Stephanie Worrell

Association of resection type, nodal evaluation, and survival in early-stage lung squamous cell carcinoma

Evelyn Alexander, Titilope Sandra Saheed, Ahmed Abdalla Ahmed Elkamel, Shamele Battan-Wraith et autres

Background: While recent trials suggest sublobar resection is non-inferior to lobectomy for stage IA non-small cell lung cancer (NSCLC), patients with squamous cell carcinoma (SCC) were underrepresented. We aimed to evaluate outcomes of sublobar resection versus lobectomy in early-stage SCC. Methods: Using …

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The 2025 American Association for Thoracic Surgery (AATS) expert consensus document: Surgical management of esophageal and gastroesophageal junction cancer

Daniela Molena, S.B. Maron, W. Hofstetter, Stephanie Worrell et autres

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Evidence of thymic reconstitution after highly active antiretroviral therapy in HIV‐1 infection

Gareth A. D. Hardy, Stephanie Worrell, Peter Hayes, C. Barnett et autres

OBJECTIVES: We aimed to provide evidence of thymic reconstitution after highly active antiretroviral therapy (HAART) in HIV-1 infected patients and to correlate this with the restoration of peripheral naïve T cells. METHODS: Positron emission tomography (PET) enables definitive evidence of thymic activity, …

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Molecular correlates in AIDS patients following antiretroviral therapy: diversified T‐cell receptor repertoires and in vivo control of cytomegalovirus replication

Stephanie Worrell, Jane R Deayton, Peter Hayes, Vincent C. Emery et autres

OBJECTIVES: To evaluate whether successful, long-term immune reconstitution in vivo can be achieved in end-stage AIDS patients following antiretroviral therapy (ART). METHODS: A 1-year prospective study of changes of CD4+ and CD8+ T-cell surface phenotypes, T-cell receptor (TCR) repertoires and capacity to …

021 Assessment of thymic activity by positron emission tomography in HIV patients on HAART

Stephanie Worrell, Gareth A. D. Hardy, Peter Hayes, R Aspinal et autres

Objective: The source of the increased number of peripheral CD4 cells seen following HAART is still unclear. The possibility of thymically derived T cell clones is exciting since broader T cell repertoires may be achieved. In this pilot study, we followed thymic …

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Cytomegalovirus retinitis after the initiation of highly active antiretroviral therapy: a 2 year prospective study

Suzanne M. Mitchell, W. L Membrey, Michael Youle, A. Obi et autres

BACKGROUND/AIMS: There have been several recent reports suggesting that the natural history of cytomegalovirus retinitis (CMVR) has been significantly modified with the development of highly active antiretroviral therapy (HAART). This 2 year prospective cohort study assesses the effect of HAART on the …

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