Jason E. Gestwicki et autres
12
3 citations
UNC Libraries
Skye C McIver
Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.
21Publications signalées
6767Citations signalées
0Affiliations récentes
Les domaines associés
Sperm and Testicular FunctionMicroRNA in disease regulationTesticular diseases and treatmentsEpigenetics and DNA MethylationRNA modifications and cancer
Les publications récentes
Integrating Enhancer Mechanisms to Establish a Hierarchical Blood Development Program
Charu Mehta, Kirby D. Johnson, Xin Gao, Irene M. Ong et autres
Abstract GATA-2 levels must be stringently regulated to ensure normal hematopoiesis, and human GATA-2 mutations cause hematologic disorders. GATA-2-regulated enhancers differentially control Gata2 expression in hematopoietic stem/progenitor cells and are essential for hematopoiesis and embryonic development. Mechanisms underlying how the enhancers control …
us (code pays fourni par la source)
4 citations
Blood
Dissecting Regulatory Mechanisms Using Mouse Fetal Liver-Derived Erythroid Cells
Skye C McIver, Kyle J. Hewitt, Xin D. Gao, Charu Mehta et autres
us (code pays fourni par la source)
18 citations
Methods in molecular biology
Integrating Enhancer Mechanisms to Establish a Hierarchical Blood Development Program
Charu Mehta, Kirby D. Johnson, Xin Gao, Irene M. Ong et autres
Hematopoietic development requires the transcription factor GATA-2, and GATA-2 mutations cause diverse pathologies, including leukemia. GATA-2-regulated enhancers increase Gata2 expression in hematopoietic stem/progenitor cells and control hematopoiesis. The +9.5-kb enhancer activates transcription in endothelium and hematopoietic stem cells (HSCs), and its deletion …
us (code pays fourni par la source)
50 citations
Cell Reports
Enhancer mechanisms governing developmental and regenerative hematopoietic programs
Emery H. Bresnick, Kyle J. Hewitt, Charu Mehta, Kirby D. Johnson et autres
us, kr (code pays fourni par la source)
0 citations
Experimental Hematology
Orchestrating Developmental Signaling to Balance Erythroblast Proliferation and Differentiation
Skye C McIver, Koichi R Kasumura, Elsa Davids, Yoon-A Kang et autres
Abstract The highly conserved exosome complex mediates the degradation and processing of multiple classes of RNAs. How this post-transcriptional RNA- and gene-regulatory machine impacts cell fate decisions and differentiation is poorly understood. Previously, we demonstrated that exosome complex subunits confer an erythroid …
us (code pays fourni par la source)
0 citations
Blood
Exosome complex orchestrates developmental signaling to balance proliferation and differentiation during erythropoiesis
Skye C McIver, Koichi Ricardo Katsumura, Elsa Davids, Peng Liu et autres
Since the highly conserved exosome complex mediates the degradation and processing of multiple classes of RNAs, it almost certainly controls diverse biological processes. How this post-transcriptional RNA-regulatory machine impacts cell fate decisions and differentiation is poorly understood. Previously, we demonstrated that exosome …
us (code pays fourni par la source)
40 citations
eLife
Author response: Exosome complex orchestrates developmental signaling to balance proliferation and differentiation during erythropoiesis
Skye C McIver, Koichi Ricardo Katsumura, Elsa Davids, Peng Liu et autres
Red blood cells supply an animal’s tissues with the oxygen they need to survive. These cells circulate for a certain amount of time before they die. To replenish the red blood cells that are lost, first a protein called stem cell factor …
us (code pays fourni par la source)
0 citations
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Daniel J. Klionsky, Kotb Abdelmohsen, Akihisa Abe, Md. Joynal Abedin et autres
0
us, jp, il, gb, ca, it, be, es, fr, at, qa, ie, de, mx, ar, dk, au, ch, kr, pl (code pays fourni par la source)
6023 citations
Autophagy
Navigating Transcriptional Coregulator Ensembles to Establish Genetic Networks
Andrew DeVilbiss, Nobuyuki Tanimura, Skye C McIver, Koichi Ricardo Katsumura et autres
us (code pays fourni par la source)
19 citations
Current topics in developmental biology/Current Topics in Developmental Biology
The RNA-Degrading Exosome Complex Is an Endogenous Suppressor of Erythroid Maturation
Skye C McIver, Yoon-A Kang, Andrew DeVilbiss, Chelsea A. O’Driscoll et autres
Abstract Complex genetic networks control hematopoietic stem cell differentiation into progenitors that give rise to billions of erythrocytes daily. We demonstrated that the master regulator of erythropoiesis, GATA-1, induces expression of genes encoding components of the autophagy machinery. In this context, the …
us (code pays fourni par la source)
0 citations
Blood
The exosome complex establishes a barricade to erythroid maturation
Skye C McIver, Yoon-A Kang, Andrew DeVilbiss, Chelsea A. O’Driscoll et autres
Complex genetic networks control hematopoietic stem cell differentiation into progenitors that give rise to billions of erythrocytes daily. Previously, we described a role for the master regulator of erythropoiesis, GATA-1, in inducing genes encoding components of the autophagy machinery. In this context, …
us (code pays fourni par la source)
66 citations
Blood
BNTIC News n’est pas le producteur de ces données. Les publications sont interrogées à la demande dans Crossref, OpenAIRE, DOAJ, Europe PMC, HAL, DataCite, AfricArXiv, ROR et la Banque mondiale, sans clé d’accès. OpenAlex reste optionnel. Aucun service payant n’est nécessaire et aucune donnée externe n’est enregistrée en base. Consulter les sources et leurs limites.