Mary Ellen Carey

Immune plasma for the treatment of severe influenza: an open-label, multicentre, phase 2 randomised study

Pablo Tebas, Marie-Carmelle Elie-Turenne, Ednan K. Bajwa, Todd E Bell et autres

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Intrapulmonary Disposition of Amphotericin B After Aerosolized Delivery of Amphotericin B Lipid Complex (Abelcet; ABLC) in Lung Transplant Recipients

Shahid Husain, Blair Capitano, Timothy E. Corcoran, Sean M. Studer et autres

BACKGROUND: Inhaled amphotericin preparations have been used for prophylaxis against invasive aspergillosis in lung transplant recipients. However, no published data exist regarding the pharmacokinetic profile of amphotericin B lipid complex in lung transplant recipients. METHODS: We prospectively determined the concentrations of amphotericin …

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Experience With Immune Monitoring in Lung Transplant Recipients: Correlation of Low Immune Function With Infection

Shahid Husain, K. Raza, Joseph M. Pilewski, Diana B. Zaldonis et autres

BACKGROUND: Lung transplants, in particular, have the highest rate of infections among solid organ transplant recipients. However, there is no existing objective measure to predict the development of infections. We report the correlation between Cylex ImmuKnow (ng/mL ATP) values and various infectious …

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Phase III multicenter web-based study demonstrating survival equivalents of nonplatinum-based chemotherapy for advanced non-small cell lung cancer (NSCLC): Subgroup analysis from D0112

James R. Rigas, Mary Ellen Carey, K. Dragnev, Sara A. Simeone et autres

8100 Background: Based on limited data, NSCLC guidelines from ASCO includes non-platinum (non-P) therapy. D0112 provided the highest evidence supporting this guideline. Survival for this non-P and a carboplatin combination were equivalent. Recently, treatment choices and duration are based on subgroups of …

223: Use of an Immune Monitoring Assay To Distinguish between Fungal Colonization and Fungal Disease in Lung Transplant Recipients

Sohail Z. Husain, Joseph M. Pilewski, Kathy J. Spichty, Diana B. Zaldonis et autres

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Safety assessment for the combination of docetaxel, carboplatin, and thoracic radiotherapy in unresectable stage III non-small cell lung cancer (NSCLC): A report of the first 100 patients treated with chemoradiation on D0410

James R. Rigas, Marcus Rubin, John M. Waples, K. Dragnev et autres

7701 Background: Concurrent chemoradiotherapy (chemoRT) is the preferred treatment for patients with unresectable stage III NSCLC. Limited safety information is available on the use of concurrent docetaxel, carboplatin and thoracic RT. We report the safety information on the initial 100 patients (pts) …

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451: Epidemiology of late bacterial pneumonia in a prospective cohort of lung transplant recipients (LTRs)

K. Raza, Sean M. Studer, David L. Paterson, Marta Crespo et autres

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Aerosol Deposition of Lipid Complex Amphotericin-B (Abelcet) in Lung Transplant Recipients

Timothy E. Corcoran, Ragothaman Venkataramanan, K.M. Mihelc, Amy L. Marcinkowski et autres

Lung transplant recipients exhibit a high incidence of invasive aspergillosis. The inhalation of lipid complex amphotericin-B (Abelcet; ABLC) offers a possible prophylactic strategy. The goals of this study were to select the optimal nebulizer delivery system for ABLC and to measure deposited …

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