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Higher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial

Obbina Abani, Amr E. Abbas, Fatima H. Abbas, Jaffar Abbas et autres

Background: Low dose corticosteroids (e.g., 6 mg dexamethasone) have been shown to reduce mortality for hypoxic COVID-19 patients. We have previously reported that higher dose corticosteroids cause harm in patients with clinical hypoxia but not receiving ventilatory support (the combination of non-invasive …

E. coli O157 phage type 21/28 outbreak in North Cumbria associated with pasteurized milk

Suzanne Goh, C Newman, Margaret A. Knowles, F. J. Bolton et autres

In March 1999, a large community outbreak of Escherichia coli O157 infection occurred in North Cumbria. A total of 114 individuals were reported to the Outbreak Control Team (OCT); 88 had laboratory confirmed E. coli O157. Twenty-eight (32%) of the confirmed cases …

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CAMPYLOBACTER ENTERITIS ASSOCIATED WITH CONSUMPTION OF RAW GOAT'S MILK

D. N. Hutchinson, F. J. Bolton, W.C.N. Jelley, W.G. Mathews et autres

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Evidence of udder excretion ofCampylobacter jejunias the cause of milk-borne campylobacter outbreak

D. N. Hutchinson, F. J. Bolton, P. M. Hinchliffe, H. C. Dawkins et autres

We describe a community outbreak of campylobacter enteritis associated with the consumption of untreated milk, apparently contaminated by two cows with campylobacter mastitis. The outbreak occurred in two phases. Strains of Campylobacter jejuni of the Penner serogroup complex 4, 13, 16, 50 …

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Outbreak of bovine mastitis associated with Corynebacterium bovis

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Condemnation of sheep livers probably due to ascariasis

E.D. Borland, I. Keymer, D. Counter

Salmonella dublin infection in self contained dairy herds in East Anglia: excretion at calving

D. Counter, Emily Gibson

Salmonella dublin was isolated from 14 (0.4 per cent) of 3656 rectal swabs taken from adult cattle in 20 self-contained East Anglian dairy herds with a history of the infection in calves. When 1486 calvings in these herds were monitored, the organism …

The examination of milk samples for inhibitory substances following dry cow therapy with cephalonium

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A severe outbreak of bovine mastitis assoicated with Mycoplasma bovigenitalium and Acholeplasma laidlawii

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An outbreak of clinical mastitis is described in which 75 cows of a herd of 200 Friesian cows were affected in one or more quarters over a period of three months. Sixty animals failed to return to normal despite various intramammary and …

Transmissible gastroenteritis in pigs: some observations on laboratory aids to diagnosis

N.C.L. Giles, E.D. Borland, D. Counter, Eric Gibson

Thirty seven piglets with transmissible gastroenteritis (TGE) and 41 with other enteric diseases were examined for evidence of villous atrophy and reduced lactase activity. Widespread villous atrophy appeared indicative of TGE whereas normal lactase activity tended to exclude this possibility. However, both …

An incident of water intoxication in calves

Eric S. Gibson, D. Counter, Erin W Barnes

An outbreak of mycotic abortion apparently due to mould-infested sugar beet pulp

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