Yi‐An Lin

Affordances Drive Forum User Goals And Contributions

Tzu-Ling Huang, Yi‐An Lin, Hsin-Yi Huang, Alan Dennis et autres

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Online Game Features and Player Immersive Use

Shih‐I Tai, Ching‐I Teng, Yi‐An Lin, Gen‐Yih Liao et autres

Games are popular information systems (IS) that deeply immerse users, yet the game features enabling immersion remain unclear. Drawing on the theory of interactive media effects and flow theory, this study develops a framework linking game features to four immersion capabilities. We …

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Treatment Patterns and Outcomes in Patients with Advanced Biliary Tract Cancers Treated with Gemcitabine-Based Chemotherapy: A Retrospective Study

Farshid Dayyani, Heide A. Stirnadel-Farrant, Jenny Hu, Yi‐An Lin et autres

Background: Historically, the standard of care for advanced biliary tract cancers (aBTCs) was gemcitabine plus cisplatin (GemCis). Immunotherapy plus GemCis is now recommended as a first-line treatment for aBTCs. Whether patients can tolerate eight cycles of GemCis in clinical practice, as per …

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Determination Of Urinary Higenamine Excretion After Higenamine-containing Chinese Herbal Medicine Administration

Yi‐An Lin, Ching-Hsuang Hsu, Chin‐Chuan Tsai, Mei‐Chich Hsu

Higenamine, a compound found in many Chinese herbs, is classified as a banned substance by the World Anti-Doping Agency (WADA). Chinese herbal medicine is commonly used in traditional Chinese medicine for treating various diseases. Therefore, it is important to evaluate the potential …

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Treatment patterns of gemcitabine-based chemotherapy in patients with de novo and recurrent advanced biliary tract cancer.

Farshid Dayyani, Heide A. Stirnadel-Farrant, Jenny Hu, Yi‐An Lin et autres

454 Background: Biliary tract cancers (BTC) are often diagnosed at advanced stages (aBTC) when prognosis is poor. In the Phase 3 TOPAZ-1 study (NCT03875235), durvalumab plus gemcitabine and cisplatin (GemCis) significantly improved overall survival versus placebo plus GemCis. To better understand the …

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Identification of characteristics predictive of long-term survival with durvalumab or durvalumab plus tremelimumab in metastatic urothelial carcinoma

Marie Alt, Carlos Stecca, Yi‐An Lin, Gbenga Kazeem et autres

BACKGROUND: This retrospective analysis of data from clinical trials in metastatic urothelial carcinoma (mUC) was conducted to determine baseline patient characteristics associated with long-term survival (LTS) following treatment with immune checkpoint inhibitors. METHODS: Data for this analysis were from patients with platinum-refractory …

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Antrodia salmonea suppresses epithelial-mesenchymal transition/metastasis and Warburg effects by inhibiting Twist and HIF-1α expression in Twist-overexpressing head and neck squamous cell carcinoma cells

Jhih‐Hsuan Hseu, Yi‐An Lin, Sudhir Pandey, Chithravel Vadivalagan et autres

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[Application of mixture analysis methods in association between metals mixture exposure and DNA oxidative damage].

Y H Wang, H G Yuan, L Y Zhang, Yi‐An Lin et autres

Exposure to mixed metals causes elevated levels of DNA oxidative damage, and selenium, zinc, and nickel are significant exposure factors.

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Time Spent Interacting with Nature Is Associated with Greater Well-Being for Girl Scouts Before and during the COVID-19 Pandemic

Carly E. Gray, Peter H. Kahn, Joshua J. Lawler, Pooja Sarin Tandon et autres

The onset of the COVID-19 pandemic rendered daily life overwhelmingly difficult for many children. Given the compelling evidence for the physical and mental health benefits of interaction with nature, might it be the case that time spent interacting with nature buffered the …

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Climate Change: Anticipating and Adapting to the Impacts on Terrestrial Species

Joshua J. Lawler, Lauren E. Oakes, Ailene K. Ettinger, Yi‐An Lin

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Coenzyme Q0 defeats NLRP3-mediated inflammation, EMT/metastasis, and Warburg effects by inhibiting HIF-1α expression in human triple-negative breast cancer cells

Hsin‐Ling Yang, Ping‐Yu Lin, Chithravel Vadivalagan, Yi‐An Lin et autres

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Urinary excretion patterns and potential risks of beta‐blocker ophthalmic drops in sports

Yi‐An Lin, Wei‐Yu Chiang, Ming‐Tse Kuo, Alexander Chen et autres

Beta-blockers have been prohibited by the World Anti-Doping Agency (WADA) in certain sports, but insufficient research data make it difficult to distinguish between therapeutic uses or misuses. This study aimed at investigating the urinary excretion pattern following beta-blocker ophthalmic drops and the …

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