Neil Macdonald

Cascading continental-scale floods across Europe in 1342–1343

Andrea Kiss, Alberto Viglione, Mariano Barriendos, Silvia Enzi et autres

Abstract Europe has experienced extreme floods in recent decades. However, even larger floods are possible and must be considered in flood risk management 1,2 . Their characteristics can be clarified by analysing the largest documented historical floods. In Central Europe, the Magdalena …

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Impact on health outcomes and productive work of adding anti-PD-1 agents to treat early-stage cancers in the United Kingdom: a modelling study

Yan Tan, Sameer A. Greenall, Catarina Neves, Neil Macdonald et autres

Background: Anti-PD-1 agents are recommended in adjuvant or perioperative settings in some early-stage cancers. The health and productivity benefits of anti-PD-1 use on a population level, however, are unknown. Methods: A decision model was developed to quantify the health and productivity outcomes …

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How restoring river catchments can minimise drought and flood risks

Neil Entwistle, Neil Macdonald

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Quantifying the economic value of a national hydrometric network for households

K. P. Thakar, Neil Macdonald, Karyn Morrissey

• Current appraisal methods are undervaluing hydrometric networks. • Choice experiments successfully elicit hydrometric data valuations from the public. • Scottish households positively value river gauging station data and networks. • Environmental attitudes are important determinants of household preferences. • Full economic …

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Unravelling compound risks of hydrological extremes in a changing climate: Typology, methods and futures

Kwok Pan Chun, Thanti Octavianti, Georgia Papacharalampous, Hristos Tyralis et autres

We have witnessed and experienced increasing compound extreme events resulting from simultaneous or sequential occurrence of multiple events in a changing climate. In addition to a growing demand for a clearer explanation of compound risks from a hydrological perspective, there has been …

Reassessing and Extending the Composite Rainfall Record of Manchester, Northwest England: 1786–Present

Neil Macdonald, Robert S. Dietz

A monthly composite rainfall record for the period 1786–present representative of Manchester, northwest England is presented. The 235-year record ranks as the second-longest instrumental rainfall record available for northern England, and the fifth-longest for the UK, and contributes to a growing network …

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Towards a Step Change in Co-Production for Climate Resilience

Nicola Golding, Jenna Ashton, Kate Brown, Steven Chan et autres

Abstract Co-production brought clear benefits to a range of projects across the UK Climate Resilience Programme (UKCR). Experiences were deeply context specific; dependent on those involved, their motivations and expectations. A range of barriers currently exist to achieving the benefits of co-production …

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Putting Climate Resilience in Its Place: Developing Spatially Literate Climate Adaptation Initiatives

Freya Garry, Paul O’Hare, Claire Scannell, Jenna Ashton et autres

Abstract Understanding the socioeconomic, cultural, historical and political nuances of a place is essential for realising effective local decision-making for climate action. People are central to understanding place-based risk and resilience, with consideration of inequalityand vulnerability required for effective place-basedclimate adaptation. Temporality …

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Learning from Arts and Humanities Approaches to Building Climate Resilience in the UK

Edward Brookes, Briony McDonagh, Corinna Wagner, Jenna Ashton et autres

Abstract This chapter shares insights from five arts and humanities-led UK Climate Resilience Programme (UKCR) projects, presenting key learnings and pathways for future research and policy interventions. We highlight the significant potential of place-based arts and humanities approaches for working with and …

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Early prehabilitation in suspected locally advanced and metastatic lung cancer

I. Phillips, Rebecca Petrie, Lindsey Allan, Peter S Hall et autres

OBJECTIVES: The most common treatment for locally advanced and metastatic lung cancer is best supportive care. Patients with lung cancer are often comorbid with a high symptom burden. We wanted to assess whether early prehabilitation was feasible in patients with likely lung …

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Trends in coagulase-negative staphylococci (CoNS), England, 2010–2021

Karthik Paranthaman, Allegra Wilson, Neville Q. Verlander, Graeme Rooney et autres

Objective: To review the epidemiology of coagulase-negative staphylococci (CoNS) in England over the recent 12 year period. Methods: Laboratory-confirmed CoNS reported from sterile sites in patients in England to the UK Health Security Agency (UKHSA) between 2010 and 2021 were extracted from …

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3 The Evolutionary Relationship of Oncology and Palliative Care: A Personal Journey

Neil Macdonald