Antonella Ampollini

Correction: Navone et al. Role of Luteolin as Potential New Therapeutic Option for Patients with Glioblastoma Through Regulation of Sphingolipid Rheostat. Int. J. Mol. Sci. 2024, 25, 130

Stefania Elena Navone, Laura Guarnaccia, Massimiliano D. Rizzaro, Laura Begani et autres

In the original publication [...].

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Cognitive effects of adaptive deep brain stimulation in Parkinson’s disease: stability without risk

Roberta Ferrucci, Fabiana Ruggiero, Edoardo Nicolò Aiello, Sara Marceglia et autres

BACKGROUND: Adaptive deep brain stimulation (aDBS) is a closed-loop system that adjusts stimulation based on patient biomarkers. This study evaluated the cognitive safety of aDBS in Parkinson's disease (PD). METHODS: Sixteen PD patients with bilateral subthalamic DBS underwent cognitive assessments (attention, language, …

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Cognitive Effects of Adaptive Deep Brain Stimulation in Parkinson’s Disease: Stability Without Risk

Roberta Ferrucci, Fabiana Ruggiero, Edoardo Nicolò Aiello, Sara Marceglia et autres

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Volumetric Changes of Basal Ganglia in patients with Parkinson Disease after Deep Brain Stimulation: Neurodegeneration or Neuroplasticity?

Massimiliano Domenico Rizzaro, Luigi Schisano, Antonella Ampollini, Luigi Gianmaria Remore et autres

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Testing calpain inhibition in tumor endothelial cells: novel targetable biomarkers against glioblastoma malignancy

Laura Guarnaccia, Stefania Elena Navone, Laura Begani, Emanuela Barilla et autres

Introduction Glioblastoma IDH-wildtype (GBM) is the most malignant brain tumor in adults, with a poor prognosis of approximately 15 months after diagnosis. Most patients suffer from a recurrence in <1 year, and this renders GBM a life-threatening challenge. Among molecular mechanisms driving …

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Role of Luteolin as Potential New Therapeutic Option for Patients with Glioblastoma through Regulation of Sphingolipid Rheostat

Stefania Elena Navone, Laura Guarnaccia, Massimiliano Domenico Rizzaro, Laura Begani et autres

Glioblastoma (GBM) is the most aggressive brain tumor, still considered incurable. In this study, conducted on primary GBM stem cells (GSCs), specifically selected as the most therapy-resistant, we examined the efficacy of luteolin, a natural flavonoid, as an anti-tumoral compound. Luteolin is …

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A Targeted Next-Generation Sequencing Panel to Genotype Gliomas

Maria Guarnaccia, Laura Guarnaccia, Valentina La Cognata, Stefania Elena Navone et autres

Gliomas account for the majority of primary brain tumors. Glioblastoma is the most common and malignant type. Based on their extreme molecular heterogeneity, molecular markers can be used to classify gliomas and stratify patients into diagnostic, prognostic, and therapeutic clusters. In this …

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