Isabel Barriuso-Ortega

Research Agora: from hidden data to dynamic, reproducible knowledge

Isabel Barriuso-Ortega, Pablo Hernández-Malmierca

Publication bias and the reproducibility crisis are rooted in outdated evaluation practices and erode trust in science. Research assessment reform focuses on the quality and impact of research, as opposed to article counts and journal impact factors. Research Agora emerged as an …

Characterization of single neurons reprogrammed by pancreatic cancer

Vera Thiel, Simon Renders, Jasper Panten, Nicolas Dross et autres

. However, neuronal cell bodies reside in various PNS ganglia, far from the tumour mass. Thus, cancer-innervating or healthy-organ-innervating neurons are lacking in current tissue-sequencing datasets. To molecularly characterize pancreas- and PDAC-innervating neurons at single-cell resolution, we developed Trace-n-Seq. This method uses …

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Distinct spatial maps and multiple object codes in the lateral entorhinal cortex

Xu Huang, Magdalene Isabell Schlesiger, Isabel Barriuso-Ortega, Christian Leibold et autres

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Distinct spatial maps and multiple object codes in the lateral entorhinal cortex

Xu Huang, Magdalene Isabell Schlesger, Isabel Barriuso-Ortega, Christian Leibold et autres

Data used for the paper "Distinct spatial maps and multiple object codes in the lateral entorhinal cortex". For each open field trial of each recording session, there are two files ("sop" with spike times and x-y position of the mouse at that …

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Distinct spatial maps and multiple object codes in the lateral entorhinal cortex

Xu Huang, Magdalene Isabell Schlesger, Isabel Barriuso-Ortega, Christian Leibold et autres

Data used for the paper "Distinct spatial maps and multiple object codes in the lateral entorhinal cortex". For each open field trial of each recording session, there are two files ("sop" with spike times and x-y position of the mouse at that …

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Distinct spatial maps and multiple object codes in the lateral entorhinal cortex

Xu Huang, Magdalene Isabell Schlesiger, Isabel Barriuso-Ortega, Christian Leibold et autres

Summary The lateral entorhinal cortex (LEC) is a major cortical input area to the hippocampus and it is crucial for associative object-place-context memories. An unresolved question is whether these associations are performed exclusively in the hippocampus or also upstream thereof. Anatomical evidence …

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Two septal-entorhinal GABAergic projections differentially control coding properties of spatially tuned neurons in the medial entorhinal cortex

Magdalene Isabell Schlesiger, Tobias Ruff, Duncan A. A. MacLaren, Isabel Barriuso-Ortega et autres

Septal parvalbumin-expressing (PV + ) and calbindin-expressing (CB + ) projections inhibit low-threshold and fast-spiking interneurons, respectively, in the medial entorhinal cortex (MEC). We investigate how the two inputs control neuronal activity in the MEC in freely moving mice. Stimulation of PV …

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