Xianghe Jiang

Environmentally Responsive Catalytic Microneedles Enable Cascade Fenton Reaction for Antibacterial Therapy and Accelerated Infected Wound Healing

Yongjie Cai, Xianghe Jiang, Yuemin Wang, F. X. Li et autres

ABSTRACT The persistence of bacterial biofilms and resistance limits the efficacy of traditional therapies, slowing tissue regeneration. Here, we report an innovative pH‐responsive catalytic microneedle system (GZIF@Fe MN) designed to combat bacterial infections by disrupting bacterial redox homeostasis through a cascade Fenton …

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Hybrid hydrogels of polysaccharides and inorganic nanomaterials: A synergistic combat-engine for drug delivery and tissue regeneration

Mengya Zhang, Yufei Ren, Xianghe Jiang, Cuimin Chen et autres

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PD-L1 siRNA incorporation into a cationic liposomal tumor mRNA vaccine enhances cytotoxic T cell activation and prevents immune evasion

Jingsheng Zhou, Yuanyuan Li, Xianghe Jiang, Zhongyuan Xin et autres

T cells. Furthermore, cationic liposomes play dual roles as carriers crucial for preserving the integrity of nucleic acids for antigen translation and as inhibitors of autophagy-a process essential for both promoting antigen cross-presentation and revitalizing MHC-I expression on tumor cells, thereby increasing …

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MoS 2 Nanozyme–Chlorella Hydrogels: Pioneering a Hepatocellular Carcinoma Integrative Therapy

Mengya Zhang, Jingsheng Zhou, Xianghe Jiang, Te Shi et autres

Abstract Hepatocellular carcinoma (HCC) poses a formidable challenge to global health, and surgical resection is the predominant therapeutic strategy. However, the efficacy of postoperative adjuvant treatments is often compromised by the need to preserve liver function. The authors’ meta‐analysis reveals a significant …

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Modulating autophagy in the tumor microenvironment with a salinomycin-loaded liposome hybrid nanovesicle system for tumor immunotherapy

Xinying Li, Wenshang Liu, Zhenzhen Yan, Xianghe Jiang et autres

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Nanomaterials for Combating Cancer while Safeguarding Organs: Safe and Effective Integrative Tumor Therapy

Keqin Ji, Xianghe Jiang, Zhuanzhuan Zhang, Mengfan Li et autres

Cancer remains a leading cause of mortality globally. Combating cancer while safeguarding organs (CCSO) has emerged as a specialized field that employs a multifaceted approach to cancer management. Postsurgery solid tumors face issues such as recurrence and organ dysfunction due to residual …

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ROS-sensitive PD-L1 siRNA cationic selenide nanogels for self-inhibition of autophagy and prevention of immune escape

Jie Gao, Yonghua Zhai, Weihong Lu, Xianghe Jiang et autres

/siPD-L1 nanogels showed synergistic antitumor efficacy through self-inhibition of autophagy and prevention of immune escape.

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Integrated Copper Nanomaterials‐Decorated Microsphere Photothermal Platform for Comprehensive Melanoma Treatment

Xinyi Zhang, Mengya Zhang, Hengqing Cui, Tinglin Zhang et autres

Melanoma Treatment In article number 2400028, Jie Gao and co-workers present an innovative copper nanomaterial-decorated microsphere photothermal platform consisting of PLGA/PDA microspheres and HKUST-1, coated with tumor cell membranes. The PLGA/PDA-CCM’s versatility combines tumor elimination, recurrence prevention, and wound healing, presenting a …

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Integrated Copper Nanomaterials‐Decorated Microsphere Photothermal Platform for Comprehensive Melanoma Treatment

Xinyi Christine Zhang, Mengya Zhang, Hengqing Cui, Tinglin Zhang et autres

Patients who undergo resection for melanoma face challenges, such as delayed healing and radiation dermatitis. Moreover, incomplete tumor resection is a key factor contributing to poor prognosis and increased recurrence rates. However, a therapeutic platform that can effectively prevent tumor recurrence and …

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Application of nanostructure-loaded hydrogels for cancer treatment and tissue regeneration

Yufei Ren, Cuimin Chen, Mengya Zhang, Xiuwen Ding et autres

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List of contributors

Moustafa M. Abdelaziz, Manar Abdelhalem, Mariam Khaled Abdel‐Latif, Mahmoud M. Abdullah et autres

us, Égypte, bd, in, ir, ae, cn, br (code pays fourni par la source)

Biomembrane-based nanoparticles for cancer immunotherapy

Xianghe Jiang, Lili Wu, Mengya Zhang, Tinglin Zhang et autres

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