Sandra Vreman

Natural SARS-CoV-2 infection in farmed minks (Neovison vison) causes lung pathology, systemic viral spread, and transmission risk, even in asymptomatic animals

Sandra Vreman, Giuseppe Giglia, Robert-Jan Molenaar, Renate Hakze-van der Honing et autres

Introduction In 2020, the first disease outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in farmed minks (Neovison vison) was reported in the Netherlands, followed by outbreaks in other countries. The disease in minks is characterized by interstitial pneumonia and viral …

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Natural SARS-CoV-2 infections in farmed minks results in severe lung pathology and high viral loads in multiple organs

Sandra Vreman, Giuseppe Giglia, Robert Jan Molenaar, Renate Hakze et autres

nl (code pays fourni par la source)

Transmission and pathogenicity in ferrets after experimental infection with HPAI H5N1 clade 2.3.4.4B viruses

Léa Bordes, Nora M. Gerhards, Mikeal L. Roose, Sandra Venema et autres

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Pericarditis in vaccinated pigs protected against African swine fever virus challenge

Sandra Vreman, Nadia Oreshkova, L. J. B. Peeters, Nora M. Gerhards et autres

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Comparative avian influenza immuno-pathology between chickens, Pekin ducks and Eurasian wigeons infected with Dutch H5 HPAI strains of clade 2.3.4.4

Sandra Vreman, Evelien A. Germeraad, Mikeal L. Roose, S. Venema-Kemper et autres

nl (code pays fourni par la source)

Transmission and pathogenicity in ferrets after experimental infection with HPAI clade 2.3.4.4b H5N1 viruses

Luca Bordes, Nora M. Gerhards, Marit Roose, Sandra Venema et autres

A marked increase in the incidence of mortality amongst wild mammals attributed to infection with highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b viruses was observed in Europe in 2021. Neurological signs and high viral antigen levels in the brain of infected …

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Hamsters immunized with formalin-inactivated SARS-CoV-2 develop accelerated lung histopathological lesions and Th2-biased response following infection

Rineke de Jong, Sandra Vreman, Katrin E. Wiese, Nora M. Gerhards et autres

One of the concerns regarding vaccine safety during the COVID-19 pandemic was the potential manifestation of vaccine-associated enhancement of disease (VAED) upon SARS-CoV-2 infection. To investigate the suitability of the Syrian hamster model to test for VAED, we immunized animals with an …

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The kinetics of maternal and self-developed Streptococcus suis-specific antibodies

Sandra Vreman, Rutger Jansen, Mikael Bastian, Patricia Beckers et autres

BACKGROUND: Streptococcus suis (S. suis) infections are responsible for a large disease burden in piglets during the nursery phase, compromising animal welfare and increasing antibiotic use. The immune gap caused by decreased maternal-derived antibodies (MDA) and insufficient levels or functionality of acquired …

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Comparative Histology and Proteome Analysis of Human and Mink Sars-Cov-2 Infected Lung Tissue

Boaz V Lopuhaä, Coşkun Güzel, Giuseppe Giglia, Naomi D. de Bruijn et autres

nl, it (code pays fourni par la source)

Hamsters immunized with formalin-inactivated SARS- CoV-2 develop accelerated lung histopathological lesions and Th2-biased response following infection

Rineke de Jong, Sandra Vreman, Katrin E. Wiese, Nora M. Gerhards et autres

nl, gb (code pays fourni par la source)

Experimental infection of chickens, Pekin ducks, Eurasian wigeons and Barnacle geese with two recent highly pathogenic avian influenza H5N1 clade 2.3.4.4b viruses

Luca Bordes, Evelien A. Germeraad, Marit Roose, Nadiah M. H. A. van Eijk et autres

Multiple genotypes of highly pathogenic avian influenza (HPAI) H5 clade 2.3.4.4b viruses have caused epizootics in wild birds and poultry. The HPAI H5N1 genotype C virus caused a modest epizootic, whereas the occurrence of the HPAI H5N1 genotype AB virus in 2021 …

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The kinetics of maternal and self-developed Streptococcus suis-specific antibodies

Sandra Vreman, Rutger Jansen, Mikael Bastian, Patricia Beckers et autres

nl, br (code pays fourni par la source)