Erdal Sönmez

Synthesis and Characterization of Memantine-Loaded Niosomes for Enhanced Alzheimer’s Disease Targeting

Hasan Türkez, Sena Öner, Özge Çağlar, Mehmet Enes Arslan et autres

Background/Objectives: Over the past 25 years, numerous biological molecules, like recombinant lysosomal enzymes, neurotrophins, receptors, and therapeutic antibodies, have been tested in clinical trials for neurological diseases. However, achieving significant success in clinical applications has remained elusive. A primary challenge has been …

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In Vitro Transcriptome Analysis of Cobalt Boride Nanoparticles on Human Pulmonary Alveolar Cells

Mehmet Enes Arslan, Arzu Tatar, Özge Çağlar, İrfan Oğuz Şahin et autres

Nanobiotechnology influences many different areas, including the medical, food, energy, clothing, and cosmetics industries. Considering the wide usage of nanomaterials, it is necessary to investigate the toxicity potentials of specific nanosized molecules. Boron-containing nanoparticles (NPs) are attracting much interest from scientists due …

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Ameliorative Effects by Hexagonal Boron Nitride Nanoparticles against Beta Amyloid Induced Neurotoxicity

Nursah Aydin, Hasan Türkez, Özlem Özdemir Tozlu, Mehmet Enes Arslan et autres

Alzheimer’s disease (AD) is considered as the most common neurodegenerative disease. Extracellular amyloid beta (Aβ) deposition is a hallmark of AD. The options based on degradation and clearance of Aβ are preferred as promising therapeutic strategies for AD. Interestingly, recent findings indicate …

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Molecular Genetics and Cytotoxic Responses to Titanium Diboride and Zinc Borate Nanoparticles on Cultured Human Primary Alveolar Epithelial Cells

Hasan Türkez, Mehmet Enes Arslan, Arzu Tatar, Özlem Özdemir Tozlu et autres

Titanium diboride (TiB2) and zinc borate (Zn3BO6) have been utilized in wide spectrum industrial areas because of their favorable properties such as a high melting point, good wear resistance, high hardness and thermal conductivity. On the other hand, the biomedical potentials of …

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Investigating the Effect of Yttrium Oxide Nanoparticle in U87MG Glioma and PC3 Prostate Cancer: Molecular Approaches

Elanur Aydın Karataş, Kübra BAYINDIRLI, Özlem Özdemir Tozlu, Erdal Sönmez et autres

Yttrium oxide (Y2O3) nanoparticles have very wide application areas such as biological imaging, photodynamic therapy, the material sciences, in the chemical synthesis of inorganic compounds, additives in plastic, paint, steel, optics, and iron. Potential risks to human health and the environment should …

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Safety Assessments of Nickel Boride Nanoparticles on the Human Pulmonary Alveolar Cells by Using Cell Viability and Gene Expression Analyses

Hasan Türkez, Mehmet Enes Arslan, Erdal Sönmez, Abdülgani Tatar et autres

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Expression profiling and pathway analysis of iron oxide nanoparticles toxicity on human lung alveolar epithelial cell line using microarray analysis

Hasan Türkez, Mehmet Enes Arslan, Erdal Sönmez, Abdülgani Tatar et autres

Toxicogenomics is a developing area searching for cellular pathways and mechanisms including cancer, immunological diseases, environmental responses, gene-gene interactions and drug toxicity. Nanoparticles (NPs) become important candidates for analyzing in toxicogenomic experiments because of their unusual properties in various biological activities. Therefore, …

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Effect of in-/ex-situ annealing temperature on the optical, structural and gas sensing dynamics of CdS nanostructured thin films

Arife Efe Görmez, Mohamed A. Basyooni, Shrouk E. Zaki, Yasin Ramazan Eker et autres

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Neuroprotective effects of boron nitride nanoparticles in the experimental Parkinson’s disease model against MPP+ induced apoptosis

Recep Küçükdoğru, Hasan Türkez, Mehmet Enes Arslan, Özlem Özdemir Tozlu et autres

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Europium incorporation dynamics within NiO films deposited by sol-gel spin coating: Experimental and theoretical studies

Souraya Goumri‐Said, Wilayat Khan, Karem Boubaker, Güven Turgut et autres

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Microarray assisted toxicological investigations of boron carbide nanoparticles on human primary alveolar epithelial cells

Hasan Türkez, Mehmet Enes Arslan, Erdal Sönmez, Fatime Geyikoğlu et autres

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Synthesis, characterization and cytotoxicity of boron nitride nanoparticles: emphasis on toxicogenomics

Hasan Türkez, Mehmet Enes Arslan, Erdal Sönmez, Metin Açıkyıldız et autres

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