Dina Fathalla

Comprehensive lipidomics of tissue macrophages reveal LTE4–driven eosinophil survival

Magdalena A. Czubala, Patricia Rodrigues, Natacha Ipseiz, Marcela Rosas et autres

Tissue-resident peritoneal macrophages (pMФ) programmed by GATA6 are essential players regulating immunity and tissue balance in the peritoneal cavity. How GATA6 regulates global lipid metabolism is currently unknown. Addressing this, in myeloid-restricted Gata6-deficient (Gata6-KOmye) mice, significant changes to the pMФ lipidome were …

ca, gb (code pays fourni par la source)

Reviewer #1 (Public review): Comprehensive lipidomics of tissue macrophages reveal LTE4–driven eosinophil survival

Magdalena A. Czubala, Patricia Rodrigues, Natacha Ipseiz, Marcela Rosas et autres

Tissue-resident peritoneal macrophages (pMФ) programmed by GATA6 are essential players regulating immunity and tissue balance in the peritoneal cavity. How GATA6 regulates global lipid metabolism is currently unknown. Addressing this, in myeloid-restricted Gata6-deficient (Gata6-KOmye) mice, significant changes to the pMФ lipidome were …

Reviewer #2 (Public review): Comprehensive lipidomics of tissue macrophages reveal LTE4–driven eosinophil survival

Magdalena A. Czubala, Patricia Rodrigues, Natacha Ipseiz, Marcela Rosas et autres

Tissue-resident peritoneal macrophages (pMФ) programmed by GATA6 are essential players regulating immunity and tissue balance in the peritoneal cavity. How GATA6 regulates global lipid metabolism is currently unknown. Addressing this, in myeloid-restricted Gata6-deficient (Gata6-KOmye) mice, significant changes to the pMФ lipidome were …

Reviewer #3 (Public review): Comprehensive lipidomics of tissue macrophages reveal LTE4–driven eosinophil survival

Magdalena A. Czubala, Patricia Rodrigues, Natacha Ipseiz, Marcela Rosas et autres

Tissue-resident peritoneal macrophages (pMФ) programmed by GATA6 are essential players regulating immunity and tissue balance in the peritoneal cavity. How GATA6 regulates global lipid metabolism is currently unknown. Addressing this, in myeloid-restricted Gata6-deficient (Gata6-KOmye) mice, significant changes to the pMФ lipidome were …

Author response: Comprehensive lipidomics of tissue macrophages reveal LTE4–driven eosinophil survival

Magdalena A. Czubala, Patricia Rodrigues, Natacha Ipseiz, Marcela Rosas et autres

Tissue-resident peritoneal macrophages (pMФ) programmed by GATA6 are essential players regulating immunity and tissue balance in the peritoneal cavity. How GATA6 regulates global lipid metabolism is currently unknown. Addressing this, in myeloid-restricted Gata6-deficient (Gata6-KOmye) mice, significant changes to the pMФ lipidome were …

Comprehensive lipidomics of tissue macrophages reveal LTE4–driven eosinophil survival

Magdalena A. Czubala, Patricia Rodrigues, Natacha Ipseiz, Marcela Rosas et autres

Tissue-resident peritoneal macrophages (pMФ) programmed by GATA6 are essential players regulating immunity and tissue balance in the peritoneal cavity. How GATA6 regulates global lipid metabolism is currently unknown. Addressing this, in myeloid-restricted Gata6-deficient (Gata6-KOmye) mice, significant changes to the pMФ lipidome were …

ca, gb (code pays fourni par la source)

Comprehensive lipidomics of tissue macrophages reveal LTE4–driven eosinophil survival

Magdalena A. Czubala, Patricia Rodrigues, Natacha Ipseiz, Marcela Rosas et autres

Abstract Tissue-resident peritoneal macrophages (pMФ) programmed by GATA6 are essential players regulating immunity and tissue balance in the peritoneal cavity. How GATA6 regulates global lipid metabolism is currently unknown. Addressing this, in myeloid-restricted Gata6 -deficient (G ata6 -KO mye ) mice, significant …

ca, gb (code pays fourni par la source)

DEVELOPMENT OF DEXAMETHASONE SODIUM PHOSPHATE –LOADED POLYMERIC NANOPARTICLES AS A DELIVERY SYSTEM FOR THE ANTERIOR SEGMENT OF THE EYE

RAWAN ALHEJJAWI, MOHAMED ATTIA SHAFIE, Dina Fathalla, RAWAND DAGHMASH

Objective: Uveitis is an inflammatory ocular disease that requires localized and sustained corticosteroid delivery to minimize systemic exposure and adverse effects. Conventional dexamethasone formulations are limited by poor corneal penetration, rapid precorneal clearance, and the need for frequent administration. This study aims …

Égypte, jo (code pays fourni par la source)

Design and Bioevaluation of Mizolastine Nanosponges for Management of Allergic Skin Conditions

Ahmed A. El-Shenawy, Reham A. Abd Elkarim, Dina Fathalla, Hanan A. Abd Elkarim et autres

Égypte, id (code pays fourni par la source)

Curcumin-loaded gold nanoparticles with enhanced antibacterial efficacy and wound healing properties in diabetic rats

Ayman Salama, Nehal M. Elsherbiny, ‏Helal F. Hetta, Mohamed A. Safwat et autres

sa, Égypte (code pays fourni par la source)

A green chemistry approach for preparation of metronidazole-zinc (ІІ) complexes: In vitro characterization, antimicrobial activity and promising cytotoxicity

Hebatallah B. Mohamed, Aml I. Mekkawy, Abdelhafeiz Mahmoud, Dina Fathalla et autres

Égypte (code pays fourni par la source)

Development and characterization of nanostructure lipid carrier for anti-hepatitis-C virus drug

Mahmoud El‐Badry, Ominia Mahmoud, Dina Fathalla, Gamal El-Gendy

Velpatasvir (VLP) as, a medication used to treat hepatitis-C virus (HCV). It has a very low oral bioavailability (25%). The aim of the current work is to prepare VLP loaded nanostructured lipid carriers (VLP-NLCs) as a potential way to enhance VLP aqueous …

Égypte (code pays fourni par la source)