Marcus Ruhlmann

Correlation of brain injury biomarkers with brain dysfunction, brain injury, and outcomes in critically ill patients: a post hoc exploratory analysis

Marcus Ruhlmann, Lihua Xu, M. Bauer, T. Lehmann et autres

PURPOSE: Clinical assessment of brain dysfunction in critically ill patients is frequently limited by impaired consciousness and poor compliance. Blood-based biomarkers may facilitate detection of neurocognitive impairment, quantify structural brain injury, and improve prognostication. This study evaluated the potential diagnostic role of …

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Fatal Triad of Subarachnoid Hemorrhage, Cervical Hematoma, and Upper Airway Obstruction in a Patient With Neurofibromatosis Type 1: A Case Report

Marcus Ruhlmann, Matthias Gawlitza, Nazife Dinc, Christian Senft et autres

BACKGROUND: Neurofibromatosis type 1 (NF1) is an autosomal dominant genetic disorder, characterized by neurocutaneous lesions. NF1 has a high degree of clinical variability, which can include multiple neoplasia as well as cutaneous, vascular, osseous, and cognitive features. When vascular involvement occurs, NF1 …

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PET in Head and Neck Cancer

Marcus Ruhlmann, Verena Ruhlmann

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Pretherapeutic 124I dosimetry reliably predicts intratherapeutic blood kinetics of 131I in patients with differentiated thyroid carcinoma receiving high therapeutic activities

Marcus Ruhlmann, Wilfried Sonnenschein, James Nagarajah, Ina Binse et autres

AIM: The aim of this study was to assess the agreement between predicted blood uptake values using I and actually measured I blood uptake values (reference) in patients with differentiated thyroid carcinoma receiving largely high therapeutic activities. PATIENTS AND METHODS: Fourteen patients …

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18 F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography May Exclude Malignancy in Sonographically Suspicious and Scintigraphically Hypofunctional Thyroid Nodules and Reduce Unnecessary Thyroid Surgeries

Marcus Ruhlmann, J. Ruhlmann, Rainer Görges, Ken Herrmann et autres

BACKGROUND: F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) is useful in the further characterization of sonographically suspicious and scintigraphically hypofunctional thyroid nodules. METHODS: Sixty-five patients with sonographically suspicious thyroid nodules that were hypofunctional on 99m-Tc-pertechnetate scintigraphy (diameter >1 cm) were retrospectively analyzed. All …

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Hybrid imaging for detection of carcinoma of unknown primary: A preliminary comparison trial of whole-body PET/MRI versus PET/CT

Verena Ruhlmann, Marcus Ruhlmann, Alexander Bellendorf, Johannes Stefan Grueneisen et autres

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124I PET: Pretherapeutic Staging, Detection of Recurrent Thyroid Cancer and Dosimetry

Marcus Ruhlmann, Verena Ruhlmann, Walter Jentzen, Andreas Bockisch

Radioiodine therapy (RIT) is an integral component in the treatment of differentiated thyroid cancer (DTC). Patients usually undergo RIT as initial therapy or later in the case of recurrent or persistent disease. The most important requirement for a successful RIT is the …

High Level of Agreement Between Pretherapeutic 124I PET and Intratherapeutic 131I Imaging in Detecting Iodine-Positive Thyroid Cancer Metastases

Marcus Ruhlmann, Walter Jentzen, Verena Ruhlmann, Cinzia Pettinato et autres

UNLABELLED: The aim of this retrospective study was to assess the level of agreement between PET and scintigraphy using diagnostic amounts of (124)I and therapeutic amounts of (131)I, respectively, in detecting iodine-positive metastases in patients with differentiated thyroid carcinoma. METHODS: The study …

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68Ga-DOTATOC PET/CT in Patients with Iodine- and 18F-FDG–Negative Differentiated Thyroid Carcinoma and Elevated Serum Thyroglobulin

Ina Binse, Thorsten Dirk Poeppel, Marcus Ruhlmann, Samer Ezziddin et autres

This study evaluated the impact of 68Ga-DOTATOC PET/CT in detecting recurrence or metastases in differentiated thyroid carcinoma (DTC) patients with elevated serum thyroglobulin and both negative radioiodine imaging and negative 18F-FDG PET/CT. Methods:68Ga-DOTATOC PET/CT (CT without contrast, low-dose) was performed on average …

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Erratum to: 18F-FDG PET/MRI evaluation of retroperitoneal fibrosis: a simultaneous multiparametric approach for diagnosing active disease

Verena Ruhlmann, Thorsten Dirk Poeppel, Alexander Sascha Brandt, Johannes Stefan Grueneisen et autres

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18F-FDG PET/MRI evaluation of retroperitoneal fibrosis: a simultaneous multiparametric approach for diagnosing active disease

Verena Ruhlmann, Thorsten Dirk Poeppel, Alexander Sascha Brandt, J Grüneisen et autres

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Initial [18F]FDG PET/CT in high-risk DTC patients

Ina Binse, Andreas Bockisch, Sandra Julia Rosenbaum-Krumme, Marcus Ruhlmann

UNLABELLED: In a previous paper, we published the impact of initial [18F]FDG PET/CT (FDG-PET/CT) in high-risk patients with differentiated thyroid cancer (DTC) and described the changes in therapy management. The aim of the present study was to evaluate the prognostic impact of …

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