Accès ouvert
2026
article
OpenAlex
Marcel Grube, Bianca Ribeiro de Souza, Andrea Neilson, Anna Tinker et autres
OBJECTIVE: Endometrioid ovarian carcinoma (ENOC) is increasingly recognized as a distinct disease entity, yet treatment still largely parallels high-grade serous disease management. We aimed to assemble a large, well-annotated ENOC cohort allowing us to study real-world treatment patterns with special interest on …
ca, de, nl, at, gb, in, se
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Accès ouvert
2026
article
OpenAlex
Marlene Hager, Johannes Ott, Gerda Hofstetter, Iris Holzer et autres
Chronic endometritis is linked to recurrent pregnancy loss and in vitro fertilization failure. The responsiveness to antibiotics suggests a bacterial cause, however endometriosis could also play a role. This study aimed to compare treatment responses to antibiotics of patients with and without …
at, us
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Accès ouvert
2025
article
OpenAlex
Christina T. Grech, Stefanie Aust, Gerda Hofstetter, Esther Uhl et autres
The scavenger receptor CD36 has gained increasing interest in cancer research, with various functions in cell metabolism, angiogenesis, and immune response. This study aimed to investigate the molecular role of CD36 expression on tumor vasculature of advanced high-grade serous ovarian cancer (HGSOC) …
at
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2025
conference-abstract
OpenAlex
Christina Victoria Isabella Tauber, Fabian Trillsch, Magdalena Postl, Valentina Glueck et autres
5574 Background: Prediction of relapse following firstline treatment in patients (pts) with high-grade serous ovarian cancer (HGSOC) remains a major challenge despite recent advances. Reliable markers for assessment of recurrence risk are urgently needed to tailor treatment strategies with circulating tumor DNA …
de, at
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Accès ouvert
2025
article
OpenAlex
Lorenz Kuessel, Lejla Sandrieser, Gerda Hofstetter, Florian Heinzl et autres
Following the U.S. Food and Drug Administration’s warning against power morcellators due to potential cell dissemination of occult malignancy, there has been a shift away from minimally invasive approaches. This concern also overshadows the well-documented advantages of minimally invasive surgery in benign …
at, cz
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Accès ouvert
2025
article
OpenAlex
Valentina Glueck, Christoph Grimm, Magdalena Postl, Christian Brueffer et autres
Background/Objectives: The surgeon’s subjective intraoperative evaluation is the standard of care to assess postoperative residual disease (RD) in advanced epithelial ovarian cancer (EOC). We investigated the feasibility of ctDNA as an objective marker for postoperative RD. Methods: This prospective study included 27 …
at, de, se
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Accès ouvert
2025
article
OpenAlex
Rafał Watrowski, Eva Schuster, Stephan Polterauer, Toon Van Gorp et autres
Background: Cervical cancer (CC) is the fourth most common cancer diagnosis in women worldwide. Infection with high-risk human papillomavirus (HPV) is a critical but not determinative condition for CC development, as several co-factors modulate the progression of HPV-associated cervical lesions. Interleukin-8 (IL-8) …
de, at, be
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Accès ouvert
2024
article
OpenAlex
Rafał Watrowski, Eva Schuster, Toon Van Gorp, Gerda Hofstetter et autres
Single nucleotide polymorphisms (SNPs) of the IL-16 gene have been reported to influence the risk of several cancers, but their role in ovarian cancer (OC) has not been studied. Using the restriction fragment length polymorphism (PCR-RFLP) method, we examined four IL-16 SNPs: …
de, at, be
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2024
article
OpenAlex
Christina T. Grech, Stefanie Aust, Gerda Hofstetter, Esther Uhl et autres
Einleitung: Der Scavenger-Rezeptor CD36 hat in den letzten Jahren zunehmend an Bedeutung gewonnen, aufgrund verschiedene Funktionen im Zellstoffwechsel, in der Angiogenese und bei der Immunantwort. Ziel dieser Studie war es, die molekulare Rolle der CD36-Expression in intratumoralen Gefäßen von fortgeschrittenem hochgradigem serösem …
at
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2024
conference-abstract
OpenAlex
Valentina Paspalj, Christoph Grimm, Magdalena Postl, Christina Victoria Isabella Tauber et autres
5544 Background: The most important predictor of prognosis in patients with high-grade serous ovarian cancer (HGSOC) is complete tumor resection after primary surgery. The current practice for classifying postoperative residual disease is the subjective assessment by the physician at the end of …
de, at
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2024
article
OpenAlex
Christina Victoria Isabella Tauber, Mirela Liana Gliga, Valentina Paspalj, Magdalena Postl et autres
Einleitung Die makroskopische Komplettresektion bei Primäroperation ist der wichtigste klinisch beeinflussbare Prognosefaktor bei Patientinnen mit high-grade serösem Ovarialkarzinom (HGSOC). Die Klassifizierung des postoperativen Resektionsstatus basiert auf der subjektiven Einschätzung der Operierenden am Ende der Operation. Ein objektiver und möglichst indikativer Marker für …
de, at
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Accès ouvert
2024
article
OpenAlex
Ai Wu Zhu, R. Ullrich, Johannes Pammer, Gerda Hofstetter et autres
Frozen section (IFS) assessment enables intraoperative assessment of resection margins, however, its accuracy is subjected to interobserver variability. This study evaluated factors that affect efficacy of resection margin evaluation using IFS in a cohort of breast cancer patients and its impact on …
at
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