Benjamin Straube

The timeline of brain aging in major depression: A prospective study from before first-onset to established illness

Maximilian Konowski, Anna Kraus, Janik Goltermann, Jan Ernsting et autres

Major depressive disorder (MDD) has been associated with accelerated structural brain aging, yet whether this reflects a pre-existing neurobiological vulnerability, a dynamic acute state effect, or an accumulating biological residual remains unresolved. Across two longitudinal cohorts (N=3220), including a unique sample of …

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Symptom network connectivity in patients with anxiety disorders with and without comorbid depressive disorder

Maximilian Jäger, Stephan Goerigk, Ingmar Heinig, Volker Arolt et autres

BACKGROUND: Comorbidity between anxiety and depression is highly prevalent. Network theory offers a psychometric approach to studying psychopathology and comorbidity. This study investigated connectivity between anxiety and depressive symptoms in a transdiagnostic, outpatient anxiety sample using network analysis. METHOD: In a secondary …

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Secure Attachment despite Childhood Maltreatment: Behavioral and Neural Correlates of Interpersonal Resilience

Katharina Brosch, Vincent Hammes, Paula Usemann, Frederike Stein et autres

Abstract Background Childhood maltreatment is a traumatic interpersonal stressor that increases vulnerability for depression in adulthood. However, some individuals show secure attachment despite childhood maltreatment, a pattern that can be described as interpersonal resilience. The present study examined the behavioral and neural …

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How do expectations shape actions?

Benjamin Straube

Utilization of different types of safety behavior during exposure-based CBT for anxiety disorders and its correlates

Caroline im Brahm, Ingmar Heinig, Stephan Goerigk, Volker Arolt et autres

Safety behavior is used to prevent or minimize perceived threats and contributes to the maintenance of anxiety disorders. Various types of safety behavior (e.g. cognitive, interoceptive strategies, aids, substances) are prevalent. Although assumed to be counterproductive during exposure-based CBT, little is known …

Brain Ageing in Social Anxiety Disorder: An ENIGMA-Anxiety Mega-Analysis Across 26 International Cohorts

Kimberly V. Blake, Jonathan Ipser, Alyssa R. Amod, Tobias Kaufmann et autres

Abstract Social anxiety disorder (SAD) is among the most prevalent anxiety disorders, and it has been associated with signs of advanced biological ageing. Despite this, brain age research on anxiety disorders remains limited. This mega-analysis investigated brain ageing in adults with SAD …

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The role of attention in perceptual biases in patients with schizophrenia spectrum disorder and healthy controls

Alexander C. Schütz, Ogün Bolat, Kin Kori, Tilo Kircher et autres

Ambiguous or uncertain sensory information is often resolved by incorporating prior assumptions about the most likely interpretation. Similar neural structures and a common visual environment typically lead to homogeneous priors in the population. Ambiguous motion displays are a rare exception as sustained …

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The role of attention in perceptual biases in patients with schizophrenia spectrum disorder and healthy controls

Alexander C. Schütz, Tilo Kircher, Benjamin Straube

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The role of attention in perceptual biases in patients with schizophrenia spectrum disorder and healthy controls

Alexander C. Schütz, Tilo Kircher, Benjamin Straube

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Vertex-wise cortical abnormalities in major depressive disorder from 64 cohorts from the DIRECT and ENIGMA MDD consortia

Chao‐Gan Yan, Zi Wang, Laura K. M. Han, Nina Alexander et autres

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Predictive visual uncertainty around moving trajectories influences causality judgments in launching displays

Lina Eicke-Kanani, Fabian Tatai, Lukas Rosenberger, Christina Schmitter et autres

Michotte's 'launching displays' are animations of collision-like interactions between two objects that elicit a stable and robust impression that one object, the launcher, caused another object, the target, to move. Although it is well-known that unexpected disruptions of movement continuation between launcher …

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The relationship between psychopathology and neurocognitive functioning in affective and psychotic disorders: A multimodal Bayesian network analysis

Marlon Westhoff, Max Berg, Frederike Stein, Winfried Rief et autres

BACKGROUND: Affective and psychotic disorders share overlapping symptom constellations, environmental and genetic risk factors, and neurocognitive profiles. However, the nature of this association is not well understood, and accumulating evidence suggests a dimensional rather than categorical distinction between healthy and clinical populations. …

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