Amir Hossein Ghanooni

Genetically Predicted 25‐Hydroxyvitamin D Levels on Hypothyroidism: A Two‐Sample Mendelian Randomization

Mahdi Akbarzadeh, Sahand Tehrani Fateh, Aysan Moeinafshar, Danial Habibi et autres

BACKGROUND: Alterations in levels of 25‐hydroxyvitamin D have been associated with the risk of thyroid disease. This study uses Mendelian randomization (MR) to infer the possible causal association of 25‐hydroxyvitamin D with hypothyroidism. METHODS: We performed two‐sample MR using the summary statistics …

Genetically Predicted 25‐Hydroxyvitamin D Levels on Hypothyroidism: A Two‐Sample Mendelian Randomization

Mahdi Akbarzadeh, Sahand Tehrani Fateh, Aysan Moeinafshar, Danial Habibi et autres

Abstract Background Alterations in levels of 25-Hydroxyvitamin D have been associated with the risk of thyroid disease. This study uses Mendelian randomization (MR) to infer the possible causal association of 25-Hydroxyvitamin D with hypothyroidism. Methods We performed two-sample MR using the summary …

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Cushing’s syndrome in a young woman due to prolonged betamethasone nasal drop use: a case report

Mohammadsadra Shamohammadi, Delaram Eskandari, Amir Ziaee, Seyed Hossein Samadanifard et autres

BACKGROUND: Cushing's syndrome is an uncommon but serious condition caused by long-term exposure to elevated cortisol levels, which is usually iatrogenic in origin. Although systemic corticosteroids are the most frequent agents, the association of intranasal corticosteroids with this condition is remarkably rare. …

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The Impact of Empagliflozin on Inflammatory Markers in Adults with Type 2 Diabetes: A Retrospective Cohort

Hossein Samadanifard, Zahra Barati, Amir Hossein Ghanooni, Delaram Eskandari et autres

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The Impact of Empagliflozin on Inflammatory Markers in Adults with Type 2 Diabetes: A Retrospective Cohort.

Hossein Samadanifard, Zahra Barati, Amir Hossein Ghanooni, Delaram Eskandari et autres

Background: Inflammation plays a significant role in the development and progression of type 2 diabetes (T2D). Empagliflozin, an SGLT2 inhibitor, has shown some anti-inflammatory effects in patients with T2D. This study aimed to evaluate the impact of empagliflozin on some inflammatory markers …

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Primary Hyperaldosteronism in a Normotensive Patient: A Case Report

Amir Hossein Ghanooni, Mitra KazemiJahromi, Farhad Hosseinpanah

Introduction: Primary aldosteronism (PA) is a clinical syndrome characterized by hypertension, suppressed plasma renin activity (PRA), elevated plasma aldosterone concentration (PAC), and spontaneous hypokalemia. Case Presentation: We present a 37-year-old normotensive female with hypokalemia, high plasma aldosterone level, and suppressed renin. The …

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The causal relationship between Graves’ disease and type 2 diabetes: Evidence from Bidirectional Mendelian Randomization Study

Mahdi Akbarzadeh, Mahsa Heidari‐Foroozan, Samaneh Talebi, Danial Habibi et autres

Abstract Introduction Numerous observational investigations have hinted at a possible link between Graves’ disease (GD) and the susceptibility to Type 2 diabetes (T2D). The primary objective of this study was to explore the potential underlying causal connection between GD and T2D through …

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Genetically predicted smoking behaviors on Graves’ disease: A two-sample mendelian randomization

Mahdi Akbarzadeh, Maryam Pourganji, Arefeh Tabashiri, Sahand Tehrani Fateh et autres

Abstract Background/Aim The potential link between smoking and the susceptibility to Graves’ disease (GD) has been scrutinized in observational studies, yielding inconsistent results. We conducted a Mendelian randomization (MR) analysis to ascertain the causal relationship between smoking behaviors and the risk of …

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Longitudinal Associations Between TPO Gene Variants and Thyroid Peroxidase Antibody Seroconversion in a Population-Based Study: Tehran Thyroid Study

Amir Hossein Ghanooni, Azita Zadeh–Vakili, Boshra Rezvankhah, Somayeh Jafari Nodushan et autres

Introduction:Autoimmune thyroid diseases (AITD) are usually accompanied by anti-thyroid antibodies which can serve as early predictive markers. This study was designed to investigate the relationship between thyroid peroxidase (TPO) gene variants and the presence of TPOAb and to evaluate the effect of …

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Longitudinal Associations Between TPO Gene Variants and TPOAb Seroconversion In A Population Based Study: Tehran Thyroid Study (TTS)

Amir Hossein Ghanooni, Azita Zadeh–Vakili, Boshra Rezvankhah, Somayeh Jafari Nodushan et autres

Abstract Background: Autoimmune thyroid diseases (AITD) are among the most common autoimmune diseases in the world. They are usually accompanied by the presence of anti-thyroid antibodies as the early predictive marker. Genetic determinants of the susceptibility to develop thyroid antibodies are still …

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Longitudinal Associations Between TPO Gene Variants and TPOAb Seroconversion in a Population Based Study: Tehran Thyroid Study (TTS)

Amir Hossein Ghanooni, Azita Zadeh–Vakili, Boshra Rezvankhah, Somayeh Jafari Nodushan et autres

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Frosted branch angiitis caused by Varicella Zoster virus in an immunocompetent patient.

Mahshid Talebi Taher, Ali Javadzadeh, Alireza Hedayatfar, Shahrzad Rahmani et autres

INTRODUCTION: Frosted branch angiitis(FBA) is a panuveitis with sheating of all retinal vesssels. CASE PRESENTATION: Herein we report an immunocompetent person who presented with fever, headache, atypical rash, and hazy vision. Ophthalmoscopy of both eyes revealed perivascular sheathing with frosted branch angiitis …

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