Accès ouvert
2025
article
OpenAlex
Qiang Huang, Yuxiang Sun, Peng‐Peng Kuang, Juan Sun et autres
Peritoneal dialysis (PD), as a renal replacement therapy, relies heavily on the structural and functional integrity of the peritoneum. In some patients, however, the peritoneum may undergo adverse remodeling and fibrotic thickening, resulting in treatment failure. Here, a previously unrecognized metabolic-epigenetic mechanism …
cn, pl, us
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Accès ouvert
2024
article
OpenAlex
Zhihao Huo, Dehui Liu, Peiyi Ye, Yuehang Zhang et autres
BACKGROUND: Relationship between serum phosphorus time in range and mortality risk in peritoneal dialysis (PD) patients remains uncertain. We aimed to evaluate the association between serum phosphorus time in range and all-cause mortality in Chinese PD population. METHODS: This was a multicenter, …
cn
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Accès ouvert
2024
article
OpenAlex
Xianhong Li, Xin Dong, Liangyou Zhang, Shu Zhang et autres
Background: In recent years, diabetic kidney disease (DKD) has emerged as a prominent factor contributing to end-stage renal disease. Tubulointerstitial inflammation and lipid accumulation have been identified as key factors in the development of DKD. Earlier research indicated that Astragaloside IV (AS-IV) …
cn
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Accès ouvert
2024
article
OpenAlex
Qingyao Zhu, Zhihao Huo, Fang Zeng, Nirong Gong et autres
BACKGROUND: Few reports have focused on the association between apparent treatment-resistant hypertension (aTRH) and cardiovascular (CV) mortality in peritoneal dialysis (PD) population, thus we conducted this retrospective cohort to explore it. METHODS: This was a retrospective cohort study conducted from January 2011 …
cn
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2024
article
OpenAlex
Xiwen Zhang, Zhihao Huo, Xiaotong Jia, Yuanyuan Xiong et autres
, a DN mouse model was generated by injecting STZ. The biochemical indicators of serum and urine, as well as renal histopathology and ultrastructure were analysed. To predict the mechanisms associated with (+)-catechin, network pharmacology and molecular docking were used. Finally, quantitative …
cn
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Accès ouvert
2022
article
OpenAlex
Zhihao Huo, Qianqian Zhuo, Shaoxin Zhong, Fang Wang et autres
Background: The association of hypokalemia (LK) with peritoneal dialysis-associated peritonitis (PDAP) risk remains uncertain. Here, we calculated LK duration in the first PD year and evaluated its association with PDAP. Methods: A multicenter, retrospective, incident cohort study of 1633 participants was conducted …
cn
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Accès ouvert
2022
article
OpenAlex
Dan Li, Zhihao Huo, Danyang Liu, Nirong Gong et autres
Apparent treatment-resistant hypertension (aTRH) is the most commonly used term to report resistant hypertension (RH) and is considered as a common problem in dialysis population. However, few reports have focused on peritoneal dialysis (PD) hypertensive patients. The authors conducted a multi-center cross-sectional …
cn
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Accès ouvert
2021
review
OpenAlex
Zhihao Huo, Huizhen Ye, Peiyi Ye, Guanqing Xiao et autres
BACKGROUND: IgA nephropathy (IgAN) is still one of the most prevalent forms of primary glomerulonephritis globally. However, no guidelines have clearly indicated which kinds of renin angiotensin system blockade therapies (ACEIs or ARBs or their combination) in patients with IgAN result in …
cn
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Accès ouvert
2020
article
OpenAlex
Huizhen Ye, Zhihao Huo, Peiyi Ye, Guanqing Xiao et autres
BACKGROUND: Both angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) are blood pressure-lowering agents, but they are also being used to control proteinuria in early chronic kidney disease (CKD) patients. However, clinically, some patients present merely proteinuria without hypertension. No guidelines …
cn
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2019
article
OpenAlex
Chao Xie, Shengjian Zhang, Jiali Tan, Jie Tian et autres
Objective To investigate the relationship between serum uric acid level and renal function decline by retrospective cohort study. Methods Through the physical examination system of the First People's Hospital of Foshan, the physical examination data from 2015 to 2018 of a public …
cn
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