Giuseppe Genovesi

Deranged Dimensionality of Vestibular Re-Weighting in Multiple Chemical Sensitivity

Alessandro Micarelli, Andrea Viziano, Elisa Micarelli, Giuseppe Genovesi et autres

Background: Multiple chemical sensitivity (MCS) is a chronic multisystem condition characterized by low levels of multiple chemical susceptibility inducing a spectrum of central nervous system symptoms, including dizziness. Thus, considering (i) the overlapping psychogenic and organic burdens shared in MCS development and …

it (code pays fourni par la source)

Lack of contralateral suppression in transient-evoked otoacoustic emissions in multiple chemical sensitivity: a clinical correlation study

Andrea Viziano, Alessandro Micarelli, Giuseppe Genovesi, Ernesto Bruno et autres

Multiple chemical sensitivity (MCS) is a chronic disorder characterized by a variety of symptoms associated with the exposure to chemicals at a concentration below the toxic level. Previous studies have demonstrated peculiar responses in brain activity in these patients with respect to …

it (code pays fourni par la source)

Involvement of Subcortical Brain Structures During Olfactory Stimulation in Multiple Chemical Sensitivity

Marco Alessandrini, Alessandro Micarelli, Agostino Chiaravalloti, Ernesto Bruno et autres

Multiple chemical sensitivity (MCS) patients usually react to odour compounds and the majority of neuroimaging studies assessed, especially at the cortical level, many olfactory-related correlates. The purpose of the present study was to depict sub-cortical metabolic changes during a neutral (NC) and …

it, se (code pays fourni par la source)

Cortical activity during olfactory stimulation in multiple chemical sensitivity: a 18F-FDG PET/CT study

Agostino Chiaravalloti, Marco Pagani, Alessandro Micarelli, Barbara Di Pietro et autres

PURPOSE: To investigate the differences in brain glucose consumption during olfactory stimulation between subjects affected by multiple chemical sensitivity (MCS) and a group of healthy individuals. METHODS: Two (18)F-FDG PET/CT scans were performed in 26 subjects (6 men and 20 women; mean …

it, se (code pays fourni par la source)

Intranasal Administration of Hyaluronan as a Further Resource in Olfactory Performance in Multiple Chemical Sensitivity Syndrome

Marco Alessandrini, Alessandro Micarelli, E Bruno, Francesco Ottaviani et autres

Multiple chemical sensitivity (MCS) is a relatively common clinical diagnosis in western populations and its symptoms (i.e. dysosmia) are mainly triggered by chemical compounds, such as common odorants. The aim of this study was to test the effect of intranasal administration of …

it (code pays fourni par la source)

Obesity and Metabolic Comorbidities: Environmental Diseases?

Carla Lubrano, Giuseppe Genovesi, Palma Specchia, Daniela Costantini et autres

Obesity and metabolic comorbidities represent increasing health problems. Endocrine disrupting compounds (EDCs) are exogenous agents that change endocrine function and cause adverse health effects. Most EDCs are synthetic chemicals; some are natural food components as phytoestrogens. People are exposed to complex mixtures …

it (code pays fourni par la source)

Relationships between Body Fat Distribution, Epicardial Fat and Obstructive Sleep Apnea in Obese Patients with and without Metabolic Syndrome

Carla Lubrano, Maurizio Saponara, Giuseppe Bárbaro, Palma Specchia et autres

BACKGROUND: Obstructive sleep apnea (OSA) and metabolic syndrome, both closely related to obesity, often coexist in affected individuals; however, body mass index is not an accurate indicator of body fat and thus is not a good predictor of OSA and other comorbidities. …

it (code pays fourni par la source)

From microtubules to consciousness

Giuseppe Genovesi

it (code pays fourni par la source)

Idiopathic environmental intolerances (IEI): from molecular epidemiology to molecular medicine.

Chiara De Luca, Gabriella Maria Scordo, Eleonora Cesareo, Desanka Raskovic et autres

Inherited or acquired impairment of xenobiotics metabolism is a postulated mechanism underlying environment-associated pathologies such as multiple chemical sensitivity, fibromyalgia, chronic fatigue syndrome, dental amalgam disease, and others, also collectively named idiopathic environmental intolerances (IEI). In view of the poor current knowledge …

it, se (code pays fourni par la source)

Biological definition of multiple chemical sensitivity from redox state and cytokine profiling and not from polymorphisms of xenobiotic-metabolizing enzymes

Chiara De Luca, Maria Gabriella Scordo, Eleonora Cesareo, Saveria Pastore et autres

it, se, kr (code pays fourni par la source)

Metabolic or bariatric surgery? Long-term effects of malabsorptive vs restrictive bariatric techniques on body composition and cardiometabolic risk factors

Carla Lubrano, Stefania Mariani, Marco Badiali, Massimo Cuzzolaro et autres

it (code pays fourni par la source)

Physiopathology of the renin-angiotensin system in the ovary.

Francesco De Nuccio, Gabriele Salvati, Giuseppe Genovesi, Paul J. Paolini et autres

The present review confirms the existence of the so-called "ovarian-derived prorenin-angiotensin cascade". It also describes the physiopathology of the system and, consequently, its role in the genesis of phenomena concerning reproductive function such as ovulation, steroid synthesis and folliculogenesis. Moreover, the "ovarian-derived …

it (code pays fourni par la source)