Nicolas Bovy

FEASIBILITY, RELIABILITY AND CLINICAL VALIDITY OF STRIDE VELOCITY AS A REAL-LIFE DIGITAL OUTCOME IN KNEE OSTEOARTHRITIS

Camila Gonzalez Barral, Margaux Poleur, Nicolas Bovy, Georgia Stimpson et autres

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First-in-human, double-blind, randomized phase 1b study of peptide immunotherapy IMCY-0098 in new-onset type 1 diabetes: an exploratory analysis of immune biomarkers

Jean Van Rampelbergh, Peter Achenbach, Richard David Leslie, Martin Kindermans et autres

Abstract Background IMCY-0098, a synthetic peptide developed to halt disease progression via elimination of key immune cells in the autoimmune cascade, has shown a promising safety profile for the treatment of type 1 diabetes (T1D) in a recent phase 1b trial. This …

be, de, gb, fr (code pays fourni par la source)

First-in-human, double-blind, randomized phase 1b study of peptide immunotherapy IMCY-0098 in new-onset type 1 diabetes

Jean Van Rampelbergh, Peter Achenbach, Richard David Leslie, Mohammad Alhadj Ali et autres

BACKGROUND: T cells. Achieving glycemic targets in T1D remains challenging in clinical practice; new treatments aim to halt autoimmunity and prolong β-cell survival. IMCY-0098 is a peptide derived from human proinsulin that contains a thiol-disulfide oxidoreductase motif at the N-terminus and was …

be, de, gb, fr (code pays fourni par la source)

Gene expression signature predicts rate of type 1 diabetes progression

Tomi Suomi, Inna Starskaia, Ubaid Ullah, Omid Rasool et autres

BACKGROUND: Type 1 diabetes is a complex heterogenous autoimmune disease without therapeutic interventions available to prevent or reverse the disease. This study aimed to identify transcriptional changes associated with the disease progression in patients with recent-onset type 1 diabetes. METHODS: Whole-blood samples …

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Immunologic mechanisms of a short-course of Lolium perenne peptide immunotherapy: A randomized, double-blind, placebo-controlled trial

Hanisah Sharif, Iesha Singh, Lubna Kouser, Ralph Mösges et autres

gb, de, be (code pays fourni par la source)

Immunomodulatory properties of lolium perenne peptides for the treatment of seasonal allergic rhinitis

JA Layhadi, Hanisah Sharif, Iesha Singh, Abigail O. Robb et autres

Lolium perenne peptides for treatment of grass pollen allergy: A randomized, double-blind, placebo-controlled clinical trial

Mohamed H. Shamji, Jan Ceuppens, Claus Bachert, Peter William Hellings et autres

Allergen immunotherapy (AIT), first used more than a century ago,1Noon L. Prophylactic inoculation against hayfever.Lancet. 1911; 1: 1572-1573Abstract Scopus (1131) Google Scholar is an effective treatment in patients with seasonal allergic rhinitis. Allergen extract can be administered as subcutaneous or sublingual immunotherapy. …

gb, be (code pays fourni par la source)

Circulating microRNA-based screening tool for breast cancer

Pierre Frères, Stéphane Wenric, Meriem Boukerroucha, Corinne Fasquelle et autres

// Pierre Frères 1, 2, * , Stéphane Wenric 2, * , Meriem Boukerroucha 2 , Corinne Fasquelle 2 , Jérôme Thiry 2 , Nicolas Bovy 3 , Ingrid Struman 3 , Pierre Geurts 4 , Joëlle Collignon 1 , Hélène Schroeder …

be (code pays fourni par la source)

Implication of miRNAs in the communication between endothelial cells and vascular muscle cells

Marie Fontaine, Nicolas Bovy, Ingrid Struman

be (code pays fourni par la source)

Neoadjuvant chemotherapy in breast cancer patients induces miR-34a expression

Pierre Frères, Claire Josse, Nicolas Bovy, Meriem Boukerroucha et autres

be (code pays fourni par la source)

Analyse des propriétés anti-tumorales des exosomes endothéliaux dans le cancer du sein suite au transfert du microARN miR-503

Nicolas Bovy

L’angiogenèse est un processus essentiel au développement tumoral ainsi qu’à la dissémination des métastases. De plus, il a été démontré ces dernières années que les miARN, des ARN non codant d'une vingtaine de nucléotides régulant l’expression des gènes au niveau post-transcriptionnel, jouent …

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Endothelial exosomes contribute to the antitumor response during breast cancer neoadjuvant chemotherapy via microRNA transfer

Nicolas Bovy, Benoît Blomme, Pierre Frères, Stella Dederen et autres

// Nicolas Bovy 1 , Benoît Blomme 1 , Pierre Frères 2 , Stella Dederen 1 , Olivier Nivelles 1 , Michelle Lion 1 , Oriane Carnet 3 , Joseph A. Martial 1 , Agnès Noël 3 , Marc Thiry 4 , …

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