Huanzhen Liu

Research on High-dimensional System-level Calibration of Platform Inertial Navigation Systems on a Dual-axis Centrifuge

Tianyi Xie, Shunqing Ren, Huanzhen Liu, Chuankun Han et autres

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Integrative transcriptomic and metabolomic profiling reveals candidate SWEET and SUT transporters associated with nectar sugar accumulation in Tilia amurensis

Wenjun Ma, Huanzhen Liu, Chunming Li, Zhaoning Wang et autres

Floral nectar sugar composition is a key trait underlying plant–pollinator interactions and honey production, yet the molecular basis of natural variation in nectar sugar accumulation remains poorly understood in woody nectar-producing species. Tilia amurensis is an important nectar-producing tree species in northeastern …

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Genetic Variation in Pulpwood Properties of Hybrid Larch Families and Their Progenies

Naizhong Hu, Jiaqi Huang, Guanghao Cao, Panke Yang et autres

This study aimed to elucidate the genetic variation patterns of hybrid larch during generational transitions, providing a theoretical basis for targeted genetic improvement and advanced hybrid breeding of pulpwood. Seven hybrid larch families and their progeny from the Qingshan National Larch Elite …

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Enhancing Cryopreservation Efficiency in Populus davidiana × P. tremuloides Shoot Tips: Optimization of Vitrification Protocols and Mechanistic Insights into Flavonoid-Mediated Stress Adaptation

Panke Yang, Zelin Li, Qi Yu, Yuandong Ma et autres

Cryopreservation is vital for conserving the elite germplasm of the hybrid poplar Populus davidiana × P. tremuloides, which is difficult to propagate conventionally. This study established optimized vitrification and encapsulation–vitrification protocols, achieving high regeneration rates of 85.91% and 79.70%, respectively, with confirmed …

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Chimeras co-targeting antigens and FcγRIIb trigger degradation of extracellular soluble proteins and pathological aggregates

Mingjuan Du, Na Li, Tianqi Li, Zhuoqian Zhao et autres

While the clinical utility of conventional antibody therapies is undeniable, their therapeutic potential is often constrained high antigen loads and the recycling of antibody-antigen complexes via neonatal Fc receptor (FcRn). Here, we present a platform, based on a design similar to bispecific …

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Effects of Different Plant Growth Regulators on Growth Physiology and Photosynthetic Characteristics of Pinus koraiensis Seedlings

Wenbo Zhang, Chunming Li, Zhenghua Li, Naizhong Hu et autres

Pinus koraiensis, as a keystone tree species, possesses immense economic and ecological value. However, the present cultivation of high-quality seedlings in Pinus koraiensis plantations remains hindered by prohibitively high costs and inadequate technological advancements. Additionally, the species’ prolonged growth cycle and low …

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PsnMYB30 Enhances Salt and Drought Stress Tolerance in Transgenic Tobacco

Yuting Wang, Msangi Shamsia Ally, Ruiqi Wang, Wenjing Yao et autres

Drought and salinity are two major environmental factors that severely limit plant growth and development. MYB functions as a transcription factor that is crucial in how plants respond to stress from adverse conditions. In this study, we identified a gene encoding Populus …

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A broadly neutralizing antibody recognizes a unique epitope with a signature motif common across coronaviruses

Lei Yan, Fulian Wang, Michelle L. Hill, Juliane Brun et autres

Cross-reactive antibodies targeting multiple epitopes have been identified in Sarbecoviruses, but the precise molecular mechanism(s) behind the crossreactivity remain poorly understood. Here, we isolate 3D1, a broadly neutralizing antibody (bnAb) derived from a human combinatorial antibody library targeting the conserved HR1 domain. …

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The crystal structure of coronavirus RBD-TMPRSS2 complex provides basis for the discovery of therapeutic antibodies

Zhuoqian Zhao, Qi Yang, Xiaoce Liu, Mengfei Li et autres

HCoV-HKU1, one of seven human coronaviruses (HCoVs) that have harmful effects on human health, accounts for a substantial portion of common cold cases and can cause severe respiratory diseases in certain populations. Currently, effective antiviral treatments against this virus are limited. Recently, …

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Second-order coefficient calibration method of accelerometer in platform inertial navigation system tested on double turntable centrifuge

Tianyi Xie, Huanzhen Liu, Yong-hui Qiao, Guowei Pan

This paper proposes a method of accurately calibrating the second-order coefficient of accelerometer in platform inertial navigation system(PINS) being calibrated by double turntable centrifuge. Firstly, the errors of specific force caused by the angular rate error about spindle system of the centrifuge …

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Structures of HCoV-OC43 HR1 Domain in Complex with Cognate HR2 or Analogue EK1 Peptide

Xin He, Huanzhen Liu, Guang Yang, Lei Yan

Human coronavirus OC43 (HCoV-OC43) is usually associated with common colds, but also related to severe disease in the frail. Its envelope glycoproteins spike (S) is responsible for host-cell attachment and membrane fusion. To understand the molecular basis of membrane fusion of HCoV-OC43, …

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Evaluation of Lonicera caerulea Cultivar Diversity Based on Phenotypic Traits and Nutrient Composition

Yu Qi, Chunming Li, Xueying Liang, An‐Qi Chen et autres

Lonicera caerulea L. has high nutritional and health value, and it is an important emerging small berry tree species. In this study, the morphology and nutrient composition of 60 cultivars were used to analyze and evaluate the diversity of the genus. Morphological …

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