Andrea Panunzi

Therapeutic footwear in patients with diabetes: a position statement from the Italian diabetic foot study group

Laura Giurato, Alessia Scatena, Roberto De Giglio, Giuseppe Murdolo et autres

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The Immune-Centric Revolution Translated into Clinical Application: Peripheral Blood Mononuclear Cell (PBMNC) Therapy in Diabetic Patients with No-Option Critical Limb-Threatening Ischemia (NO-CLTI)—Rationale and Meta-Analysis of Observational Studies

Laura Rehak, Laura Giurato, Matteo Monami, Marco Meloni et autres

Chronic limb-threatening ischemia (CLTI), the most advanced form of peripheral arterial disease (PAD), is the comorbidity primarily responsible for major lower-limb amputations, particularly for diabetic patients. Autologous cell therapy has been the focus of efforts over the past 20 years to create …

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Risk Factors for Ulcer Recurrence in Diabetic Patients Managed by an Integrated Foot Care Protocol

Laura Giurato, Andrea Panunzi, Marco Meloni, Chiara Pecchioli et autres

The aim of our study was to identify risk factors for the recurrence of diabetic foot ulcers (DFUs) in a selected population of patients in secondary prevention treated, according to International Guidelines, with an integrated foot care protocol by a referral diabetic …

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Results of a prospective observational study of autologous peripheral blood mononuclear cell therapy for no-option critical limb-threatening ischemia and severe diabetic foot ulcers

Andrea Panunzi, Fabiana Madotto, Elena Sangalli, Federica Riccio et autres

Abstract Background Cell therapy with autologous peripheral blood mononuclear cells (PB-MNCs) may help restore limb perfusion in patients with diabetes mellitus and critical limb-threatening ischemia (CLTI) deemed not eligible for revascularization procedures and consequently at risk for major amputation (no-option). Fundamental is …

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Bioactive Glass in a Multi Drug Resistance Osteomyelitis in Diabetic Foot: Case Report

Andrea Panunzi, Laura Giurato, Marco Meloni, Luigi Uccioli

Diabetic foot osteomyelitis (DFO) is a clinical problem with high risk of amputation. The treatment of DFO is still an unsolved challenge. Surgical therapy, antibiotic therapy or conservative treatment are still debated for the timing and the consequences. Long antibiotic therapies expose …

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Effectiveness of Sucrose Octasulfate Dressing in the Treatment of Neuro-Ischaemic Diabetic Foot Heel Ulcers: A Retrospective Single arm Study

Marco Meloni, Laura Giurato, Andrea Panunzi, Alfonso Bellia et autres

The study aimed to evaluate the effectiveness of the use of sucrose octasulfate impregnated dressing (TLC-NOSF [Technology Lipido-Colloid-Nano-OligoSaccharide Factor]) in the management of persons with neuro-ischaemic heel diabetic foot ulcers (DFUs). Consecutive patients who referred for an active non-infected neuro-ischaemic heel DFU …

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The Immune-Centric Revolution in the Diabetic Foot: Monocytes and Lymphocytes Role in Wound Healing and Tissue Regeneration—A Narrative Review

Laura Rehak, Laura Giurato, Marco Meloni, Andrea Panunzi et autres

Monocytes and lymphocytes play a key role in physiologic wound healing and might be involved in the impaired mechanisms observed in diabetes. Skin wound macrophages are represented by tissue resident macrophages and infiltrating peripheral blood recruited monocytes which play a leading role …

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Foot Revascularization Avoids Major Amputation in Persons with Diabetes and Ischaemic Foot Ulcers

Marco Meloni, Daniele Morosetti, Laura Giurato, Matteo Stefanini et autres

The study aims to evaluate the effectiveness of foot revascularization in persons with diabetic foot ulcers (DFUs) and below-the-ankle (BTA) arterial disease. Consecutive patients referred for a new active ischaemic DFU requiring lower limb revascularization were considered. Among those, only patients with …

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Peripheral Arterial Disease in Persons with Diabetic Foot Ulceration: a Current Comprehensive Overview

Marco Meloni, Valentina Izzo, Daniele Morosetti, Da Ros Valerio et autres

In developed countries, the prevalence of persons with diabetes and peripheral arterial disease (PAD) is approximately 50%. The presence of PAD is associated with non-healing ulcers, major amputation, cardiovascular morbidity, and mortality. It is estimated that persons with diabetes, foot ulceration and …

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Advancement of thyroid surgery video recording: A comparison between two full HD head mounted video cameras

Andrea Ortensi, Andrea Panunzi, Silvia Trombetta, Alberto Cattáneo et autres

Background The aim of this study was to test two different video cameras and recording systems used in thyroid surgery in our Department. This is meant to be an attempt to record the real point of view of the magnified vision of …

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A mosaic pattern of INI1/SMARCB1 protein expression distinguishes Schwannomatosis and NF2-associated peripheral schwannomas from solitary peripheral schwannomas and NF2-associated vestibular schwannomas

Rosario Caltabiano, Gaetano Giuseppe Magro, Agata Polizzi, Andrea D. Praticò et autres

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Microsurgical approach for unusual and unexpected malignant fibrous histiocytoma of the forearm: A case report

Valerio D’Orazi, Andrea Panunzi, Marco Paoloni, Alice Ortensi et autres

Soft tissue sarcomas are rare tumors with a dismal prognosis. Among the most common histological types of sarcomas of the extremities, malignant fibrous histiocytoma (MFH) is the one with the highest incidence. Surgery is considered to be the first choice of treatment …

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