Colton Wright

Automated Classification of At-home SARS-CoV-2 Lateral Flow Assay Test Results Using Image Matching and Transfer Learning: Multiple-Pipeline Study

Meysam Safarzadeh, Carly Herbert, Steven Koon Wong, Pamela Stamegna et autres

Abstract Introduction Rapid antigen testing for SARS-CoV-2 is an important tool for the timely diagnosis of COVID-19, especially in at-home settings. However, the interpretation of test results can be subjective and prone to error. We describe an automated image analysis pipeline to …

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Artificial intelligence conversational agents in mental health: Patients see potential, but prefer humans in the loop

Hye Sun Lee, Colton Wright, Julia Ferranto, Jessica Buttimer et autres

Background: Digital mental health interventions, such as artificial intelligence (AI) conversational agents, hold promise for improving access to care by innovating therapy and supporting delivery. However, little research exists on patient perspectives regarding AI conversational agents, which is crucial for their successful …

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Relationship Between Acute SARS-CoV-2 Viral Clearance and Long COVID-19 (Long COVID) Symptoms: A Cohort Study

Carly Herbert, Annukka A.R. Antar, John Broach, Colton Wright et autres

BACKGROUND: The relationship between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral dynamics during acute infection and the development of long coronavirus disease 2019 (COVID-19), or "long COVID," is largely unknown. METHODS: Between October 2021 and February 2022, 7361 people not known …

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Design, creation, and use of the Test Us Bank (TUB) COVID-19 sample biorepository

John Broach, Chad J. Achenbach, S. Behar, Laurel O’Connor et autres

Shortly after the first case of SARS-CoV-2 was diagnosed a public health emergency (PHE) was declared and a multi-agency response was initiated within the US federal government to create and propagate testing capacity. As part of this response, an unprecedented program designated …

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Relationship between acute SARS-CoV-2 viral clearance with Long COVID Symptoms: a cohort study

Carly Herbert, Annukka A.R. Antar, John Broach, Colton Wright et autres

Introduction: The relationship between SARS-CoV-2 viral dynamics during acute infection and the development of long COVID is largely unknown. Methods: A total of 7361 asymptomatic community-dwelling people enrolled in the Test Us at Home parent study between October 2021 and February 2022. …

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Performance of and Severe Acute Respiratory Syndrome Coronavirus 2 Diagnostics Based on Symptom Onset and Close Contact Exposure: An Analysis From the Test Us at Home Prospective Cohort Study

Carly Herbert, Biqi Wang, Honghuang Lin, Yan Yi et autres

Background: Understanding changes in diagnostic performance after symptom onset and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure within different populations is crucial to guide the use of diagnostics for SARS-CoV-2. Methods: The Test Us at Home study was a longitudinal cohort …

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Patient perspectives of artificial intelligence chatbots in mental healthcare: A qualitative study

Sarah Lee, Colton Wright, Julia Ferranto, Jessica Buttimer et autres

This qualitative study enrolled individuals with self-reported diagnoses of mild to moderate anxiety and conducted semi-structured interviews to explore patient experiences, perceptions, and acceptability of AI chatbots in mental healthcare. (PsycExtra Database Record (c) 2026 APA, all rights reserved)

Design, Creation, and Use of The Test Us Bank (TUB) COVID-19 Sample Biorepository

John Broach, Chad J. Achenbach, S. Behar, Laurel O’Connor et autres

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Performance of Rapid Antigen Tests to Detect Symptomatic and Asymptomatic SARS-CoV-2 Infection

Apurv Soni, Carly Herbert, Honghuang Lin, Yan Yi et autres

BACKGROUND: The performance of rapid antigen tests (Ag-RDTs) for screening asymptomatic and symptomatic persons for SARS-CoV-2 is not well established. OBJECTIVE: To evaluate the performance of Ag-RDTs for detection of SARS-CoV-2 among symptomatic and asymptomatic participants. DESIGN: This prospective cohort study enrolled …

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Performance of Rapid Antigen Tests Based on Symptom Onset and Close Contact Exposure: A secondary analysis from the Test Us At Home prospective cohort study

Carly Herbert, Biqi Wang, Honghuang Lin, Nathaniel Hafer et autres

Background: The performance of rapid antigen tests for SARS-CoV-2 (Ag-RDT) in temporal relation to symptom onset or exposure is unknown, as is the impact of vaccination on this relationship. Objective: To evaluate the performance of Ag-RDT compared with RT-PCR based on day …

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Comparison of Rapid Antigen Tests' Performance Between Delta and Omicron Variants of SARS-CoV-2

Apurv Soni, Carly Herbert, Andreas Filippaios, John Broach et autres

BACKGROUND: It is important to document the performance of rapid antigen tests (Ag-RDTs) in detecting SARS-CoV-2 variants. OBJECTIVE: To compare the performance of Ag-RDTs in detecting the Delta (B.1.617.2) and Omicron (B.1.1.529) variants of SARS-CoV-2. DESIGN: Secondary analysis of a prospective cohort …

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Performance of Rapid Antigen Tests to Detect Symptomatic and Asymptomatic SARS-CoV-2 Infection

Apurv Soni, Carly Herbert, Honghuang Lin, Yan Yi et autres

Background: Performance of rapid antigen tests for SARS-CoV-2 (Ag-RDT) varies over the course of an infection, and their performance in screening for SARS-CoV-2 is not well established. We aimed to evaluate performance of Ag-RDT for detection of SARS-CoV-2 for symptomatic and asymptomatic …

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