Johanna McChord

Age-independent prevalence of coronary vasomotor disorders in ANOCA/INOCA patients: a cross-sectional analysis of coronary aging effects

Johanna McChord, Astrid Hubert, Leonie Saccardi, A Seitz et autres

Abstract Background/Introduction Vascular aging contributes to structural and functional changes across various organs, including the heart. In patients with angina and no obstructive coronary artery disease (ANOCA/INOCA), coronary vasomotor disorders potentially causing angina pectoris may be attributed to coronary aging. However, the …

de (code pays fourni par la source)

Coronary Endothelial Dysfunction: Diagnostic Necessity or Futile Effort in Patients With Non‐Obstructive Angina?

Johanna McChord, Astrid Hubert, Leonie Saccardi, Andreas Seitz et autres

BACKGROUND: Angina in the absence of stenosing coronary artery disease (ANOCA) is a common yet challenging condition often linked to endothelial dysfunction (ED), coronary microvascular dysfunction (CMD), and coronary spasm. ED is defined as a coronary blood flow (CBF) increase of < …

de (code pays fourni par la source)

Bridging the Gender Gap in Cardiovascular Medicine: Addressing Drug Intolerances and Personalized Care for Women with Angina/Ischemia with Non-Obstructive Coronary Artery Disease

Johanna McChord

Gender medicine has increasingly underscored the necessity of addressing sex-based differences in disease prevalence and management, particularly within cardiovascular conditions and drug intolerance. Women often present cardiovascular diseases distinctively from men, with a higher prevalence of non-obstructive coronary artery disease and varied …

de (code pays fourni par la source)

Abstract 4120805: Comparison of Thermodilution and Doppler Flow Velocity Derived Indexes of Coronary Physiology using Intracoronary Adenosine in Patients with Angina and Unobstructed Coronary Arteries (ANOCA)

Louisa Lauinger, Astrid Hubert, Andreas Seitz, Raffi Bekeredjian et autres

Introduction: Patients with angina but unobstructed coronaries (ANOCA) represent a diagnostic and therapeutic challenge. Current Guidelines recommend invasive testing using acetylcholine and adenosine for evaluation of coronary vasomotor disorders. However, there is a broad variability among the different measurement techniques. Purpose: To …

de (code pays fourni par la source)

Diagnostic Yield of Comprehensive Coronary Function Testing in Patients with Angina and Unobstructed Coronary Arteries: Endotype Characterisation and Clinical Implications

Johanna McChord, Astrid Hubert, Raffi Bekeredjian, Peter Ong et autres

Background: Coronary functional disorders (CFD) are significant contributors to angina with non-obstructed coronary arteries (ANOCA). Various endotypes, such as epicardial or microvascular spasm and/or coronary microvascular dysfunction (CMD), have been identified. Previous studies have shown a high prevalence of CFD in ANOCA …

de (code pays fourni par la source)

Association of BMI, lipid-lowering medication, and age with prevalence of type 2 diabetes in adults with heterozygous familial hypercholesterolaemia: a worldwide cross-sectional study

Amany Elshorbagy, Alexander R.M. Lyons, Antonio J. Vallejo‐Vaz, Christophe Stevens et autres

BACKGROUND: Statins are the cornerstone treatment for patients with heterozygous familial hypercholesterolaemia but research suggests it could increase the risk of type 2 diabetes in the general population. A low prevalence of type 2 diabetes was reported in some familial hypercholesterolaemia cohorts, …

us (code pays fourni par la source)

New avenues for the assessment of stable ischemic heart disease

Johanna McChord, Valeria Martínez Pereyra, Udo Sechtem, Raffi Bekeredjian et autres

de (code pays fourni par la source)

Advancing precision medicine in INOCA research: The INOCA-IT registry

Johanna McChord

de (code pays fourni par la source)

Drug repurposing—a promising approach for patients with angina but non-obstructive coronary artery disease (ANOCA)

Johanna McChord, Valeria Martínez Pereyra, Sarah Froebel, Raffi Bekeredjian et autres

In today's era of individualized precision medicine drug repurposing represents a promising approach to offer patients fast access to novel treatments. Apart from drug repurposing in cancer treatments, cardiovascular pharmacology is another attractive field for this approach. Patients with angina pectoris without …

de (code pays fourni par la source)

Characterization and implications of intracoronary hemodynamic assessment during coronary spasm provocation testing

Andreas Seitz, Valeria Martínez Pereyra, Sarah Froebel, Astrid Hubert et autres

de (code pays fourni par la source)

Usefulness of wearable electrocardiography devices in patients experiencing paroxysmal cardiac-related symptoms: A case series of the “CardioSecur” system

Johanna McChord, Cathrin Theis, Sarah Fröbel, Andreas Seitz et autres

Background: Electrocardiograms (ECGs) recorded with wearable devices and additional smartphone apps play an increasing role in cardiology. Case summaries: We present two cases in which it was possible to record an ECG during cardiac-related symptoms using the patients' smartphones. Previous standard resting …

de (code pays fourni par la source)

Use of pharmacology in the diagnosis and management of vasomotor and microcirculation disorders

Johanna McChord, Peter Ong

de (code pays fourni par la source)