Chunbo Qin

The Secular Trend On Fitness Parameter In Chinese Male College Students From 2013 To 2021

Chunbo Qin, Xi Jin, Zhonghui John Wang, Wen Yang

Trends of Physical Fitness (PF) can predict group physical activity and develop measurement interventions to promote health. PURPOSE: The purpose of this cross-sectional study was to explore the trends of fitness parameters in male college students from 2013 to 2021 in southern …

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DECREASE IN PHYSICAL FITNESS IN SOUTH CHINA COLLEGE STUDENTS FROM 2015 TO 2018

Chunbo Qin, Xi Jin, Daixi Xie, Wen Yang et autres

Physical fitness (PF) is important for human health and movement throughout the lifespan. PURPOSE: The aim of this study was to explore changes in physical fitness in college students from the first year of college to the third year of college. METHODS: …

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Aggregated LDL in Contact With Macrophages Induces Local Increases in Free Cholesterol Levels That Regulate Local Actin Polymerization

Inna Grosheva, Abigail S. Haka, Chunbo Qin, Lynda M. Pierini et autres

OBJECTIVE: Interaction of macrophages with aggregated matrix-anchored lipoprotein deposits is an important initial step in atherogenesis. Aggregated lipoproteins require different cellular uptake processes than those used for endocytosis of monomeric lipoproteins. In this study, we tested the hypothesis that engagement of aggregated …

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Elevated Cholesterol Levels in the Plasma Membranes of Macrophages Inhibit Migration by Disrupting RhoA Regulation

Tomokazu Nagao, Chunbo Qin, Inna Grosheva, Frederick R. Maxfield et autres

OBJECTIVE: Atherogenesis begins as small subendothelial accumulations of foam cells that develop through unregulated uptake of modified and aggregated low-density lipoprotein (LDL). The reason why foam cells remain in the atherosclerotic plaque rather than migrating out of the area is unclear. We …

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Expression and characterization of Arabidopsis phospholipase Dγ2

Chunbo Qin, Maoyin Li, Wensheng Qin, Sung Chul Bahn et autres

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ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophages

Andreas Werner Jehle, Shyra J. Gardai, Suzhao Li, Patrick Linsel‐Nitschke et autres

ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophages

Andreas Werner Jehle, Shyra J. Gardai, Suzhao Li, Patrick Linsel‐Nitschke et autres

The mammalian ATP-binding cassette transporters A1 and A7 (ABCA1 and -A7) show sequence similarity to CED-7, a Caenorhabditis elegans gene that mediates the clearance of apoptotic cells. Using RNA interference or gene targeting, we show that knock down of macrophage ABCA7 but …

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Double Knockouts of Phospholipases Dζ1 and Dζ2 in Arabidopsis Affect Root Elongation during Phosphate-Limited Growth But Do Not Affect Root Hair Patterning

Maoyin Li, Chunbo Qin, Ruth Welti, Xuemin Wang

Root elongation and root hair formation are important in nutrient absorption. We found that two Arabidopsis (Arabidopsis thaliana) phospholipase Ds (PLDs), PLDzeta1 and PLDzeta2, were involved in root elongation during phosphate limitation. PLDzeta1 and PLDzeta2 are structurally different from the majority of …

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Elevated Plasma Membrane Cholesterol Content Alters Macrophage Signaling and Function

Chunbo Qin, Tomokazu Nagao, Inna Grosheva, Frederick R. Maxfield et autres

OBJECTIVE: During atherogenesis, macrophages migrate into the subendothelial space where they ingest deposited lipoproteins, accumulate lipids, and transform into foam cells. It is unclear why these macrophages do not remove their lipid loads from the region. This study was aimed at testing …

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Phospholipase Dα1-derived phosphatidic acid interacts with ABI1 phosphatase 2C and regulates abscisic acid signaling

Wenhua Zhang, Chunbo Qin, Jian Hua Zhao, Xuemin Wang

Phospholipase D (PLD) and protein phosphatase 2C (PP2C) both play a role in mediating plant responses to abscisic acid (ABA). In this article, we show that PLD alpha 1 and its product, phosphatidic acid (PA), regulate a PP2C, ABI1, which is a …

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Evolutionary conservation of physical and functional interactions between phospholipase D and actin

David J. Kusner, James A. Barton, Chunbo Qin, Xuemin Wang et autres

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Two Novel Types of Arabidopsis Phospholipase D

Chunbo Qin, Weiqi Li, Yueyun Hong, Wenhua Zhang et autres

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