Tienush Rassaf

Extracorporeal Membrane Oxygenation Complications Are Not Causal for Mortality in Patients With Infarct-Related Cardiogenic Shock: A Mediation Analysis of the Extracorporeal Life Support in Infarct-Related Cardiogenic Shock (ECLS-SHOCK) Trial

Tharusan Thevathasan, Mohamad Alyahoud, Anne Freund, İbrahim Akın et autres

OBJECTIVE: Recently published randomized controlled trials and an individual patient data meta-analysis showed that the routine use of venoarterial extracorporeal membrane oxygenation (VA-ECMO) did not reduce mortality compared with medical therapy alone in patients with acute myocardial infarction complicated by cardiogenic shock …

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DGK-Curriculum Onkologische Kardiologie

Lorenz Lehmann, Claudia Dorothea Baldus, Yvonne Bewarder, Judit Boda-Heggemann et autres

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ECG markers of left ventricular hypertrophy indicate response to mavacamten in hypertrophic obstructive cardiomyopathy

Florian Buehning, Tobias Lerchner, Julia Kirsten Vogel, Lizet van der Kolk et autres

BACKGROUND: Mavacamten has revolutionised the treatment of hypertrophic obstructive cardiomyopathy (HOCM) but requires frequent follow-up. Routine ECG may offer an accessible tool to indicate response to therapy. This study evaluates ECG-based indices of left ventricular hypertrophy (LVH) in patients with HOCM receiving …

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Propensity Matched Analysis of 14 French Suture‐ Versus Plug‐Based Vascular Closure During Transfemoral Transcatheter Aortic Valve Replacement (TAVR)

Tobias Lerchner, Lars Michel, Klaus A. Tiroch, Tienush Rassaf et autres

BACKGROUND: Plug-based vascular closure devices (Pb-VCD) and suture-based vascular closure devices (Sb-VCD) are used for percutaneous vascular access site closure during transcatheter aortic valve replacement (TAVR). Until now, no clear superiority of either device was shown in studies comparing 18 F VCDs …

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Teilstationäre Versorgung in universitären Kliniken für Kardiologie

Malte Kelm, Daniel Dürschmied, Stephan Achenbach, Johann Bauersachs et autres

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Association of Hemoglobin A1c Levels With All-Cause Mortality in Patients With Coronary Artery Disease

Iryna Dykun, Natalie Kappo, Jürgen Kampf, Olga Babinets et autres

BACKGROUND: Hemoglobin A1c (HbA1c) as a marker of long-term glycemic control is used for the diagnosis and assessment of treatment of diabetes mellitus. OBJECTIVES: The authors aimed to evaluate whether HbA1c levels would independently associate with long-term survival independent of the presence …

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Prevention of cancer-therapy related cardiac dysfunction

Elias Haj‐Yehia, Lars Michel, Raluca Ileana Mincu, Tienush Rassaf et autres

PURPOSE OF REVIEW: Introduction of modern cancer therapies has led to increased survival of affected patients. With this advantage, the incidence of cancer therapy-related cardiac dysfunction (CTRCD) has increased and reasonable prevention strategies become necessary. This review outlines the major approaches to …

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Bridging cardiology and oncology in the era of precision medicine

Tienush Rassaf

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Identifying prognostic factors in patients with cardiogenic shock undergoing VA-ECMO treatment: insights from ECLS-SHOCK using machine learning

Karl‐Patrik Kresoja, U Zweymer, İbrahim Akın, Tienush Rassaf et autres

Abstract Background/Introduction Venoarterial extracorporeal membrane oxygenation (VA-ECMO) has not been shown to reduce short-term mortality in patients with acute myocardial infarction complicated by cardiogenic shock. However, whether some patients might benefit from VA-ECMO remains to be cleared. Purpose To identify the impact …

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Impact of smoking on procedural outcomes and all-cause mortality following acute myocardial infarction: A misleading early-stage pseudoparadox with ultimately reduced survival

Mohammed Abusharekh, Jürgen Kampf, Iryna Dykun, Viktoria Backmann et autres

Background: Smoking has conflicting results on outcomes following acute myocardial infarction (AMI). We evaluated the independent influence of smoking status on patient outcomes. Methods: We included patients with AMI undergoing invasive coronary angiography with available self-reported smoking status. The incidence of death …

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Comprehensive strain assessment and mortality after acute myocardial infarction: a retrospective observational study based on the Essen Coronary Artery Disease registry

Viktoria Backmann, Iryna Dykun, Jürgen Kampf, Bastian Balcer et autres

BACKGROUND AND AIMS: Current ESC guidelines on the management of patients after acute myocardial infarction only include the evaluation of left ventricular (LV) function by assessment of the ejection fraction in addition to clinical risk scores to estimate the patient's prognosis. We …

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Outcome after ablation of atypical atrial flutter: Is induction a feasible approach?

Nadine Vonderlin, Johannes Siebermair, Amir Abbas Mahabadi, Dobromir Dobrev et autres

Background: Atypical atrial flutter (AAF) is an increasingly relevant clinical problem. Despite advancements in mapping and ablation techniques, the general management of these patients remain challenging especially when mapping cannot be performed during ongoing arrhythmia. There are no data whether induction of …

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