Accès ouvert
2026
article
OpenAlex
Lu Liu, Jing-wen Zhang, Yi Fu, J Chen et autres
Introduction: HER2 (ERBB2) alterations are recognized oncogenic drivers in non-small cell lung cancer, but they are uncommon and poorly characterized in lung squamous cell carcinoma (LSCC). Case Presentation: We report a patient with initially resected stage IA2 LSCC who subsequently developed metastatic …
cn, tw, us
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Accès ouvert
2026
article
OpenAlex
Ziming Liu, M W Li, Chuanjiang Yang, C H I Zhang et autres
Introduction: Chinese expatriate oilfield employees working in Iraq are exposed to multiple occupational and psychosocial stressors, yet evidence on sleep disturbance and its correlates in this workforce remains limited. Methods: A cross-sectional survey was conducted among 917 employees. 826 (90.1%) were included …
cn
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Accès ouvert
2026
article
OpenAlex
C S, Jie Chen, Yi Fu, Lou Liu et autres
BACKGROUND: Competence in radiation oncology is still commonly expected to emerge through apprenticeship, although essential tasks such as target delineation, treatment-plan review, and multidisciplinary reasoning are not reliably sampled by end-of-rotation examinations alone. METHODS: We conducted a single-center prospective educational intervention at …
cn
(code pays fourni par la source)
2026
conference-abstract
OpenAlex
Huijuan Yang, Wei Jiang, Yi Fu, Lina Yin et autres
5559 Background: Initial results from our trial showed the anti-tumor activity and good tolerance of CDK4/6 inhibitor dalpiciclib combined with NSAIs in patients (pts) with ER+ R/M ovarian cancer and uterine neoplasms (SGO, 2024, #S283; IGCS, 2025, #397). Here, we report updated …
cn
(code pays fourni par la source)
2026
conference-abstract
OpenAlex
Huijuan Yang, Yi Fu, Shuai Liu, Yi-Xiang Wang et autres
5586 Background: Ovarian clear cell carcinoma (OCCC) is a histologically aggressive subtype of epithelial ovarian cancer with limited effective treatment options, particularly for recurrent disease. This study aims to evaluate the efficacy and safety of surufatinib (a kinase inhibitor targeting VEGFR 1, …
cn
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Accès ouvert
2026
article
OpenAlex
Qinglin Ke, Han Lin, Yitong Zha, Haitao Zhang et autres
Gene family expansion represents an important evolutionary mechanism driving functional innovation of genes in plants. This study investigated the expansion and evolutionary patterns of the peroxidase (POD) gene family in barley (Hordeum vulgare L.), a global important cereal crop. Our analyses revealed …
cn
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Accès ouvert
2026
article
OpenAlex
Xuyang Wang, Jiageng Tang, Shuyu Zhang, Xu Chen et autres
Lactate, long regarded as the terminal product of glycolysis, is now recognized as a signaling metabolite that shapes diverse physiological and pathological processes. Lysine lactylation, a recently identified post-translational modification (PTM), has emerged as a key regulator of disease onset and progression. …
cn
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Accès ouvert
2025
article
OpenAlex
Siyuan Yu, Pengxiang Ji, Ting Du, Zuohua Liu et autres
Angiopoietin-like 4 (ANGPTL4) expression is increased in wound tissue and contributes to wound healing. However, the underlying mechanisms are not fully understood. Here, we demonstrate that ANGPTL4 expression is significantly increased in epidermal stem cells (EpSCs) in the periwound epidermis during wound …
cn
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Accès ouvert
2025
article
OpenAlex
Chenying Ma, Yi Fu, Lou Liu, Jie Chen et autres
BACKGROUND: This study aimed to develop and validate a multi-temporal magnetic resonance imaging (MRI)-based delta-radiomics model to accurately predict severe acute radiation enteritis risk in patients undergoing total neoadjuvant therapy (TNT) for locally advanced rectal cancer (LARC). METHODS: A retrospective analysis was …
cn
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Accès ouvert
2025
article
OpenAlex
Shan Miao, Lin Lin, Menghong Long, Yi Fu
RRAS2, induced by H3 lysine 18 lactylation (H3K18la), plays a vital role in activating signal transduction pathways that control cell proliferation. However, fewer studies focused on the role of H3K18la-mediated RRAS2 in head and neck squamous cell carcinoma (HNSCC). The RRAS2 expression …
cn
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Accès ouvert
2025
conference-abstract
OpenAlex
Huijuan Yang, Wei Jiang, Xuan Pei, Yi Wang et autres
e17580 Background: Disitamab Vedotin (DV) is a newly developed antibody-drug conjugate targeting human epidermal growth factor 2 (HER2) that is comprised of hertuzumab coupling monomethyl auristatin E(MMAE) via a cleavable linker. It has been approved in HER2-expressing urothelial and gastric cancers. The …
cn
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Accès ouvert
2025
article
OpenAlex
Li Liang, Yi Fu, Di Zhou
Background: Kidney diseases are a prevalent global health concern, and despite ongoing research, there remains a lack of fully effective clinical treatments to prevent or halt their progression. Consequently, it is encouraged to identify novel biomarkers, establish early diagnostic methods, pinpoint key …
us, cn
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