Muzny Dm

cellSTAAR: incorporating single-cell-sequencing-based functional data to boost power in rare variant association testing of noncoding regions

Eric Van Buren, Yi Zhang, Xihao Li, Margaret Sunitha Selvaraj et autres

us, cn, tw, it, dk, as, ws, ca, br (code pays fourni par la source)

Challenges of Francisella classification exemplified by an atypical clinical isolate

Lisa M. Matz, KY Kamdar, M. E. Holder, GA Metcalf et autres

us (code pays fourni par la source)

An integrated map of structural variation in 2,504 human genomes_supplement

Sudmant Ph, Tobias Rausch, Gardner Ej, Handsaker Re et autres

The common marmoset genome provides insight into primate biology and evolution

Kim C Worley, Jeffrey Rogers, Muzny Dm, George M. Weinstock et autres

We report the whole-genome sequence of the common marmoset (Callithrix jacchus). The 2.26-Gb genome of a female marmoset was assembled using Sanger read data (6×) and a whole-genome shotgun strategy. A first analysis has permitted comparison with the genomes of apes and …

us, it, sg, sk, ch, de, gb, es (code pays fourni par la source)

Comprehensive molecular characterization of clear cell renal cell carcinoma

Chad J. Creighton, Margaret Morgan, Preethi H. Gunaratne, David A. Wheeler et autres

Genetic changes underlying clear cell renal cell carcinoma (ccRCC) include alterations in genes controlling cellular oxygen sensing (for example, VHL) and the maintenance of chromatin states (for example, PBRM1). We surveyed more than 400 tumours using different genomic platforms and identified 19 …

us, ca (code pays fourni par la source)

Whole-genome sequence–based analysis of high-density lipoprotein cholesterol

Alanna C. Morrison, Xiaoming Liu, Alexander Li, Eric Boerwinkle et autres

us (code pays fourni par la source)

Combined sequence-based and genetic mapping analysis of complex traits in outbred rats

Amelie Baud, Regina Lopez-Aumatell, Richard Mott, Jonathan Flint et autres

gb, es, fr, nl, se, us, de (code pays fourni par la source)

An integrated map of genetic variation from 1,092 human genomes

Gil A. McVean, Peter Donnelly, Anjali Gupta-Hinch, Zamin Iqbal et autres

By characterizing the geographic and functional spectrum of human genetic variation, the 1000 Genomes Project aims to build a resource to help to understand the genetic contribution to disease. Here we describe the genomes of 1,092 individuals from 14 populations, constructed using …

gb, us, it (code pays fourni par la source)

A map of human genome variation from population-scale sequencing

Richard Durbin, John Burton, David M. Carter, Carol Churcher et autres

The 1000 Genomes Project aims to provide a deep characterization of human genome sequence variation as a foundation for investigating the relationship between genotype and phenotype. Here we present results of the pilot phase of the project, designed to develop and compare …

gb, fi, us (code pays fourni par la source)

The genome of the model beetle and pest Tribolium castaneum

Stephen Richards, Richard A. Gibbs, George M. Weinstock, Richard Gibbs et autres

Tribolium castaneum is a member of the most species-rich eukaryotic order, a powerful model organism for the study of generalized insect development, and an important pest of stored agricultural products. We describe its genome sequence here. This omnivorous beetle has evolved the …

us, de, dk, cn, jp, gb (code pays fourni par la source)

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

Ewan Birney, Paul Flicek, Damian Keefe, Ari Löytynoja et autres

gb, us, es, il, it, sg, ch, at, de (code pays fourni par la source)

DNA homology of Brucella abortus strains 19 and 2308.

Muzny Dm, Ficht Ta, Templeton Jw, Adams Lg

The restriction endonuclease digestion DNA patterns from Brucella abortus strains 19 and 2308 were examined with 11 restriction enzymes (AvaI, BamHI, BglII, BstEII, DdeI, EcoRI, HindIII, KpnI, PstI, XbaI, and SalI). The DNA electrophoretic banding patterns between the 2 strains were highly …

us (code pays fourni par la source)