Mathieu Nonnenmacher

Highly conserved brain vascular receptor ALPL mediates transport of engineered AAV vectors across the blood-brain barrier

Tyler C. Moyer, Brett Hoffman, Weitong Chen, Ishan Shah et autres

us (code pays fourni par la source)

Highly conserved brain vascular receptor ALPL mediates transport of engineered viral vectors across the blood-brain barrier

Tyler C. Moyer, Brett Hoffman, Weitong Chen, Ishan Shah et autres

us (code pays fourni par la source)

SYST-13 AAV VECTOR ENCODING FC MODIFIED HER2 ANTIBODIES REDUCES TUMOR BURDEN WITH MINIMIZED PERIPHERAL EXPOSURE IN MODELS OF BREAST CANCER BRAIN METASTASIS

Dan R. Laks, Xiao‐Qin Ren, Ishan Shah, Jeffrey S. Thompson et autres

us (code pays fourni par la source)

Assessing recent milestones in AAV capsid discovery & development for CNS applications

Mathieu Nonnenmacher

Every little bit helps: A single-residue switch in a vascular AAV enables blood-brain barrier penetration

Dirk Grimm, Mathieu Nonnenmacher

de, us (code pays fourni par la source)

Gene editing reverses arrhythmia susceptibility in humanized PLN-R14del mice: modelling a European cardiomyopathy with global impact

Jaydev Dave, Nour Raad, Nishka Mittal, Lu Zhang et autres

us, gb, kr (code pays fourni par la source)

Rapid evolution of blood-brain-barrier-penetrating AAV capsids by RNA-driven biopanning

Mathieu Nonnenmacher, Wei Wang, Matthew A. Child, Xiao‐Qin Ren et autres

us (code pays fourni par la source)

Functional and transcriptomic insights into pathogenesis of R9C phospholamban mutation using human induced pluripotent stem cell-derived cardiomyocytes

Delaine K. Ceholski, Irene C. Turnbull, Chi‐Wing Kong, Simon Koplev et autres

us, hk, se (code pays fourni par la source)

Abstract 185: Genome Editing of Isogenic Human Induced Pluripotent Stem Cells Allows for Functional and Transcriptomic Insights Into Hereditary Dilated Cardiomyopathy Caused by Phospholamban Mutations

Delaine K. Ceholski, Irene C. Turnbull, Simon Koplev, Chi‐Wing Kong et autres

us, pl, gr, se, it (code pays fourni par la source)

Genomic correction of familial cardiomyopathy in human engineered cardiac tissues

Francesca Stillitano, Irene C. Turnbull, Ioannis Karakikes, Mathieu Nonnenmacher et autres

us, fr (code pays fourni par la source)

Moderated Poster session - Genetic, Epigenetic & Integrative480Inhibiting mitochondrial fission with Mdivi-1 directs cardiac differentiation of human induced pluripotent stem cells via protein kinase CK2481A novel role of tristetraprolin in preventing mitochondrial dysfunction in the heart against iron deficiency by optimizing expression of Rieske iron-sulfur protein482Different therapeutic approaches to downregulate the activation of the hepatic interleukin-6/stat3/complement pathway in two models of autoimmune myocarditis483In vitro and in vivo genome engineering of Dilated Cardiomyopathy caused by phospholamban R14 deletion.484Contractile dysfunction of induced pluripotent stem cell-derived cardiomyocytes from a duchenne muscular dystrophy patient485Cigarette smoking increases expression of the G protein-coupled receptor 15 mRNA by change in CpG methylation486Cardiogenic potential of iPSC from cardiac progenitor cells

S Lim, T Sato, Fernanda Marino, F Stillitano et autres

Cardiac Stim1 Silencing Impairs Adaptive Hypertrophy and Promotes Heart Failure Through Inactivation of mTORC2/Akt Signaling

Ludovic Bénard, Jae Gyun Oh, Marine Cacheux, Ah Young Lee et autres

fr (code pays fourni par la source)