Renzo Orlassino

Patient and Context Factors in the Adoption of Active Surveillance for Low-Risk Prostate Cancer

Giovannino Ciccone, Stefano De Luca, Marco Oderda, F. Muñoz et autres

Importance: Although active surveillance for patients with low-risk prostate cancer (LRPC) has been recommended for years, its adoption at the population level is often limited. Objective: To make active surveillance available for patients with LRPC using a research framework and to compare …

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Intussuscezione intestinale nell'adulto: una rara localizzazione di melanoma

Antonio Solazzo, Roberto Gallo, Amerigo Garigali, Giuseppina Girino et autres

The Dilemma of HER2 Double-equivocal Breast Carcinomas

Caterina Marchiò, Patrizia Dell’Orto, Laura Annaratone, Felipe C. Geyer et autres

The American Society of Clinical Oncology/College of American Pathologists (ASCO/CAP) 2013 guidelines for HER2 assessment have increased the number of HER2 equivocal breast carcinomas following in situ hybridization reflex testing, that is, HER2 "double equivocal" (equivocal protein expression and equivocal gene copy …

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Un caso di angiosarcoma polmonare e revisione della letteratura

Maria Chiara Todaro, Renzo Orlassino, Cristina Fornengo, Adriana Ravera et autres

L’angiosarcoma polmonare è un tumore altamente maligno e caratterizzato da una prognosi particolarmente infausta. Una diagnosi precoce seguita da una terapia chirurgica radicale rappresenta l’unica possibilità di sopravvivenza per i pazienti che ne sono affetti. Le manifestazioni cliniche subdole, così come i …

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Does accelerated hypofractionated adjuvant whole-breast radiotherapy increase mammographic density or change mammographic features?

Silvia Bagnera, L Milanesio, Piero B Brachet Cota, Carla Berrino et autres

OBJECTIVE: To compare mammographic features before and after accelerated hypofractionated adjuvant whole-breast radiotherapy (AWB-RT) and to evaluate possible appearance of modifications. METHODS: A retrospective review of 177 females before and after an AWB-RT treatment (follow-up ranging from 5 to 9 years) was …

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Gene Status in HER2 Equivocal Breast Carcinomas: Impact of Distinct Recommendations and Contribution of a Polymerase Chain Reaction-Based Method

Anna Sapino, Francesca Maletta, Ludovica Verdun di Cantogno, Luigia Macrì et autres

BACKGROUND: The primary objectives of this study on carcinomas with equivocal HER2 expression were to assess the impact of distinct recommendations with regard to identifying patients eligible for anti-HER2 agents by fluorescence in situ hybridization (FISH) and to elucidate whether multiplex ligation-dependent …

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New Wireless Handheld Ultrasound-Guided Vacuum-Assisted Breast Biopsy (VABB) Devices: An Important Innovation in Breast Diagnosis

Silvia Bagnera, Sebastiano Patania, L Milanesio, Giovanni Gatti et autres

Vacuum-assisted breast biopsy (VABB) plays a fundamental role in the preoperative assessment of breast lesions pro- viding large histology samples that are useful to define diagnoses and biological parameters to guide treatment planning. This technique has been used in our institute since …

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[Neurendocrine tumours of the appendix, colon and rectum: current surgical aspects].

L Rosato, De Tomaa G, Guido Mondini, Francesca Fornari et autres

Neuroendocrine tumours (NET) are a heterogeneous group of neoplasms deriving from a system of diffuse neuroendocrine cells in organs and tissues, defined as the "diffuse neuroendocrine system". Over the period from 1996 to 2005 42 patients with gastroenteropancreatic (GEP) NET were observed …

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[Intra-abdominal desmoid tumors: rare but important disease].

L Rosato, Guido Mondini, M Serbelloni, Patricia Bertone et autres

Desmoid tumors are rare benign neoplasms with high tendency to local recurrence, and they can be divided into extra- and intra-abdominal types (mesenteric fibromatosis). Eight cases have been treated in our Department from 1997 to 2006. Six patients (3 men and 3 …

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[Recurrent intraparenchimal haemorrhages in a patient with cerebral amyloidotic angiopathy: description of one autopsy case].

Camila de Barros Gallo, Renzo Orlassino, C Vineis

Cerebral amyloidotic angiopathy represents the most frequent cause of lobar haematoma in young patients and represents 5-10% of the non-traumatic cerebral haemorrhages. In the present work, we describe one autoptic case of recurrent cerebral haemorrhages in a 58-year-old woman. Macroscopically in the …

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[The use of a computerised system in the reading of cytological cervicovaginals smears during programming of regional screening (one year of experience using the autopap system)].

Renzo Orlassino, Tiziana Fabbrini, Ciro Gallo, C Vineis

From january to december 2001 n. 23.940 conventional Pap smears were consecuetively processed by the Autopap System. All these slides classified by AutoPap as "review" were subjected to a conventional reading by cytotechnologist using FOV areas selected by AUTOPAP and classified according …

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Extremely low frequency‐modulated static magnetic fields to treat cancer: A pilot study on patients with advanced neoplasm to assess safety and acute toxicity

F Ronchetto, Domenico Barone, Marcella Cintorino, Michele Berardelli et autres

Results of a toxicity pilot human study approved by the competent ethical Committee are reported. Eleven patients with heavily pre-treated advanced cancer were enrolled in a pilot study with different schedules of time exposure to static magnetic fields (MF), amplitude modulated by …

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