James O. Robinson

Disseminated Lomentospora prolificans infection in a patient with neutropenia treated with ipilimumab and nivolumab

Nicholas William Dunstan, James O. Robinson, Andrew Walczak, Ammie Higgins et autres

Immune checkpoint inhibitor immunotherapy enhances T cell activity against cancer cells but often leads to the immune system targeting healthy cells, causing ‘immune-related adverse events’ (irAEs). We report the case of a man in his 70s with metastatic melanoma being treated with …

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Mental Health and Cultural Barriers in Collegiate Sport: A Cross-National Mixed Methods Study of U.S. and South Korean Collegiate Athletes

Joonyoung Lee, Jungyoun Kim, James O. Robinson, Jung Hoon Huh

Research on collegiate athlete mental health is overwhelmingly Western-centric, leaving a critical gap in understanding how cultural context shapes athletes’ experiences. This study addresses this gap through a cross-national comparison of the United States and South Korea. This convergent mixed-methods study integrated …

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Safety and Efficacy of MV140 Sublingual Vaccine (Uromune) in Preventing Recurrent Urine Infections Post Renal Transplant: A Case Series

Benjamin Palladino, Devin O'Shea‐Farren, Peter Boan, Sharon Ho et autres

The authors declare no conflicts of interest. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the …

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Adherence to Quality-of-Care Indicators and Mortality Outcomes in Patients With MRSA Bacteremia: A Post Hoc Analysis of the CAMERA2 Randomized Clinical Trial.

I. Russel Lee, Yanan Zhu, Neela Joshi, Matthew O’Sullivan et autres

Importance: Adherence to quality-of-care indictors (QCIs) is associated with better Staphylococcus aureus bacteremia (SAB) outcomes. It is unknown whether clinical trial participation adventitiously improves QCI adherence and clinical outcomes compared with nontrial routine care for SAB. Objective: To evaluate whether health care …

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Short course antiviral therapy to prevent donor‐derived hepatitis C virus infection

Peter Boan, Kate Proudmore, Ashley Irish, Jagadish Jamboti et autres

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Association of Daily Body Temperature, White Blood Cell Count, and C-reactive Protein With Mortality and Persistent Bacteremia in Patients With Staphylococcus Aureus Bacteremia: A Post Hoc Analysis of the CAMERA2 Randomized Clinical Trial

Sean Wei Xiang Ong, Nick Daneman, Joshua S. Davis, Steven Y. C. Tong et autres

Abstract Introduction Classification of patients with Staphylococcus aureus bacteremia as complicated versus uncomplicated is based on a combination of clinical and microbiologic variables. Whether daily body temperature and common laboratory tests such as C-reactive protein (CRP) and white blood cell (WBC) can …

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A Phase 1/2 Study of a ROR1-Targeting CAR T Cell Therapy (ONCT-808) in Adult Patients with Relapsed/Refractory (R/R) Aggressive B Cell Lymphomas (BCL)

Michael Wang, P. Connor Johnson, Salim Yazji, Yisrael Katz et autres

INTRODUCTION ROR1 is an oncoembryonic pseudo-tyrosine kinase receptor expressed on malignant cells across a variety of hematologic and solid malignancies. As such, ROR1 is an ideal therapeutic target with potential for maximizing on-target anti-tumor activity while minimizing off-target toxicity. ONCT-808 utilizes a …

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Body Mass Index as a Determinant of Lower Limb Function and Community Well-Being in Older Adults: Analysis of 2020 National Older Korean Survey Data

Joonyoung Lee, James O. Robinson, Jung Hun Huh, Eunseong Kim

This epidemiological research investigated the relationship between body mass index (BMI) and lower limb function and community well-being among the older population (≥65 years old) in South Korea. Using the 2020 National Survey of Older Koreans (N = 10 097; M age …

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Infective endocarditis outcomes at a tertiary hospital in Western Australia: a retrospective cohort study from 2016 to 2021

E. K. Lawson, Angela Jacques, Claire M. Italiano, James O. Robinson

BACKGROUND: Infective endocarditis (IE) is a severe infection with considerable mortality. It is associated with geographical variation, complicating diagnosis and treatment of patients in a standardised manner. AIM: To evaluate the characteristics and management outcomes of patients with IE in Royal Perth …

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Genomic investigation and clinical correlates of the in vitro β-lactam: NaHCO 3 responsiveness phenotype among methicillin-resistant Staphylococcus aureus isolates from a randomized clinical trial

Neta Petersiel, Stefano Giulieri, Diane Daniel, Sook‐Ha Fan et autres

ABSTRACT NaHCO 3 responsiveness is a novel phenotype where some methicillin-resistant Staphylococcus aureus (MRSA) isolates exhibit significantly lower minimal inhibitory concentrations (MIC) to oxacillin and/or cefazolin in the presence of NaHCO 3 . NaHCO 3 responsiveness correlated with treatment response to β-lactams …

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Does Adjunctive Clindamycin Have a Role in Staphylococcus aureus Bacteremia? A Protocol for the Adjunctive Treatment Domain of the Staphylococcus aureus Network Adaptive Platform (SNAP) Randomized Controlled Trial

Keerthi Anpalagan, Ravindra Dotel, Derek R. MacFadden, Simon Smith et autres

BACKGROUND: The use of adjunctive antibiotics directed against exotoxin production in Staphylococcus aureus bacteremia (SAB) is widespread, and it is recommended in many guidelines, but this is based on limited evidence. Existing guidelines are based on the theoretical premise of toxin suppression, …

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3185: Retrospective analysis of output data for ten linear accelerators at Northern Ireland Cancer Centre

Hannah Marshall, James O. Robinson, R B King, Conor K. McGarry et autres