Kristin Öhlinger

Force Spectroscopy by Atomic Force Microscopy as Indicator for Cellular Microplastic Uptake

Tatjana Kolesnik, Kristin Öhlinger, Markus Absenger‐Novak, Eleonore Fröhlich

Concentrations of microplastic particles (MPs) in the environment are low, and cellular uptake is difficult to measure. Cancer tissue accumulates more MPs than normal tissue. This study aims to determine whether cellular stiffness measurements by atomic force microscopy could indicate whether cells …

at (code pays fourni par la source)

Skin Sensitization Potential of Sensitizers in the Presence of Metal Oxide Nanoparticles In Vitro

Claudia Meindl, Kristin Öhlinger, Verena Zrim, Jennifer Ober et autres

Silica (SiO2), titanium dioxide (TiO2), and zinc oxide (ZnO) nanoparticles (NPs) are widely used in dermal products. Their skin sensitization potential, especially their effects in combination with known sensitizers, is poorly studied in vitro and their sensitization inconsistently reported in animal studies. …

at (code pays fourni par la source)

Lipid-based particle engineering via spray-drying for targeted delivery of antibiotics to the lung

Carolina Corzo, Djana Crvenjak, Kamen Sotirov, Jesús Alberto Afonso Urich et autres

at (code pays fourni par la source)

Screening for Effects of Inhaled Nanoparticles in Cell Culture Models for Prolonged Exposure

Claudia Meindl, Kristin Öhlinger, Verena Zrim, Thomas Steinkogler et autres

Respiratory exposure of humans to environmental and therapeutic nanoparticles repeatedly occurs at relatively low concentrations. To identify adverse effects of particle accumulation under realistic conditions, monocultures of Calu-3 and A549 cells and co-cultures of A549 and THP-1 macrophages in the air–liquid interphase …

at (code pays fourni par la source)

Different Sensitivity of Macrophages to Phospholipidosis Induction by Amphiphilic Cationic Drugs

Kristin Öhlinger, Markus Absenger‐Novak, Claudia Meindl, Jennifer Ober et autres

Phospholipidosis (PLD), the intracellular accumulation of phospholipids, is an adaptive response to toxic stimuli and serves as an important parameter in the biological assessment of compounds. Cationic amphiphilic drugs are the main inducers of PLD and may impair the function of alveolar …

at (code pays fourni par la source)

In vitro toxicity screening of polyglycerol esters of fatty acids as excipients for pulmonary formulations

Eleonore Fröhlich, Kristin Öhlinger, Claudia Meindl, Carolina Corzo et autres

at (code pays fourni par la source)

Cytotoxicity screening of emulsifiers for pulmonary application of lipid nanoparticles

Verena Steiner, Kristin Öhlinger, Carolina Corzo, Sharareh Salar-Behzadi et autres

at (code pays fourni par la source)

Air-liquid interface culture changes surface properties of A549 cells

Kristin Öhlinger, Tatjana Kolesnik, Claudia Meindl, Birgit Gallé et autres

at (code pays fourni par la source)

Are in vivo and in vitro assessments of comparative and combined toxicity of the same metallic nanoparticles compatible, or contradictory, or both? A juxtaposition of data obtained in respective experiments with NiO and Mn3O4 nanoparticles

Ilzira A. Minigalieva, Tatiana V. Bushueva, Eleonore Fröhlich, Claudia Meindl et autres

ru, at (code pays fourni par la source)

Comparison of fluorescence-based methods to determine nanoparticle uptake by phagocytes and non-phagocytic cells in vitro

Claudia Meindl, Kristin Öhlinger, Jennifer Ober, Eva Roblegg et autres

At many portals of entry the relative uptake by phagocytes and non-phagocytic cells has a prominent effect on availability and biological action of nanoparticles (NPs). Cellular uptake can be determined for fluorescence-labeled NPs. The present study compares three methods (plate reader, flow …

at (code pays fourni par la source)