Elisabeth Bruder

Pathologic findings of the placenta and clinical implications – recommendations for placental examination

Thomas Menter, Elisabeth Bruder, Irène Hösli, Olav Lapaire et autres

The placenta is a unique and complex organ that combines the circulatory systems of two or more individuals within a single dynamic organ with a set, short lifespan. A diverse spectrum of disorders, including infections as well as metabolic, genetic, circulatory, and …

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Bladder Neoplasia in Pediatric Patients—A Single-Center Experience Including a Case Series

Frank-Martin Haecker, Elisabeth Bruder

Objective: Bladder lesions like urothelial carcinoma are rare in the first two decades of life. A biopsy of the bladder or urinary cytological examination is seldom required. Gross painless hematuria is the most relevant clinical syndrome. Methods: A retrospective analysis of surgical …

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Extremely severe hypochloremic metabolic alkalosis after ileorectal anastomosis in a patient with chronic intestinal pseudo-obstruction

Peter Heinz‐Erian, Andreas Janecke, Thomas H Müller, Peter Rehder et autres

Chronic intestinal pseudo-obstruction (CIPO), defined as chronic constipation without mechanical obstruction of the gastrointestinal tract [1, 2], often presents with a truly chameleon-like symptomatology including irregular defecation, abdominal pain and distension, nausea, vomiting, and sometimes fluid/electrolyte imbalance. Although diarrhea was found in …

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A Case Study of Zoonotic Chlamydia abortus Infection: Diagnostic Challenges From Clinical and Microbiological Perspectives

Anne-Valérie Burgener-Gasser, Helena M. B. Seth-Smith, Sina Kern-Baumann, Ana Durovic et autres

Abstract Chlamydia abortus is the most common causative agent of abortion in small ruminants, but it is poorly recognized as a human pathogen. In most published case studies, diagnosis remained difficult and often resulted in delayed initiation of therapy. In this case …

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Classification of placental disorders according to the FIGO criteria. A case series at the University Hospital of Basel

LF Gueneux, Irène Hösli, Thomas Menter, Elisabeth Bruder et autres

Objective The incidence and prevalence of PAS (Placenta Accreta Spectrum) are increasing and demand a systematic, uniform classification that allows national and international comparisons. The pathologic diagnosis terms of placenta accreta, increta and percreta cannot be accurately classified prenatally. There is need …

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Associations of Mucosal Nerve Fiber Innervation Density with Hirschsprung-Associated Enterocolitis: A Retrospective Three-Center Cohort Study

Michèle Moesch, Jakob Usemann, Elisabeth Bruder, Philipp Romero et autres

Abstract Objective Hirschsprung's disease (HSCR) is a congenital intestinal neurodevelopmental disorder characterized by the absence of enteric ganglion cells in the distal colon. Although Hirschsprung-associated enterocolitis (HAEC) is the most frequent life-threatening complication in HSCR, to date reliable biomarkers predicting the likelihood …

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Perfusion-Based Bioreactor Culture and Isothermal Microcalorimetry for Preclinical Drug Testing with the Carbonic Anhydrase Inhibitor SLC-0111 in Patient-Derived Neuroblastoma

Zihe Huo, Remo Bilang, Claudiu Trandafir Supuran, Nicolas von der Weid et autres

Neuroblastoma is a rare disease. Rare are also the possibilities to test new therapeutic options for neuroblastoma in clinical trials. Despite the constant need to improve therapy and outcomes for patients with advanced neuroblastoma, clinical trials currently only allow for testing few …

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Congenital orbital teratoma: A clinicopathologic case report

Aja Reinhold, Peter Meyer, Elisabeth Bruder, Jehuda Soleman et autres

PURPOSE: Orbital teratoma can be removed in order to preserve the bulb. OBSERVATIONS: Case report of a newborn with an orbital tumor. After spontaneous birth, a massive bulbus protrusion on the left side was observed. Magnetic Resonance Imaging (MRI) diagnosis showed an …

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Histologic Aspect of the Curved Vomerine Mucosa in Cleft Lip and Palate

Benito K. Benitez, Andrzej Brudnicki, Prasad Nalabothu, Jeannette A. von Jackowski et autres

BACKGROUND: Common surgical techniques aim to turn the entire vomerine mucosa with vomer flaps either to the oral side or to the nasal side. The latter approach is widely performed due to the similarity in color to the nasal mucosa. However, we …

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Infraorbital Subcutaneous Intravascular Lobular Capillary Hemangioma After Rhinoplasty

Benedict Kaiser, Obinna Chijioke, Elisabeth Bruder, Martin Thanh-Long Takes et autres

BACKGROUND: Lobular capillary hemangioma (LCH; also referred to as pyogenic granuloma) is a common benign vascular tumor that is characterized by proliferation of capillaries with a lobular architecture. Lobular capillary hemangioma can involve superficial cutaneous, mucosal, or subcutaneous structures; the subcutaneous and …

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SARS-CoV-2/COVID-19-Auswirkungen auf die Plazenta

Thomas Menter, Alexandar Tzankov, Elisabeth Bruder

From the very beginning, special attention regarding severe acute respiratory syndrome-coronavirus‑2 (SARS-CoV-2) and the resulting coronavirus disease-2019 (COVID-19) has been paid to pregnant women.In this review, after a short introduction into the immunodefensive role of the placenta and viral infections in general, …

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Lack of Mucosal Cholinergic Innervation Is Associated With Increased Risk of Enterocolitis in Hirschsprung's Disease

Simone Keck, Virginie Galati‐Fournier, Urs Kym, Michèle Moesch et autres

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