Accès ouvert
2026
article
OpenAlex
Saliha Selin Özuygur Ermiş, Carina Malmhäll, Magnus P. Borres, Robert Movérare et autres
ABSTRACT Background As a surrogate for eosinophilic activation, eosinophil‐derived neurotoxin (EDN) is a potential clinical biomarker. However, EDN levels and discriminatory ability in different asthma phenotypes are unknown. We quantified serum and nasal lavage fluid (NLF) EDN levels and assessed the potential …
se, fi
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Accès ouvert
2026
article
OpenAlex
Rickard Zeijlon, Sara Zooq, Angela Poller, Lowie Vanfleteren et autres
INTRODUCTION: Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) may cause stress-induced transient acute cardiac dysfunction through myocardial stunning, in the form of exacerbation-triggered Takotsubo syndrome (referred to as Takotsubo stunning). Although prior studies suggest an association between AECOPD and transient cardiac …
se, be, no
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Accès ouvert
2025
conference-abstract
OpenAlex
Roxana K. Mincheva, Polina A. Petrova, Steliyana Valeva, Katya Mollova et autres
Guillain-Barré syndrome (GBS) is an acute inflammatory autoimmune polyneuropathy that leads to sudden and progressive muscle weakness, often starting in the lower limbs and involving the respiratory musculature. It is the leading cause of acute flaccid paralysis in developed countries. The main …
bg
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Accès ouvert
2025
article
OpenAlex
Muwada Bashir Awad Bashir, Daniil Lisik, Saliha Selin Özuygur Ermiş, Rani Basna et autres
Non peer reviewed
se, fi
(code pays fourni par la source)
2025
conference-abstract
OpenAlex
Radhika Jadhav, Selin Ercan, Reshed Abohalaka, Pinja Ilmarinen et autres
Background: Obesity is associated with worsening of asthma, but the role of fat mass percentage (FATP) in asthma remains less understood. Aims: To examine the association between FATP and asthma outcomes in an adult-representative sample. Methods: Body FATP was obtained from participants …
se, fi
(code pays fourni par la source)
2025
conference-abstract
OpenAlex
Daniil Lisik, Helena Bäckman, Rani Basna, Linnéa Hedman et autres
Background: Asthma phenotypes are heterogeneous and dependent on age, but little is known about adult-onset asthma phenotypes across ages of onset. Aims and Objectives: To identify and characterize adult-onset astma phenotypes by different ages of onset. Methods: Clinical and survey data from …
se, fi
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Accès ouvert
2025
article
OpenAlex
Daniil Lisik, Helena Bäckman, Rani Basna, Linnéa Hedman et autres
Non peer reviewed
se, fi
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Saliha Selin Özuygur Ermiş, Carina Malmhäll, Magnus P. Borres, Robert Movérare et autres
Background: Eosinophil-derived neurotoxin (EDN), an eosinophil granule protein, is a candidate biomarker in asthma to reflect eosinophilic activation. Objective: We sought to characterize the distribution of serum and nasal lavage fluid (NLF) EDN levels in different adult population subgroups and assess the …
se, fi
(code pays fourni par la source)
Accès ouvert
2025
preprint
OpenAlex
Daniil Lisik, Helena Bäckman, Rani Basna, Linnéa Hedman et autres
Background: Asthma is a heterogeneous disease of phenotypes that differ by age at onset. At the same time, there is no consensus on the correct cut-off to determine late-onset asthma. This study aimed to characterize phenotypes of late-onset asthma in the general …
se
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Accès ouvert
2025
article
OpenAlex
Carina Malmhäll, Jenny Calvén, Julie Weidner, Kristina Johansson et autres
BACKGROUND: Sex differences have been reported in the incidence, prevalence and severity of asthma. Previous findings from animal models have revealed sex-related differences in inflammatory pathways that may contribute to asthma pathogenesis, but human studies are limited. METHODS: Airway and blood samples …
se, fi, us
(code pays fourni par la source)
2024
conference-abstract
OpenAlex
Carina Malmhäll, Jenny Calvén, Julie Weidner, Kristina Johansson et autres
Background: There are notable sex differences in the incidence, prevalence, and severity of asthma. Let-7 miRNAs were found to be decreased in asthma, but a possible role of Let-7 miRNAs in sex disparity in asthma is unknown. The Let-7 family was shown …
se, fi
(code pays fourni par la source)
2024
conference-abstract
OpenAlex
Muwada Bashir Awad Bashir, Daniil Lisik, Saliha Selin Özuygur Ermiş, Rani Basna et autres
Background: Asthma is a heterogeneous airway disease characterized by numerous phenotypes. Identification of clinically meaningful phenotypes, using advanced machined based methods and large population-based sample is paramount for optimizing asthma management. Objectives: To use a novel machine learning approach to determine asthma …
se, fi
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