2018
article
OpenAlex
Linda Roney, Christine McKenna
Trauma has a greater impact on morbidity and mortality than all other disease processes in the pediatric population; yet, there is a gap in the literature related to the scientific basis for educating and researching future practice. The purpose of this research …
us
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2018
article
OpenAlex
Christine M. Leeper, Christine McKenna, Barbara A. Gaines
BACKGROUND: Hypotension is a late finding in pediatric shock despite significant blood loss; consequently, recognition of hemodynamic compromise can be delayed. We sought to describe the impact of late stage shock in children, indicated by hypotension or trauma bay blood transfusion, and …
kr, us
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2017
article
OpenAlex
Christine M. Leeper, Matthew D. Neal, Christine McKenna, Timothy R. Billiar et autres
us
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2017
article
OpenAlex
Christine M. Leeper, Matthew D. Neal, Christine McKenna, Barbara A. Gaines
OBJECTIVE: To trend fibrinolysis after injury and determine the influence of traumatic brain injury (TBI) and massive transfusion on fibrinolysis status. BACKGROUND: Admission fibrinolytic derangement is common in injured children and adults, and is associated with poor outcome. No studies examine fibrinolysis …
us
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2017
article
OpenAlex
Christine M. Leeper, Isam W. Nasr, Abigail Koff, Christine McKenna et autres
us
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2016
article
OpenAlex
Christine M. Leeper, Christine McKenna, Barbara A. Gaines
us
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2016
article
OpenAlex
Christine M. Leeper, Matthew D. Neal, Christine McKenna, Jason L. Sperry et autres
BACKGROUND: Abnormalities in fibrinolysis are common and associated with increased mortality in injured adults. While hyperfibrinolysis (HF) and fibrinolysis shutdown (SD) are potential prognostic indicators and treatment targets in adults, these derangements are not well described in a pediatric trauma cohort. METHODS: …
us, Égypte
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2016
article
OpenAlex
Christine M. Leeper, Matthew Kutcher, Isam W. Nasr, Christine McKenna et autres
BACKGROUND: While our understanding of acute traumatic coagulopathy (ATC) in adults is advancing, the pediatric literature on ATC is limited. Children have a unique injury profile and physiologic response to trauma; however, the impact of this phenomenon on ATC has not been …
us
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2015
article
OpenAlex
Christine M. Leeper, Isam W. Nasr, Christine McKenna, Rachel P. Berger et autres
BACKGROUND: Victims of abusive head trauma have poor outcomes compared with other injured children. There is often a delay in diagnosis because these young patients are unable to communicate with health care providers. These critically injured patients would benefit from early identification …
us
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2014
article
OpenAlex
Nancy Kassam‐Adams, Susan Rzucidlo, Marie Campbell, Grace Good et autres
us
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2012
article
OpenAlex
Sohail R. Shah, Christine McKenna, Marianne Miller, Barbara L. Shultz et autres
BACKGROUND: All-terrain vehicle (ATV)-related injuries are a significant source of pediatric trauma. We hypothesized that these injuries are caused by poor safety behavior. To test this hypothesis, we surveyed both injured and uninjured ATV riders. METHODS: A prospective convenience sample-based survey was …
us
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2012
article
OpenAlex
Richard A. Falcone, Lynn Haas, Eileen King, Suzanne Moody et autres
BACKGROUND: The American College of Surgeons has defined six minimum activation criteria (ACS-6) for the highest level of trauma activations at trauma centers. The verification criteria also allow for the inclusion of additional criteria at the institution's discretion. The purpose of this …
us
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