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Profil bibliographique

Surendra Poudel

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5Publications signalées
103Citations signalées
2Affiliations récentes

Les institutions déclarées

Les domaines associés

Pain Mechanisms and TreatmentsDrug Solubulity and Delivery SystemsHydrogels: synthesis, properties, applicationsCentral Venous Catheters and HemodialysisWound Healing and Treatments

Les publications récentes

Accès ouvert 2025 article OpenAlex

Nitric Oxide-Releasing Thixotropic Hydrogels as Antibacterial and Hemocompatible Catheter Locks

W.Y. Li, Loren K. Liebrecht, Surendra Poudel, Rebecca Goodhart et autres

Catheters are indispensable medical tools for accessing blood vessels, hollow organs, and body cavities to facilitate medication delivery and fluid drainage. However, they also serve as major entry points for bacterial contamination and trigger foreign body responses, necessitating locking strategies that are …

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0 citations ACS Biomaterials Science & Engineering
Accès ouvert 2025 preprint OpenAlex

Nitric Oxide-Releasing Thixotropic Hydrogels as Antibacterial and Hemocompatible Catheter Locks

W.Y. Li, Loren K. Liebrecht, Surendra Poudel, Rebecca Goodhart et autres

Abstract Catheters are indispensable medical tools for accessing blood vessels, hollow organs, and body cavities to facilitate medication delivery and fluid drainage. However, they also serve as major entry points for bacterial contamination and trigger foreign body responses, necessitating locking strategies that …

us (code pays fourni par la source)

0 citations bioRxiv (Cold Spring Harbor Laboratory)
Accès ouvert 2025 article OpenAlex

New PPARα Agonist A190-Loaded Microemulsion for Chemotherapy-Induced Peripheral Neuropathy

Rudra Pangeni, Surendra Poudel, Sara M Herz, Grant Berkbigler et autres

Chemotherapy-induced peripheral neuropathy (CIPN) is a serious side effect of anticancer agents with limited effective preventive or therapeutic interventions. Although fenofibrate, a peroxisome proliferator-activated receptor-alpha (PPARα) agonist, has demonstrated neuroprotective and analgesic properties, its clinical utility is hindered by low receptor affinity, …

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5 citations Molecular Pharmaceutics
Accès ouvert 2021 article OpenAlex

Developing pH-Modulated Spray Dried Amorphous Solid Dispersion of Candesartan Cilexetil with Enhanced In Vitro and In Vivo Performance

Surendra Poudel, Dong Wuk Kim

Candesartan cilexetil (CC), a prodrug and highly effective antihypertensive agent, is a poorly soluble (BCS Class II) drug with limited bioavailability. Here, we attempted to improve CC’s bioavailability by formulating several CC-loaded amorphous solid dispersions with a hydrophilic carrier (PVPK30) and pH …

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34 citations Pharmaceutics

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