Zsolt Illés

Retinal vessel oxygen saturation is affected in multiple sclerosis and optic neuritis

Anna Bryndís Einarsdóttir, Sveinn Hákon Hardarson, Thomas Lee Torp, Zsolt Illés et autres

BACKGROUND: Structural and metabolic changes in the retina may serve as biomarkers in central nervous system disease. Optical coherence tomography studies have shown structural changes in the retina of patients with multiple sclerosis (MS). We aimed to find whether retinal oxygen levels …

is, dk (code pays fourni par la source)

Anti-CD20-tervezés és B-sejt-depletiós mechanizmusok sclerosis muliplexben

Zsolt Illés

The efficacy of anti-CD20 therapies in multiple sclerosis (MS) has been recognized since 2008. Since then, three anti-CD20 monoclonal antibodies - ocrelizumab, ofatumumab, and ublituximab - have been developed and approved for MS treatment, whereas rituximab, the first monoclonal antibody shown to …

dk, hu (code pays fourni par la source)

Anti-CD20-tervezés és B-sejt-depletiós mechanizmusok sclerosis muliplexben = Developing anti-CD20 molecules and B cell depletion in multiple sclerosis

Zsolt Illés

The efficacy of anti-CD20 therapies in multiple sclerosis (MS) has been recognized since 2008. Since then, three anti-CD20 monoclonal antibodies - ocrelizumab, ofatumumab, and ublituximab - have been developed and approved for MS treatment, whereas rituximab, the first monoclonal antibody shown to …

Phenotypic Changes in a Monocyte Cluster with High Interleukin‐1 Beta Expression during Long‐Term Anti‐ CD20 Therapy

Mie Waede, Christina Kingo, Karina Damsbo, Maiken Joergensen et autres

Objective We aimed to investigate disease‐related and anti‐CD20 therapy‐related changes in peripheral blood mononuclear cells (PBMCs) from multiple sclerosis (MS) patients compared to healthy controls (HC) using multi‐omics single‐cell analysis. Methods Targeted single‐cell sequencing of transcriptomes and epitopes was performed on PBMCs …

dk, de (code pays fourni par la source)

Bridging the 3D geometrical organisation of white matter pathways across anatomical length scales and species

Hans Martin Kjer, Mariam Andersson, Yi He, Alexandra Pacureanu et autres

We used diffusion MRI and x-ray synchrotron imaging on monkey and mice brains to examine the organisation of fibre pathways in white matter across anatomical scales. We compared the structure in the corpus callosum and crossing fibre regions and investigated the differences …

dk, cn, fr, it, de, ca (code pays fourni par la source)

Author response: Bridging the 3D geometrical organisation of white matter pathways across anatomical length scales and species

Hans Martin Kjer, Mariam Andersson, Yi He, Alexandra Pacureanu et autres

Common principles of white matter microstructure and pathway organisation was revealed using diffusion MRI and x-ray synchrotron imaging across resolutions, and employing diffusion tensor, micro-tensor, multi-fiber, and structure tensor models.

dk, fr, it, de, ca (code pays fourni par la source)

Bridging the 3D geometrical organisation of white matter pathways across anatomical length scales and species

Hans Martin Kjer, Mariam Andersson, Yi He, Alexandra Pacureanu et autres

We used diffusion MRI and x-ray synchrotron imaging on monkey and mice brains to examine the organisation of fibre pathways in white matter across anatomical scales. We compared the structure in the corpus callosum and crossing fibre regions and investigated the differences …

Author response: Bridging the 3D geometrical organisation of white matter pathways across anatomical length scales and species

Hans Martin Kjer, Mariam Andersson, Yi He, Alexandra Pacureanu et autres

We used diffusion MRI and x-ray synchrotron imaging on monkey and mice brains to examine the organisation of fibre pathways in white matter across anatomical scales. We compared the structure in the corpus callosum and crossing fibre regions and investigated the differences …

dk, fr, it, de, ca (code pays fourni par la source)

Bridging the 3D geometrical organisation of white matter pathways across anatomical length scales and species

Hans Martin Kjer, Mariam Andersson, Yi He, Alexandra Pacureanu et autres

Abstract We used diffusion MRI and x-ray synchrotron imaging on monkey and mice brains to examine the organisation of fibre pathways in white matter across anatomical scales. We compared the structure in the corpus callosum and crossing fibre regions and investigated the …

dk, cn, fr, it, de, ca (code pays fourni par la source)

Risk of hypertension in patients with multiple sclerosis treated with teriflunomide compared to dimethyl fumarate: A nationwide cohort study in Denmark

Elisabeth Framke, Finn Sellebjerg, Matthias Kant, Morten Stilund et autres

BACKGROUND: Teriflunomide has been associated with an increased risk of hypertension. Real-world studies including adequate control groups are lacking. We hypothesized that patients with multiple sclerosis (MS) treated with teriflunomide would be at higher risk of developing hypertension than those treated with …

dk (code pays fourni par la source)

Nationwide prevalence and incidence study of MOG-antibody associated disease in the adult population of Denmark

Viktoria Papp, Anna Christine Nilsson, Sepehr Mamoei, Jette Lautrup Frederiksen et autres

dk, ag, no (code pays fourni par la source)

Longitudinal analysis of peripheral immune cells in patients with multiple sclerosis treated with anti‐CD20 therapy

Mie Waede, Lasse Frank Voss, Christina Kingo, Jesper B. Moeller et autres

Abstract Objective Anti‐CD20 therapy is a highly effective treatment for multiple sclerosis (MS). In this study, we investigated MS‐related changes in peripheral blood mononuclear cell (PBMC) subsets compared to healthy controls and longitudinal changes related to the treatment. Methods Multicolor spectral flow …

dk, de (code pays fourni par la source)