Dekun Kong

Reprogramming Enfumafungin Biosynthesis for High-Titer Production in the Endophytic Fungus Hormonema carpetanum ATCC 74360

Jing Wo, Haipeng Yu, Yige Yang, Hongxi Wu et autres

Abstract Enfumafungin is the essential precursor for the FDA-approved antifungal agent Ibrexafungerp, yet its production is hindered by low yields, restrictive solid-state fermentation, and the genetic intractability of its producer strain, Hormonema carpetanum ATCC 74360. Here, we developed a CRISPR/Cas9-mediated platform that …

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Hydrodynamic characteristics of an oscillating water column caisson array mounted on the stepped bottom

Yang Zhang, Jiayao Cui, Dekun Kong, Xiaotian Dong et autres

This paper presents a semi-analytical solution based on linear potential flow theory for the hydrodynamic performance of an oscillating water column (OWC) caisson array deployed on a stepped seabed, where the array consists of multiple identical OWC units placed side by side …

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Hydrogel-shape memory polymer synergistic effect enabled 4D-printed ceramic precursors with programmable recovery onset and reversible deformation

Dekun Kong, Zhihui Zhang, Hailong Wu, Xunjin Li et autres

Abstract Ceramic 4D printing, which integrates dynamic deformation with additive manufacturing, demonstrates significant potential in intelligent manufacturing, on-demand shaping of complex structures, and multifunctional device development. Its core advantage lies in endowing materials with environmentally responsive dynamic deformation capabilities. However, current technologies …

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The siderophore-iron transporter BbMirB is required for the fungal pathogen Beauveria bassiana to repress insect immunity and promote proliferation during colonization of hemocoel

Chenhua Zhu, Qi Liu, Yuhan Chen, Fangfang Tian et autres

ABSTRACT Nutritional immunity plays a vital role in limiting the proliferation of microbial pathogens in vertebrates and invertebrates. During coevolution with their hosts, pathogens have developed tactics to counteract the host nutritional immunity by acquiring iron via s iderophore- i ron t …

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Programmable polylactic acid–ceramics 4D printing with shape memory function

Jingwen Wu, Anfu Guo, Hailong Wu, Junpeng Ma et autres

4D printing is an emerging advancement in additive manufacturing that enables responsive materials to undergo shape transformations, achieving dynamic behaviours. However, 4D printing of ceramics remains challenging due to their brittleness and limited deformability. In this study, we synthesise a novel multifunctional …

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Serine Hydrolase-Catalyzed Polyol Lipids are Necessary for Rodlet Layer Formation on the Cell Wall of Entomopathogenic Fungi

Dekun Kong, He Qian, Dongmei Lin, Huaran Zhang et autres

Some key secondary metabolism genes are important for driving the infection process of entomopathogenic fungi; however, their chemical substance basis has not been well investigated. Here, mixtures of polyol lipids are discovered, which are synthesized through iterative chain transfer–esterification–hydrolysis cycles catalyzed by …

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Influences of the stepped bottom topography on the hydrodynamic performance of an oscillating water column caisson array

Yang Zhang, Dekun Kong, Wenjin Zhu, Xiaotian Dong

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Additive manufacturing of bionic layered ceramic-metal composites for enhanced toughness and damage resistance

Hailong Wu, Anfu Guo, Dekun Kong, Xianliang Sheng et autres

Specific combinations of different materials, interfacial geometries, gradations, and layering in crysomallon squamiferum (CS) shells contribute to their excellent damage resistance. The tortoise shell occlusal joints also exhibit a wide range of resistance to damage due to their unique occlusal structure. Herein, …

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Fungus-derived opine enhances plant photosynthesis

Dekun Kong, Li Cui, Xiaozheng Wang, Jing Wo et autres

Under specific conditions, plant-fungal interactions can stimulate endophytic fungi to secrete abundant metabolites that facilitate plant growth and stress tolerance. Kong et al. discovered a special class of opine synthases from fungi that generate tryptopine A, which enhances the expression of photosynthesis-related …

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Preparation of Bouligand biomimetic ceramic composites and the effect of different fiber orientations on mechanical properties

Hailong Wu, Anfu Guo, Dekun Kong, Jingwen Wu et autres

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Effect of silicon carbide content on microstructure, physical and mechanical properties in vat photopolymerization of alumina

Zhengyu Zhao, Hailong Wu, Anfu Guo, Dekun Kong et autres

Abstract Vat photopolymerization (VPP) printing of ceramic parts offers advantages such as low cost, simple operation, and short fabrication cycles. However, drawbacks include low toughness and brittleness in the printed parts. This study explores enhancing the toughness and strength of alumina (Al …

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Hydrodynamic performance of a pile-supported oscillating water column breakwater in front of a partially reflecting seawall

Yang Zhang, Wenjin Zhu, Qing Yang Xu, Dekun Kong et autres

Integrating wave energy devices with breakwaters can offer an innovative and sustainable approach by combining wave power extraction with wave attenuation. The performance of this integrated system in offshore areas is influenced by the unique characteristics of the coastline. In this paper, …

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