Rachel A. Scheperle

Comparative spatiotemporal dynamics of access resistance, polarization impedance, and nested bipolar impedance in standard and dexamethasone-eluting electrode arrays

Uzair A. Khan, Alexander D. Claussen, Bruce J. Gantz, Marlan R. Hansen et autres

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Longitudinal Acoustic Threshold and Concurrent Electrode Impedance Changes After Cochlear Implantation With Lateral Wall Electrode Arrays

Meggan Lind, Camille C. Dunn, Alexander D. Claussen, Bruce J. Gantz et autres

PURPOSE: To investigate changes in hearing sensitivity post cochlear implantation with MED-EL and Advanced Bionics (AB) lateral wall electrode arrays, with a focus on characterizing delayed onset hearing loss (doHL) and concurrent electrode impedance changes. METHODS: A retrospective review of 96 adult …

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Robotic‐Assisted Electrode Array Insertion Improves Stability of Acoustic Hearing Thresholds

Ubaid Khan, Rachel A. Scheperle, Grant Podhajsky, Meggan Lind et autres

OBJECTIVE(S): Robotic-assisted electrode array (EA) insertion is a promising technique that may enhance preservation of residual acoustic hearing after cochlear implant (CI) surgery. The purpose of this study is to evaluate the impact of robotic-assisted EA insertion on rates of delayed-onset hearing …

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Interaural correlation of acoustic hearing preservation following sequential cochlear implantation

Arminé Kocharyan, Carolina Chu, Rustin Kashani, Rachel A. Scheperle et autres

Introduction Compared to unilateral cochlear implantation, bilateral cochlear implantation demonstrates multiple advantages in speech understanding in noise and sound localization, especially when acoustic hearing is preserved in both ears. However, outcomes and factors influencing acoustic hearing preservation following cochlear implant (CI) remains …

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Spatiotemporal Dynamics of Cochlear Implant Electrode Impedance in Standard and Dexamethasone-Eluting Electrode Arrays

Uzair A. Khan, Amy S. Bussa, Jacob Oleson, Alexander D. Claussen et autres

OBJECTIVE: To evaluate the spatiotemporal dynamics of cochlear implant electrode impedance in standard and dexamethasone-eluting electrode arrays (Dex-EA). STUDY DESIGN: Prospective, double-arm study. SETTING: Single tertiary referral center. PATIENTS: Thirty-one (17 control and 14 experimental) subjects meeting Food and Drug Administration criteria …

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Electrode impedance dynamics in sequential cochlear implant users: insights into cochlear immunity

Eva L. Rasche, Jacob Oleson, Rachel A. Scheperle, Marlan R. Hansen

Introduction Cochlear implant outcomes can be limited due to immunologically mediated intracochlear foreign body responses, resulting in new bone growth and fibrosis. Minimal consideration has been given to the possible role of immunological memory in modulating this response in sequentially implanted patients. …

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Dexamethasone-eluting cochlear implants reduce inflammation and foreign body response in human and murine cochleae

Muhammad Taifur Rahman, Brian Mostaert, Peter Eckard, Shakila Mahmuda Fatima et autres

The inflammatory foreign body response (FBR) following cochlear implantation (CI) can negatively impact CI outcomes, including increased electrode impedances. This study aims to investigate the long-term efficacy of dexamethasone-eluting cochlear implant and locally delivered dexamethasone, a potent anti-inflammatory glucocorticoid, on the intracochlear …

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Robotic‐Assisted Electrode Array Insertion Improves Rates of Hearing Preservation

Ubaid Khan, Camille C. Dunn, Rachel A. Scheperle, Jacob Oleson et autres

OBJECTIVE(S): Robotic-assisted electrode array (EA) insertion is a promising technique that may enhance hearing preservation in cochlear implant (CI) surgery. The purpose of our study is to understand the extent to which robotic-assisted EA insertion improves hearing preservation. METHODS: Twenty-four adult patients …

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Cochlear implants with dexamethasone-eluting electrode arrays reduce foreign body response in a murine model of cochlear implantation and human subjects

Muhammad Taifur Rahman, Brian Mostaert, Peter Eckard, Shakila Mahmuda Fatima et autres

Abstract The inflammatory foreign body response (FBR) following cochlear implantation (CI) can negatively impact CI outcomes, including increased electrode impedances. This study aims to investigate the long-term efficacy of dexamethasone eluting cochlear implant and locally delivered dexamethasone, a potent anti-inflammatory glucocorticoid on …

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Evaluating Changes in Adult Cochlear Implant Users’ Brain and Behavior Following Auditory Training

Eun Kyung Jeon, Virginia Driscoll, Bruna S. Mussoi, Rachel A. Scheperle et autres

OBJECTIVES: To describe the effects of two types of auditory training on both behavioral and physiological measures of auditory function in cochlear implant (CI) users, and to examine whether a relationship exists between the behavioral and objective outcome measures. DESIGN: This study …

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Combining Intraoperative Electrocochleography with Robotics-Assisted Electrode Array Insertion

Rustin Kashani, Arminé Kocharyan, Douglas M. Bennion, Rachel A. Scheperle et autres

OBJECTIVE: To describe the use of robotics-assisted electrode array (EA) insertion combined with intraoperative electrocochleography (ECochG) in hearing preservation cochlear implant surgery. STUDY DESIGN: Prospective, single-arm, open-label study. SETTING: All procedures and data collection were performed at a single tertiary referral center. …

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Evaluation of Real-Time Intracochlear Electrocochleography for Guiding Cochlear Implant Electrode Array Position

Rachel A. Scheperle, Christine P. Etler, Jacob Oleson, Camille C. Dunn et autres

This study evaluates intracochlear electrocochleography (ECochG) for real-time monitoring during cochlear implantation. One aim tested whether adjusting the recording electrode site would help differentiate between atraumatic and traumatic ECochG amplitude decrements. A second aim assessed whether associations between ECochG amplitude decrements and …

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