Roberto Lorbeer

Long-term exposure of physical inactivity and MRI-derived left ventricular myocardial Function: Results from a population-based cohort

P. Franke, Thomas Geyer, Sophia Stöcklein, Olaf Dietrich et autres

OBJECTIVE: The association of physical inactivity with subclinical alteration of cardiac structure and function is not well established. In the present study, we investigated this association with left-ventricular (LV) function assessed by advanced MRI strain analysis in a population-based cohort free of …

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Validation of AI-derived whole prostate volumetry versus ellipsoid formula for PSA density-based risk stratification

Hüdanur Bayraktaroglu, Maurice M. Heimer, J.Felix Kuhnle, Roberto Lorbeer et autres

PURPOSE: State-of-the-art AI tools offer automated prostate MR volumetry, potentially improving accuracy and efficiency compared to approximation using the ellipsoid formula (A x P x L x 0.52). However, data on the clinical validity of AI-derived volumetry (AI-V) for PSA density (PSAD)-based …

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Sex-Specific Patterns of Left Ventricular Remodeling Using Regional Wall Thickness Data and Their Associations with Cardiovascular Disease Risk

Susanne Rospleszcz, Till Ittermann, Margarethe Woeckel, Sabine Schipf et autres

Abstract Background Left ventricular (LV) remodeling is associated with impaired cardiac function and future cardiovascular disease (CVD). Current remodeling definitions use broad categorizations based on hypertrophy and mean wall thickness. Cardiac magnetic resonance (CMR) imaging provides detailed characterization of regional myocardial wall …

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Intra- and inter-field strength reproducibility of deep-learning based real-time cardiac MRI cine sequences with breath hold and in free breathing

Lena‐Maria Watzke, Ann‐Christin Klemenz, Karolin K. Deyerberg, Benjamin Böttcher et autres

To assess intra- and inter-field strength reproducibility of volumetric parameters using deep-learning-based real-time cardiac cine MRI during breath-hold (BH) and free-breathing (FB). In this prospective single-center study, 56 healthy adults underwent cardiac MRI at 1.5 T. Of these, 33 had a follow-up …

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Long-term effect of physical inactivity on osteosarcopenic obesity – a MRI-based investigation from a population-based cohort

Lena S. Kiefer, Roberto Lorbeer, Susanne Rospleszcz, Wolfgang Rathmann et autres

BACKGROUND: The hazardous triad of osteopenia, sarcopenia and obesity was recently defined as osteosarcopenic obesity (OSO). The causes for OSO appear to be multifactorial, including age and gender, as well as chronic diseases. The impact of physical inactivity has not been studied …

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Pushing the limits of cardiac MRI: deep-learning based real-time cine imaging in free breathing vs breath hold

Ann‐Christin Klemenz, Lena‐Maria Watzke, Karolin K. Deyerberg, Benjamin Böttcher et autres

OBJECTIVE: To evaluate deep-learning (DL) based real-time cardiac cine sequences acquired in free breathing (FB) vs breath hold (BH). MATERIALS AND METHODS: In this prospective single-centre cohort study, 56 healthy adult volunteers were investigated on a 1.5-T MRI scanner. A set of …

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Association of long-term physical inactivity with left ventricular function assessed by MRI derived myocardial 2D strain in a population-based cohort

Roberto Lorbeer, P. Franke, Thomas Geyer, Sophia Stoecklein et autres

Abstract Background The association of physical inactivity with subclinical alteration of cardiac structure and function is not well studied. In the present study, we investigated the association of physical inactivity with left-ventricular function assessed by advanced MRI strain analysis in a population-based …

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Coordinating Multicenter Research during a Pandemic: Ethical and Operational Lessons from the German NAPKON Initiative

Katharina Tilch, Sina M. Pütz, Lazar Mitrov, Melanie Stecher et autres

Accelerated Cardiac MRI with Deep Learning–based Image Reconstruction for Cine Imaging

Ann‐Christin Klemenz, Linda Reichardt, Margarita Gorodezky, Mathias Manzke et autres

Deep learning–based cardiac cine sequences performed over three cardiac cycles led to substantially reduced acquisition time, while no differences in image quality and volumetric results compared with a standard clinical sequence could be detected.

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Subclinical impairment of the left atrium is associated with MRI-based lung volume but not with parameters from pulmonary function testing

Charlotte Wintergerst, Roberto Lorbeer, Blerim Mujaj, Bernard E. Bulwer et autres

Abstract Left atrial (LA) physiology and hemodynamics are intimately connected to cardiac and lung function in health and disease. This study examined the relationship between MRI-based left atrial (LA) size and function with MRI-based lung volume and pulmonary function testing (PFT) parameters …

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Association of aortic diameters and mortality in the general population—an MRI-based study

Birger Mensel, Andreas H. Mahnken, Erhard Kaiser, Henry Völzke et autres

BACKGROUND: Increased diameters of the aorta are associated with increased mortality risk. In the present analyses, we assessed whether aortic diameters are associated with cardiovascular and all-cause mortality in community-dwelling individuals free of known cardiovascular disease (CVD). METHODS: MRI-derived vascular parameters of …

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Associations between adrenal gland volume and adipose tissue compartments – a whole body MRI study

Esther Askani, Susanne Rospleszcz, Roberto Lorbeer, Charlotte Wintergerst et autres

BACKGROUND: Obesity is associated with alterations in the hypothalamic-pituitary-adrenal (HPA) axis. Effects of glucocorticoids on adipose tissues appear to depend on the specific adipose depot, in which they take place. In this study, we aimed to investigate the role of MRI-based adrenal …

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