Masanao Sasaki

Exploring the association between happy hypoxia and Coronavirus disease 2019 in the triage phase

Mihiro Kaga, Masanao Sasaki, Takahiro Masuda, Hiroyuki Satō et autres

BACKGROUND: Patients with severe coronavirus disease 2019 (COVID-19) have been reported to show hypoxia without displaying typical clinical signs or symptoms, called "happy hypoxia." To explore the potential of happy hypoxia as a distinctive symptom of COVID-19, we compared vital signs in …

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Trends, costs, and complications associated with after-hours surgery and unscheduled hospitalization in spinal surgery

Tomoyuki Tanaka, Masanao Sasaki, Junya Katayanagi, Akihiko Hirakawa et autres

Aims: The escalating demand for medical resources to address spinal diseases as society ages is an issue that requires careful evaluation. However, few studies have examined trends in spinal surgery, especially unscheduled hospitalizations or surgeries performed after hours, through large databases. Our …

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Optimization of Endoscopic Ultrasound Characteristics in the Diagnosis of Malignant Intraductal Papillary Mucinous Neoplasm

Masanori Kobayashi, Mao Niimi, Hiromune Katsuda, Keiichi Akahoshi et autres

OBJECTIVES: Endoscopic ultrasound (EUS) is an excellent diagnostic tool that provides high-resolution images of pancreatic cystic lesions. However, its role in the diagnosis of malignant intraductal papillary mucinous neoplasm (IPMN) remains limited and unclear. We aimed to determine the usefulness of this …

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How Much More Efficient Are Adaptive Platform Trials Than Multiple Stand‐Alone Trials? A Comprehensive Simulation Study for Streamlining Drug Development During a Pandemic

Masanao Sasaki, Hiroyuki Sato, Yukari Uemura, Ayako Shimbara Mikami et autres

With the coronavirus disease 2019 (COVID-19) pandemic, there is growing interest in utilizing adaptive platform clinical trials (APTs), in which multiple drugs are compared with a single common control group, such as a placebo or standard-of-care group. APTs evaluate several drugs for …

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Self-organized clustering, prediction, and superposition of long-term cognitive decline from short-term individual cognitive test scores in Alzheimer's disease

Hiroyuki Sato, Keisuke Suzuki, Atsushi Hashizume, Ryoichi Hanazawa et autres

Progressive cognitive decline spanning across decades is characteristic of Alzheimer's disease (AD). Various predictive models have been designed to realize its early onset and study the long-term trajectories of cognitive test scores across populations of interest. Research efforts have been geared towards …

Imaging predictors of clinical outcomes after endovascular treatment in MRI-selected patients with acute basilar artery occlusion

Sakyo Hirai, Akihiro Hirakawa, Kyohei Fujita, Tadahiro Ishiwada et autres

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Comparison of decompression, decompression plus fusion, and decompression plus stabilization: a long-term follow-up of a prospective, randomized study

Hiroyuki Inose, Tsuyoshi Kato, Masanao Sasaki, Yu Matsukura et autres

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TWO CASES INFANTILE PERCEPTIVE DEAFNESS RELIEVED BY THE TREATMENT OF THE NASOPHARYNX

Hirokazu Shibui, Masanao Sasaki, M. IDEMITSU, Y. Yatomi

Case 1. 6 years old girl. On the hearing test, her both perceptive organs of inner ears was impaired, and hearing loss was about 60db. After adenotomy, the patient's sujective symptoms, such as otalgia, tinnitus and deafness diappeared promptly. Her hearing acuity …

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THE VELOCITY OF PROGRESSING WAVE ALONG THE BASILAR MEMBRANE

Masanao Sasaki

In order to verify the calculated velocities, the author observed with two beam oscilloscope the phase differences between the cochlear microphonics from two paris of electrodes which were inserted into the scalae and apart each other about 2 to 1.4mm.along the cochlear …

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