Abstract 6999: GDF-15 inhibition overcomes treatment resistance to platinum- and taxane-based cytotoxic chemoimmunotherapy
Neha Vashist, Amelie Köhler, Daniel Schätzlein, Sabrina Genßler et autres
0 citationsCancer Research
Sabrina Genßler
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22Publications signalées
772Citations signalées
1Affiliations récentes
Institutions déclarées
Domaines associés
GDF15 and Related BiomarkersCAR-T cell therapy researchCancer Immunotherapy and BiomarkersImmune Cell Function and InteractionMacrophage Migration Inhibitory Factor
Publications récentes
Abstract 4777: GDF-15 neutralization enhances the therapeutic activity of antibody-drug conjugates
Neha Vashist, Daniel Schätzlein, Sabrina Genßler, José Medina‐Echeverz et autres
1 citationCancer Research
P-02.05 GDF-15 neutralization enhances T cell infiltration in solid tumor models
Arman Öner, David Andreu-Sanz, Pedro Mesquita, Stylianos Michaelides et autres
0 citationsPoster presentations
P-01.16 GDF-15 inhibition overcomes treatment resistance to platinum-based chemoimmunotherapy
N Vashist, Anne Köhler, D Schätzlein, Sabrina Genßler et autres
0 citationsPoster presentations
03.04 Targeted disruption of tumor-borne GDF-15-mediated immunoresistance restores immune checkpoint inhibitor activity in last-line cancer patients
Markus Haake, N Vashist, Katrin Eichler, Matthias Kist et autres
0 citationsOral Presentations
1049 SHP-1 is a central mediator of GDF-15 mediated adhesion inhibition in T-cells
Markus Haake, Neha Vashist, Beatrice Haack, Birgitt Fischer et autres
1 citationRegular and Young Investigator Award Abstracts
1196 GDF-15 neutralizing antibody visugromab increases intratumoral immune cell infiltration to support bispecific T-cell engagers
Sabrina Genßler, Eugen Leo, Markus Haake, Christine Schuberth-Wagner
1 citationRegular and Young Investigator Award Abstracts
12P Immuno-suppressive role of tumour-derived GDF-15 on myeloid cells
Christine Schuberth-Wagner, Isabella-Maria Giese, Manfred Kist, Neha Vashist et autres
1 citationAnnals of Oncology
Tumor-derived GDF-15 blocks LFA-1 dependent T cell recruitment and suppresses responses to anti-PD-1 treatment
Markus Haake, Beatrice Haack, Tina Schäfer, Patrick N. Harter et autres
108 citationsNature Communications
Tumor-derived GDF-15 blocks LFA-1 dependent T cell recruitment and suppresses responses to anti-PD-1 treatment
Markus Haake, Beatrice Haack, Tina Schäfer, Patrick N. Harter et autres
0 citationsFigshare
Abstract 6118: Tumor-derived GDF-15 promotes immune escape of tumors by functional alteration of the myeloid compartment
Markus Haake, Beatrice Haack, Sabrina Genßler, Julia Weigandt et autres
2 citationsCancer Research
568 Tumor-derived GDF-15 prevents therapy success of checkpoint inhibitors by blocking T-lymphocyte recruitment
Markus Haake, Tina Schäfer, Beatrice Haack, Neha Vashist et autres
0 citationsRegular and Young Investigator Award Abstracts
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