Maidah Yaqoob

Histological and clinical phenotypes of diabetic kidney disease: a baseline analysis of the HEROIC study

Gordon Paterson, Ortensia Vito, Lauren Heptinstall, M. Sheaff et autres

Background: Diabetic kidney disease (DKD) is increasingly recognized as a heterogeneous condition. Our understanding of the structure-function relationships underpinning DKD is limited. The East and North London Diabetes Cohort (HEROIC) study aims to identify prognostic markers in a diverse DKD cohort. We …

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Divergent roles of skeletal muscle 11β-HSD1 in age-related and chronic kidney disease-associated sarcopenia

Michael Sagmeister, Ana Crastin, Bradley Welsh, Louise Firkins et autres

BACKGROUND: Chronic kidney disease (CKD) is associated with increased incidence of sarcopenia and muscle weakness in aging patients. The glucocorticoid-activating enzyme11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) within skeletal muscle in these patients has been implicated in driving this process. We hypothesized that skeletal …

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Retraction Note: Delayed administration of pyroglutamate helix B surface peptide (pHBSP), a novel nonerythropoietic analog of erythropoietin, attenuates acute kidney injury

Nimesh S. A. Patel, Hannah L. Kerr-Peterson, Michael Brines, Massimo Collino et autres

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Clinical features, management, and outcomes of right heart thrombi: a retrospective cohort study

E. Fritzmann, Alexander Yuen, Stephanie Chang, Maidah Yaqoob et autres

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Evaluation and Management of Sepsis in Pulmonary Hypertension

Clare C. Prohaska, Maidah Yaqoob, Raju Reddy, M. Samant et autres

Pulmonary hypertension, characterized by elevated pressures in the pulmonary arteries leading to abnormalities in right ventricular function, may lead to competing demands between the pulmonary and systemic circulation during sepsis and septic shock. As a result, management of pulmonary hypertension in sepsis, …

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A qualitative exploration of cAregiver experienCes Of conseRvatively maNaged kidney failure: the ACORN study

Claire Carswell, Thomas Forbes, Anna Wilson, Gladys Laurente et autres

INTRODUCTION: Patients with kidney failure who are older, frail and have multiple conditions can choose not to receive dialysis and instead receive conservative management, which focuses on symptom management and maximising quality of life. Many of these patients rely on support from …

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Patients’ Lives Hung in a Pendulum of Negligence and Compromised Accountability

Zunaira Ashraf, Maidah Yaqoob

Background: Negligence and compromised accountability remain pressing issues in healthcare, often resulting in preventable patient harm and undermining trust in medical institutions. Despite established ethical codes and clinical guidelines, there is a notable gap in understanding how systemic factors and provider behavior …

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Comparative Analysis of the Health Care Systems of Pakistan and Nepal

Zunaira Ashraf, Maidah Yaqoob

Background: Health care systems are foundational to public well-being and vary significantly across nations, especially in low- and middle-income countries. Pakistan and Nepal, while geographically proximate, differ in system structures, resource allocation, and policy priorities. Objective: To compare and analyze the health …

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EARLY DETECTION OF RENAL CYST ON ULTRASONOGRAPHY AND THEIR ASSOCIATED RISK FACTORS

Rabia Jehangir, Maidah Yaqoob, Hira Tariq, Hafsa Quddos et autres

Background: Renal cysts are fluid-filled sacs that develop within or on the kidneys, often detected incidentally during routine ultrasonographic examinations. Although usually benign, renal cysts can be associated with systemic conditions and contribute to renal dysfunction in certain cases. Identifying their prevalence …

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Pulmonary Hypertension: Current State of the Art (Part II)

Yuri Matusov, Maidah Yaqoob, Michael I. Lewis

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Pulmonary Hypertension: Current State of the Art (Part I)

Yuri Matusov, Maidah Yaqoob, Michael I. Lewis

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Pulmonary Embolism Following Lung Transplantation: A Single-Center, Descriptive Review

Alexander Yuen, Maidah Yaqoob, Lorenzo Zaffiri

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