Xiaoshan Geng

Metabolomics and transcriptomics reveal dynamic flavonoid metabolic responses in Isatis indigotica roots following leaf cutting

Huaxi Huang, Qiaoyun Cai, Xiaoshan Geng, Yan Qing et autres

The root of Isatis indigotica (Radix Isatidis) is a valuable traditional Chinese medicine rich in bioactive flavonoids, yet the regulatory mechanism by which leaf cutting affects root flavonoid metabolism remains unclear. In this two‑year (2024 and 2025) field experiment, we investigated the …

cn (code pays fourni par la source)

Comparative metabolomic and transcriptomic profiling of flavonoid diversity and antioxidant capacity in three Isatis species

Rong Chen, Yan Qing, Xiaoshan Geng, Qiaoyun Cai et autres

Flavonoids are key bioactive compounds in plants with significant health benefits. This study employs an integrated multi-omics approach to investigate flavonoid diversity and antioxidant capacity across three Isatis species: I. oblongata, I. tinctoria, and I. indigotica. Metabolomic profiling identified 200 flavonoids, with …

cn (code pays fourni par la source)

Stage-resolved multi-omics links flavonoid accumulation to antioxidant capacity in Isatis indigotica fruit

Rong Chen, Xiaoshan Geng, Lili Wang, Xuexue Wang et autres

Isatis indigotica fruit is an underutilized source of natural antioxidant ingredients. However, the developmental basis of its bioactive metabolites remains unclear. We integrated widely targeted metabolomics, transcriptomics, and antioxidant phenotyping across five fruit developmental stages (S1-S5) to characterize metabolic remodeling, identify flavonoid-related …

cn (code pays fourni par la source)

Deciphering lipid biosynthesis and regulation in Isatis species through combined metabolomic and transcriptomic analysis

Rong Chen, Qin Liu, Qiaoyun Cai, Yan Qing et autres

Lipids play multifaceted roles beyond structure and storage, yet their diversity within medicinally important genera like Isatis is poorly characterized. This study conducted the integrated lipidomic and transcriptomic analysis of three Isatis species, namely, I. oblongata, I. tinctoria, and I. indigotica. Lipidomics …

cn (code pays fourni par la source)

Integrative Metabolomic and Transcriptomic Profiling Reveals the Chemical and Molecular Basis for Aroma Divergence in Isatis Fruits

Rong Chen, Yan Qing, Xiaoshan Geng, Qiaoyun Cai et autres

ABSTRACT The fruits of Isatis species hold significant but underexplored potential in flavor and phytochemical applications. This study comprehensively investigated the volatile organic compounds (VOCs) and their transcriptional regulation underlying aroma divergence in the fruits of three Isatis species. Using headspace solid‐phase …

cn (code pays fourni par la source)

Metabolic profiling and pharmacological evaluation of alkaloids in three Murraya species

Xiaoshan Geng, Lili Wang, Xuexue Wang, Fanglin Liu et autres

This study comprehensively investigated the metabolic profiling, pharmacological potential, and biosynthetic regulation of alkaloids in three Murraya species (M. exotica, M. kwangsiensis, and M. tetramera). Through integrative multi-omics approaches, including metabolomics, transcriptomics, network pharmacology, and molecular docking, a total of 77 alkaloids …

cn (code pays fourni par la source)

FUT8-mediated core fucosylation stabilizes TMEM67 to promote ciliogenesis

Difei Wang, Qingchao Li, Junkui Zhao, Mingzheng Hu et autres

Glycosylation of membrane proteins plays an essential role in diverse biological processes. However, it remains unknown whether this posttranslational modification occurs on ciliary membrane proteins. Herein, by mass spectrometry-based proteomic analysis, we demonstrate that multiple membrane proteins localized in the ciliary transition …

cn (code pays fourni par la source)

Decoding the Chloroplast Genome of Bitterwood (Picrasma quassioides): Structure, Variability, and Evolutionary Relationships

Qin Liu, Jinhang Lin, Fanglin Liu, Xuexue Wang et autres

ABSTRACT The chloroplast genome of Picrasma quassioides, a medicinally significant plant in traditional Asian medicine, was sequenced and analyzed to understand its genetic architecture and evolutionary relationships within Simaroubaceae. High‐throughput sequencing revealed a 160,013‐bp circular genome with a typical quadripartite structure, encoding …

cn (code pays fourni par la source)

Genomic Resource Insights into Strain WZ-12: An Antimicrobial-Producing Streptomyces Isolate from Star Anise Rhizosphere Soil

Jieming Pan, Xiaoshan Geng, Yulin Zhu, Qin Liu

Strain WZ-12, isolated from the rhizosphere soil of star anise trees, exhibits significant antifungal efficacy against a variety of fungi, including Colletotrichum horii, the pathogenic fungus responsible for anthracnose in star anise. Based on 16S rRNA gene sequencing and phylogenetic analysis, the …

cn (code pays fourni par la source)

Codon usage bias analysis of the chloroplast genome of cassava

Xiaoshan Geng, Ning Huang, Yulin Zhu, Qin Liu et autres

Chloroplast codon preference affects gene expression efficiency and is important for chloroplast genetic engineering applications. Despite being the third most important food crop, cassava (Manihot esculenta) has received little attention for its chloroplast codon usage patterns. The analysis of cassava chloroplast genomic …

cn (code pays fourni par la source)

Characterization of the RACK1 gene of Aips cerana cerana and its role in adverse environmental stresses

Hongfei Wang, Yucai Xie, Xiaoqing Wang, Xiaoshan Geng et autres

cn (code pays fourni par la source)

The complete chloroplast genome sequence of Picrasma quassioides (D. Don) Benn. 1844 (Simaroubaceae)

Qin Liu, Xiaoshan Geng, Yi-Peng Guo, Huang Huaxi et autres

Picrasma quassioides is a member of the Simaroubaceae family and is widely used as a medicinal plant. In this study, we sequenced and assembled the complete chloroplast genome of P. quassioides. The chloroplast genome is 160,015 bp in length, with a large …

cn (code pays fourni par la source)