Laila Aldars‐García

Correction: HealthData@MAD-R&I: Protocol for Design and Development of a Regional Health Data Infrastructure to Enable Secondary Use of Health Data in Research and Innovation

Montserrat León‐García, Sergio Álvarez‐Pérez, Janire Gesto-Gómez, Clara Urbano-Molina et autres

[This corrects the article DOI: 10.2196/82815.].

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Exploration of fecal microbiota in newly diagnosed patients with inflammatory bowel disease using shotgun metagenomics

Macarena Orejudo, Manuel J. Gómez, Sabino Riestra, Montserrat Rivero et autres

Introduction: Dysbiosis is a key mechanism in inflammatory bowel disease (IBD) pathophysiology. Previous microbiota studies in IBD generally have involved patients treated with immunosuppressive agents, which can affect the results. We aimed to elucidate the fecal microbiota composition in newly diagnosed treatment-naïve …

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Aflatoxin B1 production: A time–water activity–temperature model

Sonia Marı́n, Laila Aldars‐García, Francisco Molino Gahete, Antonio J. Ramos et autres

Aspergillus flavus occurs as a contaminant of various foods and animal feeds and can produce the mycotoxin aflatoxin B1 that is a danger to human and animal health. Here, we develop models to predict the behaviour of A. flavus in maize extract …

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Serum and Urine Metabolomic Profiling of Newly Diagnosed Treatment-Naïve Inflammatory Bowel Disease Patients

Laila Aldars‐García, Rubén Gil‐Redondo, Nieves Embade, Sabino Riestra et autres

BACKGROUND AND AIMS: Inflammatory bowel disease (IBD) is a prevalent chronic noncurable disease associated with profound metabolic changes. The discovery of novel molecular indicators for unraveling IBD etiopathogenesis and the diagnosis and prognosis of IBD is therefore pivotal. We sought to determine …

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Metabolomics Insights into Inflammatory Bowel Disease: A Comprehensive Review

Laila Aldars‐García, Javier P. Gisbert, María Chaparro

Inflammatory bowel disease (IBD) is a chronic, complex relapsing disorder characterised by immune dysregulation, gut microbiota alteration, and disturbed intestinal permeability. The diagnosis and the management of IBD are challenging due to the recurrent nature and complex evolution of the disease. Furthermore, …

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DOP19 Urinary metabolome in newly diagnosed treatment-naïve Crohn’s Disease patients: Results from the IBDomics study

Laila Aldars‐García, Rubén Gil‐Redondo, Nieves Embade, Sabino Riestra et autres

Abstract Background The urinary metabolome of patients with Crohn’s disease (CD) differs significantly from healthy subjects and, among other features, reflects the specific gut dysbiosis affecting these patients. However, most of the studies included established and treated CD patients. Our aim was …

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Systematic Review: The Gut Microbiome and Its Potential Clinical Application in Inflammatory Bowel Disease

Laila Aldars‐García, María Chaparro, Javier P. Gisbert

Inflammatory bowel disease (IBD) is a chronic relapsing-remitting systemic disease of the gastrointestinal tract. It is well established that the gut microbiome has a profound impact on IBD pathogenesis. Our aim was to systematically review the literature on the IBD gut microbiome …

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The Interplay between Immune System and Microbiota in Inflammatory Bowel Disease: A Narrative Review

Laila Aldars‐García, Alicia C Marín, María Chaparro, Javier P. Gisbert

The importance of the gut microbiota in human health is currently well established. It contributes to many vital functions such as development of the host immune system, digestion and metabolism, barrier against pathogens or brain–gut communication. Microbial colonization occurs during infancy in …

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Assessment of intraspecies variability in fungal growth initiation of Aspergillus flavus and aflatoxin B1 production under static and changing temperature levels using different initial conidial inoculum levels

Laila Aldars‐García, Sonia Marı́n, Vicente Sanchís, Naresh Magan et autres

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Probability models for growth and aflatoxin B 1 production as affected by intraspecies variability in Aspergillus flavus

Laila Aldars‐García, María Berman-Riu, J. Ortiz‐Solà, Antonio J. Ramos et autres

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Time-course of germination, initiation of mycelium proliferation and probability of visible growth and detectable AFB1 production of an isolate of Aspergillus flavus on pistachio extract agar

Laila Aldars‐García, Vicente Sanchís, Antonio J. Ramos, Sonia Marı́n

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Single vs multiple-spore inoculum effect on growth kinetic parameters and modeled probabilities of growth and aflatoxin B1 production of Aspergillus flavus on pistachio extract agar

Laila Aldars‐García, Vicente Sanchís, Antonio J. Ramos, Sonia Marı́n

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